Phase I Trial of Intravenous Administration of PV701, an Oncolytic Virus, in Patients With Advanced Solid Cancers

A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

2000 • 1,092 citations

Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

2000 • 967 citations

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

2000 • 788 citations

Newcastle disease and other avian paramyxovirus

2000 • 658 citations

Clinical toxicity of interferons in cancer patients: a review.

1986 • 601 citations

A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer.

2000 • 426 citations

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action.

2000 • 370 citations

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

2001 • 278 citations

Newcastle disease virus selectively kills human tumor cells

1992 • 235 citations

Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer.

1987 • 216 citations

Newcastle disease virus as an antineoplastic agent

1965 • 214 citations

Tolerance to tumor necrosis factor in rats and the relationship to endotoxin tolerance and toxicity.

1988 • 199 citations

Circulating Interferon in Mice after Intravenous Injection of Virus

1963 • 164 citations

Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy.

1994 • 150 citations

Newcastle Disease Virus as an Antineoplastic Agent: Induction of Tumor Necrosis Factor- and Augmentation of Its Cytotoxicity2

1988 • 143 citations

Phase II study of recombinant leukocyte a interferon (rIFN-αA) in disseminated malignant melanoma

1984 • 140 citations

Complete Regression of Human Neuroblastoma Xenografts in Athymic Mice After Local Newcastle Disease Virus Therapy

1994 • 122 citations

A 15-Year Follow-up of AJCC Stage III Malignant Melanoma Patients Treated Postsurgically with Newcastle Disease Virus (NDV) Oncolysate and Determination of Alterations in the CD8 T Cell Repertoire

1998 • 109 citations

Immunization with virus-modified tumor cells.

1998 • 102 citations

A phase I clinical trial of recombinant human tumor necrosis factor given daily for five days

1989 • 82 citations

Newcastle disease virus activates macrophages for anti-tumor activity.

2000 • 67 citations

Newcastle disease virus infection induces B7-1/B7-2-independent T-cell costimulatory activity in human melanoma cells

2000 • 65 citations

Interleukin-6 release by rat liver macrophages

1990 • 58 citations

Scientific Interest in Newcastle Disease Virus Is Reviving

1999 • 58 citations

Molecular Biology: The Interferon System: A Review with Emphasis on the Role of PKR in Growth Control

1995 • 41 citations

Mouse genotype affects inducible expression of cytokine genes.

1992 • 39 citations

Analysis of the Interferons Induced in MiceIn Vivoand in MacrophagesIn Vitroby Newcastle Disease Virus and by Polyinosinic-Polycytidylic Acid

1986 • 30 citations

Phase II Trial of Recombinant Tumor Necrosis Factor in Disseminated Malignant Melanoma

1992 • 29 citations

CLINICAL STUDIES EMPLOYING INTERFERON INDUCERS IN MAN AND ANIMALS *

1970 • 23 citations

Reactions of Human Sera to Avian Adenoviruses and Newcastle Disease Virus

1971 • 18 citations

Newcastle disease virus antibodies in human sera.

1981 • 17 citations

Tumour lysis as a factor affecting blood levels of CEA

1982 • 9 citations

Preclinical studies with PV701, a replication-competent oncolytic strain of newcastle disease virus

2001 • 3 citations

Drug resistance

2001 • 1 citations

Systemic administration of replication-selective adenoviruses

2001 • 1 citations

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