In Vitro Transcriptional Activation by a Metabolic Intermediate: Activation by Leu3 Depends on α-Isopropylmalate

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein

1988 • 365 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence.

1988 • 103 citations

Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts.

1986 • 89 citations

Leucine biosynthesis in yeast

1983 • 83 citations

Role of an upstream regulatory element in leucine repression of the Saccharomyces cerevisiae leu2 gene

1984 • 75 citations

TheILVSgene ofSaccharomyces cerevisiaeis highly expressed

1986 • 72 citations

Structure of yeast regulatory geneLEU3and evidence thatLEU3itself is under general amino acid control

1987 • 67 citations

Structure of the binuclear metal-binding site in the GAL4 transcription factor

1991 • 65 citations

Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.

1991 • 59 citations

Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2.

1990 • 47 citations

A large internal deletion converts yeast LEU3 to a constitutive transcriptional activator.

1989 • 42 citations

CLONING AND CHARACTERIZATION OF YEAST LEU4, ONE OF TWO GENES RESPONSIBLE FOR α-ISOPROPYLMALATE SYNTHESIS

1984 • 40 citations

Yeast regulatory protein LEU3 : a structure-function analysis

1990 • 39 citations

Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans.

1990 • 33 citations

THE PRODUCT OF THE LEU-3 CISTRON AS A REGULATORY ELEMENT FOR THE PRODUCTION OF THE LEUCINE BIOSYNTHETIC ENZYMES OF NEUROSPORA

1973 • 28 citations

Manipulation of the ‘Zinc cluster’ region of transcriptional activatorLEU3be site-directed mutagenesis

1991 • 26 citations

[107] Isolation and chemical estimation of α-isopropylmalate and β-isopropylmalate

1970 • 21 citations

Expression of the yeast LEU4 gene is subject to four different modes of control

1990 • 18 citations