Effects of the multidrug transporter P-glycoprotein on cellular responses to ionizing radiation.

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

1999 • 1,248 citations

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents.

1999 • 536 citations

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

1998 • 357 citations

Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.

1992 • 322 citations

P-Glycoprotein Protects Leukemia Cells Against Caspase-Dependent, but not Caspase-Independent, Cell Death

1999 • 308 citations

Up-regulation of Multidrug Resistance P-glycoprotein via Nuclear Factor-κB Activation Protects Kidney Proximal Tubule Cells from Cadmium- and Reactive Oxygen Species-induced Apoptosis

2000 • 305 citations

DNA damage and p53-mediated cell cycle arrest: A reevaluation

1996 • 216 citations

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

1996 • 206 citations

Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

1997 • 156 citations

bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells

1997 • 153 citations

BCL-2 expression delays drug-induced apoptosis but does not increase clonogenic survival after drug treatment in HeLa cells.

1995 • 144 citations

Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling.

1997 • 126 citations

Overexpression of P-glycoprotein in Mammalian Tumor Cell Lines After Fractionated X Irradiation In Vitro

1990 • 118 citations

P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake.

1996 • 108 citations

Applications of green fluorescent protein as a marker of retroviral vectors

1997 • 31 citations

Radiation resistance in a multidrug resistant human T-cell leukemia line

1988 • 19 citations

Multiple drug-resistant C6 glioma cells cross-resistant to irradiation.

1998 • 17 citations

Conferring drug resistance by MDR1 gene transfection increases susceptibility to irradiation and lipid peroxidation in 3T3 cell line

1996 • 11 citations

Collateral sensitivity to radiation and CIS-platinum in a multidrug-resistant human leukemia cell line

1995 • 9 citations