Amphetamine Blocks Long-Term Synaptic Depression in the Ventral Tegmental Area

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Predictive Reward Signal of Dopamine Neurons

1998 • 4,446 citations

Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions

1991 • 3,177 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

1992 • 1,675 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

1998 • 936 citations

Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization

1983 • 925 citations

The control of firing pattern in nigral dopamine neurons: single spike firing

1984 • 856 citations

Addictive Drugs and Brain Stimulation Reward

1996 • 777 citations

Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro

1989 • 734 citations

Dendritic release of dopamine in the substantia nigra

1981 • 732 citations

Two types of neurone in the rat ventral tegmental area and their synaptic inputs.

1992 • 682 citations

Release of dopamine from dendrites in rat substantia nigra

1976 • 644 citations

Long-Term Depression in Hippocampus

1996 • 583 citations

Neuroadaptations involved in amphetamine and cocaine addiction

1998 • 506 citations

Long-Term Synaptic Depression

1995 • 493 citations

Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801

1989 • 484 citations

Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents

1996 • 454 citations

Ca2+ Signaling Requirements for Long-Term Depression in the Hippocampus

1996 • 442 citations

Intrinsic primary afferent neuronsof the intestine

1998 • 399 citations

D1/D5 Dopamine Receptor Activation Increases the Magnitude of Early Long-Term Potentiation at CA1 Hippocampal Synapses

1996 • 374 citations

Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.

1993 • 368 citations

Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.

1988 • 328 citations

Properties and Plasticity of Excitatory Synapses on Dopaminergic and GABAergic Cells in the Ventral Tegmental Area

1999 • 317 citations

Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system.

1995 • 291 citations

Synaptic Regulation of Mesocorticolimbic Dopamine Neurons

1996 • 289 citations

Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons

1998 • 285 citations

Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

1995 • 263 citations

D₂Dopamine Receptors Reduce N-Type Ca²⁺Currents in Rat Neostriatal Cholinergic Interneurons Through a Membrane-Delimited, Protein-Kinase-C-Insensitive Pathway

1997 • 258 citations

A role for sensitization in craving and relapse in cocaine addiction

1998 • 251 citations

Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects

1990 • 251 citations

Modulation of Long-Term Depression by Dopamine in the Mesolimbic System

2000 • 211 citations

Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors.

1997 • 210 citations

Repeated Cocaine Administration Alters Extracellular Glutamate in the Ventral Tegmental Area

1998 • 186 citations

Dopamine Selectively Inhibits the Direct Cortical Pathway to the CA1 Hippocampal Region

1999 • 181 citations

Development of both conditioning and sensitization of the behavioral activating effects of amphetamine is blocked by the non-competitive NMDA receptor antagonist, MK-801

1993 • 180 citations

Acute and Repeated Systemic Amphetamine Administration: Effects on Extracellular Glutamate, Aspartate, and Serine Levels in Rat Ventral Tegmental Area and Nucleus Accumbens

1996 • 178 citations

D1/D5 Dopamine Receptors Inhibit Depotentiation at CA1 Synapses via cAMP-Dependent Mechanism

1998 • 167 citations

Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors

1995 • 145 citations

Neural substrates of drug craving and relapse in drug addiction

1998 • 132 citations

A whole cell patch-clamp study on the pacemaker potential in dopaminergic neurons of rat substantia nigra compacta

1993 • 124 citations

Perturbed dentate gyrus function in serotonin 5-HT _2C receptor mutant mice

1998 • 116 citations

Amphetamine Depresses Excitatory Synaptic Transmission via Serotonin Receptors in the Ventral Tegmental Area

1999 • 102 citations

Long-term potentiation at excitatory amino acid synapses on midbrain dopamine neurons

1999 • 102 citations

Dopamine actions on calcium currents, potassium currents and hormone release in rat melanotrophs.

1991 • 87 citations

Sensitization to cocaine's motor activating properties produced by electrical kindling of the medial prefrontal cortex but not of the hippocampus

1994 • 70 citations

Amphetamine‐Induced Glutamate Efflux in the Rat Ventral Tegmental Area Is Prevented by MK‐801, SCH 23390, and Ibotenic Acid Lesions of the Prefrontal Cortex

1999 • 67 citations

Evidence for drug actions on both pre- and postsynaptic catecholamine receptors in the CNS.

1975 • 64 citations

In Vivo and in Vitro Intracellular Recordings from Rat Midbrain Dopamine Neuronsa

1988 • 64 citations

Activation of Human D3 Dopamine Receptor Inhibits P/Q-Type Calcium Channels and Secretory Activity in AtT-20 Cells

1999 • 59 citations

Chronic administration of (+)-amphetamine alters the reactivity of midbrain dopaminergic neurons to prefrontal cortex stimulation in the rat

1995 • 57 citations

Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat

1998 • 55 citations

Pharmacology of high‐threshold calcium currents in GH₄C₁ pituitary cells and their regulation by activation of human D₂ and D₄ dopamine receptors

1994 • 50 citations

AMPA antagonist LY293558 blocks the development, without blocking the expression, of behavioral sensitization to morphine

1999 • 41 citations

Can the ”state-dependency" hypothesis explain prevention of amphetamine sensitization in rats by NMDA receptor antagonists?

1999 • 38 citations

Acute amphetamine-induced subsensitivity of A10 dopamine autoreceptors in vitro

1991 • 37 citations

Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro

1996 • 35 citations

Dopamine D₂‐Receptor Isoforms Expressed in AtT20 Cells InhibitQ‐Type High‐Voltage‐Activated Ca²⁺ Channels via a Membrane‐Delimited Pathway

1999 • 11 citations

Modulation of Ca Channels in Peripheral Neurons^a

1989 • 8 citations

Evidence for drug actions on both pre- and postsynaptic catecholamine receptors in the CNS.

1975 • 6 citations