Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

1985 • 1,253 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments

1996 • 742 citations

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

1999 • 724 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat

1993 • 554 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study

1993 • 518 citations

Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat

1994 • 512 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

Regulated Trafficking of the Human Dopamine Transporter

1999 • 357 citations

Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors

1995 • 316 citations

Protein Kinase C-mediated Phosphorylation and Functional Regulation of Dopamine Transporters in Striatal Synaptosomes

1997 • 298 citations

Neurotransmitter transporters as molecular targets for addictive drugs

1998 • 294 citations

Dopamine release in the nucleus caudatus and in the nucleus accumbens is under glutamatergic control through non-NMDA receptors: a study in freely-moving rats

1990 • 260 citations

Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3

1995 • 238 citations

Dopamine D₂ Receptor‐Deficient Mice Exhibit Decreased Dopamine Transporter Function but No Changes in Dopamine Release in Dorsal Striatum

1999 • 233 citations

D₂ Receptors May Modulate the Function of the Striatal Transporter for Dopamine: Kinetic Evidence from Studies In Vitro and In Vivo

1993 • 232 citations

NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus

1990 • 221 citations

The glutamatergic nerve terminal

1993 • 221 citations

Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons

1998 • 215 citations

Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport V_max

1997 • 187 citations

Role of Protein Kinase C Phosphorylation in Rapid Desensitization of Metabotropic Glutamate Receptor 5

1998 • 187 citations

Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes.

1997 • 186 citations

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 173 citations

Regulation of the functional activity of the human dopamine transporter by protein kinase C

1997 • 161 citations

The Metabotropic Glutamate Receptor mGluR5 Induces Calcium Oscillations in Cultured Astrocytes via Protein Kinase C Phosphorylation

1997 • 138 citations

Phosphorylation and Calmodulin Binding of the Metabotropic Glutamate Receptor Subtype 5 (mGluR5) Are Antagonistic in Vitro

1997 • 134 citations

Phorbol esters alter functions of the expressed dopamine transporter

1994 • 118 citations

Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

1992 • 117 citations

Metabotropic Glutamate Receptor mGluR5 in Astrocytes: Pharmacological Properties and Agonist Regulation

1997 • 114 citations

Protein kinase C activators decrease dopamine uptake into striatal synaptosomes.

1996 • 99 citations

Regulation of striatal dopamine release by metabotropic glutamate receptors

1998 • 90 citations

The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons

1995 • 90 citations

Intrastriatal injection of a selective metabotropic excitatory amino acid receptor agonist induces contralateral turning in the rat.

1991 • 83 citations

Metabotropic glutamate receptors depress glutamate‐mediated synaptic input to rat midbrain dopamine neurones in vitro

1998 • 75 citations

Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons

1993 • 69 citations

Intrastriatal and intrasubthalamic stimulation of metabotropic glutamate receptors: A behavioral and Fos immunohistochemical study

1995 • 66 citations

Activation of Ca2+/calmodulin-dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes.

1994 • 62 citations

Persistent increase in dopamine release following activation of metabotropic glutamate receptors in the rat nucleus accumbens

1995 • 61 citations

Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1α metabotropic glutamate receptor

1998 • 54 citations

Group I mGlu receptor modulation of dopamine release in the rat striatum in vivo

1999 • 48 citations

Stimulation of Dopamine Release from Cultured Rat Mesencephalic Cells by Naturally Occurring Excitatory Amino Acids: Involvement of Both N‐Methyl‐D‐Aspartate (NMDA) and Non‐NMDA Receptor Subtypes

1990 • 39 citations

Correlation between (3H) dopamine specific uptake and (3H) GBR 12783 specific binding during the maturation of rat striatum

1989 • 34 citations

Increased dopamine uptake in striatal synaptosomes after treatment of rats with amantadine

2000 • 34 citations

Inhibitory effects of ascorbic acid on dopamine uptake by rat striatal synaptosomes: relationship to lipid peroxidation and oxidation of protein sulfhydryl groups

1998 • 33 citations

Cerebral Signal Transduction: From First to Fourth Messengers

2000 • 25 citations

Differential localization of the mRNAs for the pertussis toxin insensitive G-protein alpha sub-units Gq, G11, and Gz in the rat brain, and regulation of their expression after striatal deafferentation

1998 • 23 citations

Age-dependent differences in glutamate-induced phosphorylation systems in rat hippocampal slices

1999 • 22 citations

Protein kinase‐mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 16 citations

Possible Relationship between Changes in [3H]DA Uptake and Autoxidation in Rat Striatal Slices

1998 • 15 citations

Peroxidation of Synaptosomes Alters the Dopamine Uptake Complex but Spares the Exocytotic Release of Dopamine

1995 • 14 citations

Regulation of striatal dopamine release by metabotropic glutamate receptors

1998 • 8 citations

Regulation of Dopamine Transporter by Phosphorylation and Impact on Cocaine Action

2000 • 7 citations