Regulated trafficking of neurotransmitter transporters: common notes but different melodies

Glutamate uptake

2001 • 3,867 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

GABA TRANSPORTER HETEROGENEITY: PHARMACOLOGY AND CELLULAR LOCALIZATION

1996 • 582 citations

Signaling Mechanisms That Regulate Glucose Transport

1999 • 525 citations

Gettin’ down with ubiquitin: turning off cell-surface receptors, transporters and channels

1999 • 461 citations

Molecular Basis of Insulin-stimulated GLUT4 Vesicle Trafficking

1999 • 417 citations

Amphetamine-induced loss of human dopamine transporter activity: An internalization-dependent and cocaine-sensitive mechanism

2000 • 410 citations

Phosphorylation and Sequestration of Serotonin Transporters Differentially Modulated by Psychostimulants

1999 • 387 citations

Membrane Trafficking Regulates the Activity of the Human Dopamine Transporter

1999 • 378 citations

Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

1997 • 377 citations

The Interaction of β-Arrestin with the AP-2 Adaptor Is Required for the Clustering of β2-Adrenergic Receptor into Clathrin-coated Pits

2000 • 374 citations

The Family of Na⁺/Cl⁻ Neurotransmitter Transporters

1998 • 360 citations

Regulated Trafficking of the Human Dopamine Transporter

1999 • 357 citations

Functional Interaction between Monoamine Plasma Membrane Transporters and the Synaptic PDZ Domain–Containing Protein PICK1

2001 • 344 citations

Phosphorylation and Regulation of Antidepressant-sensitive Serotonin Transporters

1998 • 312 citations

Glutamate Induces Rapid Upregulation of Astrocyte Glutamate Transport and Cell-Surface Expression of GLAST

1999 • 307 citations

Multiple Signaling Pathways Regulate Cell Surface Expression and Activity of the Excitatory Amino Acid Carrier 1 Subtype of Glu Transporter in C6 Glioma

1998 • 292 citations

Phosphorylation and modulation of brain glutamate transporters by protein kinase C.

1993 • 290 citations

Exposing Rats to a Predator Blocks Primed Burst Potentiation in the HippocampusIn Vitro

1999 • 275 citations

Biogenic amine transporters: regulation in flux

2000 • 245 citations

Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

2001 • 241 citations

Cocaine and Antidepressant-Sensitive Biogenic Amine Transporters Exist in Regulated Complexes with Protein Phosphatase 2A

2000 • 234 citations

Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18

2001 • 222 citations

The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms

2000 • 216 citations

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

1994 • 211 citations

The elusive transporters with a high affinity for glutamate

1993 • 195 citations

Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport V_max

1997 • 187 citations

Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins

1998 • 187 citations

Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes.

1997 • 186 citations

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 173 citations

Regulation of γ-Aminobutyric Acid (GABA) Transporters by Extracellular GABA

1999 • 164 citations

Expression Patterns and Regulation of Glutamate Transporters in the Developing and Adult Nervous System

1999 • 162 citations

Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A

2000 • 160 citations

The Dynamin-dependent, Arrestin-independent Internalization of 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptors Reveals Differential Sorting of Arrestins and 5-HT2A Receptors during Endocytosis

2001 • 158 citations

Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.

1998 • 157 citations

Inhibition of the High‐Affinity Brain Glutamate Transporter GLAST‐1 via Direct Phosphorylation

1997 • 155 citations

Second Messengers, Trafficking-Related Proteins, and Amino Acid Residues that Contribute to the Functional Regulation of the Rat Brain GABA Transporter GAT1

1997 • 140 citations

Rapid Stimulation of EAAC1‐Mediated Na⁺‐Dependent <scp>l</scp>‐Glutamate Transport Activity in C6 Glioma Cells by Phorbol Ester

1996 • 138 citations

Protein Kinase C Regulates the Interaction between a GABA Transporter and Syntaxin 1A

1998 • 136 citations

Platelet-derived Growth Factor Rapidly Increases Activity and Cell Surface Expression of the EAAC1 Subtype of Glutamate Transporter through Activation of Phosphatidylinositol 3-Kinase

2000 • 130 citations

Comparison of Na+-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1).

1996 • 119 citations

Glutamate transporter EAAC1 is expressed in neurons and glial cells in the rat nervous system

1999 • 109 citations

Serotonin 5-HT2A Receptors: Molecular Biology and Mechanisms of Regulation

1998 • 109 citations

Activation of High‐Affinity Uptake of Glutamate by Phorbol Esters in Primary Glial Cell Cultures

1991 • 108 citations

GLUT4 – At the Cross Roads Between Membrane Trafficking and Signal Transduction

2001 • 102 citations

Multiple G Protein-Coupled Receptors Initiate Protein Kinase C Redistribution of GABA Transporters in Hippocampal Neurons

1999 • 101 citations

Calcium- and Syntaxin 1-mediated Trafficking of the Neuronal Glycine Transporter GLYT2

2001 • 99 citations

Protein kinase C‐mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein

2001 • 96 citations

Functional Regulation of γ-Aminobutyric Acid Transporters by Direct Tyrosine Phosphorylation

2000 • 95 citations

Methamphetamine-induced rapid decrease in dopamine transporter function: role of dopamine and hyperthermia.

2000 • 92 citations

Substrate-induced up-regulation of Na+-dependent glutamate transport activity

2000 • 91 citations

Modulation of Serotonin Transporter Activity by a Protein Kinase C Activator and an Inhibitor of Type 1 and 2A Serine/Threonine Phosphatases

1997 • 90 citations

Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes

2001 • 88 citations

Rat C6 and human astrocytic tumor cells express a neuronal type of glutamate transporter

1996 • 79 citations

Pharmacology of the receptors for the phorbol ester tumor promoters

2000 • 71 citations

[21] Selective labeling of neurotransmitter transporters at the cell surface

1998 • 65 citations

Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes.

2001 • 64 citations

Sodium-dependent glutamate transport in Müller glial cells: regulation by phorbol esters

1999 • 62 citations

Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters

2001 • 57 citations

Expression of the GLT-1 subtype of Na+-dependent glutamate transporter: pharmacological characterization and lack of regulation by protein kinase C.

1999 • 54 citations

Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution

2001 • 52 citations

Roles of platelet-derived growth factor in the developing and mature nervous systems

1997 • 52 citations

Regulation of the Na+-dependent high affinity glutamate/aspartate transporter in cultured Bergmann glia by phorbol esters

1997 • 50 citations

Reversible activation of glutamate transport in rat brain glia by protein kinase C and an okadaic acid-sensitive phosphoprotein phosphatase.

1999 • 31 citations

Protein kinase‐mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 16 citations

The Ups and Downs of Neurotransmitter Transporters

2000 • 13 citations

Advances in molecular biology of neurotransmitter transporters

1992 • 12 citations