A Human IAP-Family Gene, Apollon, Expressed in Human Brain Cancer Cells

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

Apoptosis. Its significance in cancer and cancer Therapy

1994 • 2,148 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1998 • 1,394 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1995 • 976 citations

Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

1989 • 937 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1997 • 648 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Apoptosis and the Dilemma of Cancer Chemotherapy

1997 • 615 citations

A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases

1998 • 611 citations

An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs

1994 • 530 citations

Control of Programmed Cell Death by the Baculovirus Genes p35 and iap

1994 • 517 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Induction of DNA strand breaks associated with apoptosis during treatment of leukemias.

1993 • 292 citations

A Giant Ubiquitin-conjugating Enzyme Related to IAP Apoptosis Inhibitors

1998 • 248 citations

The iap genes: unique arbitrators of cell death

1997 • 95 citations

Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.

1996 • 72 citations

Induction of apoptosis in murine tumors by cyclophosphamide

1994 • 61 citations