Molecular architecture of a Leu3p-DNA complex in solution: a biochemical approach.

Current protocols in molecular biology

1988 • 4,543 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

DNA recognition by GAL4: structure of a protein-DNA complex

1992 • 664 citations

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

1980 • 524 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Purification and Properties of Drosophila Heat Shock Activator Protein

1987 • 388 citations

Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine

1982 • 208 citations

Determinants of Binding-Site Specificity Among Yeast C ₆ Zinc Cluster Proteins

1993 • 165 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

1988 • 162 citations

LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence.

1988 • 103 citations

In Vitro Transcriptional Activation by a Metabolic Intermediate: Activation by Leu3 Depends on α-Isopropylmalate

1992 • 98 citations

Role of an upstream regulatory element in leucine repression of the Saccharomyces cerevisiae leu2 gene

1984 • 75 citations

GAL4 Protein: Purification, Association with GAL80 Protein, and Conserved Domain Structure

1990 • 72 citations

Structure of yeast regulatory geneLEU3and evidence thatLEU3itself is under general amino acid control

1987 • 67 citations

[18] DNA contacts probed by modification protection and interference studies

1991 • 65 citations

Structure of the binuclear metal-binding site in the GAL4 transcription factor

1991 • 65 citations

Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger

1989 • 63 citations

Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2.

1990 • 47 citations

Yeast regulatory protein LEU3 : a structure-function analysis

1990 • 39 citations

GAL4 protein: purification, association with GAL80 protein, and conserved domain structure.

1990 • 34 citations

Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans.

1990 • 33 citations

Transcriptional regulator Leu3 of Saccharomyces cerevisiae: separation of activator and repressor functions.

1993 • 28 citations

Manipulation of the ‘Zinc cluster’ region of transcriptional activatorLEU3be site-directed mutagenesis

1991 • 26 citations

Purification and structural characterization of transcriptional regulator Leu3 of yeast.

1993 • 25 citations

Complete assignment of the ¹H NMR spectrum and secondary structure of the DNA binding domain of GAL4

1990 • 23 citations

The C6 Zinc Finger and Adjacent Amino Acids Determine DNA-Binding Specificity and Affinity in the Yeast Activator Proteins LAC9 and PPR1

1990 • 22 citations

The upstream activating sequence for L-leucine gene regulation inSaccharomyces cerevisiae

1990 • 22 citations

The C6 zinc finger and adjacent amino acids determine DNA-binding specificity and affinity in the yeast activator proteins LAC9 and PPR1.

1990 • 11 citations

The Leu3 protein: A metabolite-dependent transcriptional activator that is also a repressor

1993 • 3 citations

A molecular switch: Structure-function study of a yeast regulatory protein LEU3

1991 • 3 citations