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Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

Data up to Jan 2025

Published1995
Citations263
References163

Total Citations Per Year

Abstract

References (163)

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Handbook of Chemical Neuroanatomy

1986 • 4,276 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis

1986 • 2,110 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis

1986 • 1,751 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

1989 • 1,570 citations

An autoradiographic study of the organization of the efferet connections of the hippocampal formation in the rat

1977 • 1,546 citations

The amygdalostriatal projection in the rat—an anatomical study by anterograde and retrograde tracing methods

1982 • 884 citations

Tyrosine hydroxylase-immunoreactive boutons in synaptic contact with identified striatonigral neurons, with particular reference to dendritic spines

1984 • 866 citations

Limbic lesions and the problem of stimulus—Reinforcement associations

1972 • 865 citations

Organization of the projections from the subiculum to the ventral striatum in the rat. A study using anterograde transport of Phaseolus vulgaris leucoagglutinin

1987 • 857 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris‐leucoagglutinin

1991 • 827 citations

An autoradiographic examination of corticocortical and subcortical projections of the mediodorsal‐projection (prefrontal) cortex in the rat

1979 • 787 citations

Neurotransmission in the rat amygdala related to fear and anxiety

1994 • 781 citations

The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde and retrograde-horseradish peroxidase study

1982 • 741 citations

Stimulants : neurochemical, behavioral, and clinical perspectives

1983 • 689 citations

Involvement of the amygdala in stimulus-reward associations: Interaction with the ventral striatum

1989 • 662 citations

The Mesolimbic Dopamine System: From Motivation to Action

1992 • 591 citations

The mesolimbic dopamine system : from motivation to action

1991 • 555 citations

Afferent projections to the ventral tegmental area of Tsai and interfascicular nucleus: A horseradish peroxidase study in the rat

1979 • 550 citations

The basolateral amygdala-ventral striatal system and conditioned place preference: Further evidence of limbic-striatal interactions underlying reward-related processes

1991 • 507 citations

Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals

1993 • 502 citations

Catecholamine innervation of the basal forebrain II. Amygdala, suprarhinal cortex and entorhinal cortex

1978 • 487 citations

Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801

1989 • 484 citations

Chemical and structural analysis of the relation between cortical inputs and tyrosine hydroxylase-containing terminals in rat neostriatum

1984 • 467 citations

Organization of amygdaloid projections to the prefrontal cortex and associated striatum in the rat

1991 • 456 citations

Persistent sensitization of dopamine neurotransmission in ventral striatum (nucleus accumbens) produced by prior experience with (+)-amphetamine: a microdialysis study in freely moving rats

1988 • 455 citations

In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spiny neurons and are in apposition to each other

1990 • 443 citations

Burst Firing in Dopamine Neurons Induced by N -Methyl-D-aspartate: Role of Electrogenic Sodium Pump

1992 • 433 citations

Extrinsic projections from area CA1 of the rat hippocampus: Olfactory, cortical, subcortical, and bilateral hippocampal formation projections

1990 • 408 citations

A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis

1987 • 404 citations

Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya

1993 • 398 citations

Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.

1993 • 368 citations

Sensitization in the Nervous System

2024 • 359 citations

Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens.

1991 • 359 citations

Amygdaloid projections to the frontal cortex and the striatum in the rat

1990 • 348 citations

Excitatory amino acid projections to the nucleus accumbens septi in the rat: A retrograde transport study utilizingd[3H]aspartate and [3H]GABA

1987 • 339 citations

The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat

1974 • 330 citations

Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.

1988 • 328 citations

Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area

1992 • 315 citations

Neuronal architecture in the rat central nucleus of the amygdala: A cytological, hodological, and immunocytochemical study

1986 • 298 citations

Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions ofd-amphetamine

1993 • 296 citations

Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine

1995 • 293 citations

Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system.

1995 • 291 citations

Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices

1988 • 281 citations

Connections of the subthalamic nucleus with ventral striatopallidal parts of the basal ganglia in the rat

1990 • 277 citations

Current Developments in Psychopharmacology

1981 • 275 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration.

1989 • 273 citations

Morphological evidence for a dopaminergic terminal field in the hippocampal formation of young and adult rat

1985 • 273 citations

Convergence of hippocampal and dopaminergic input onto identified neurons in the nucleus accumbens of the rat.

1989 • 270 citations

Differential development of autoreceptor subsensitivity and enhanced dopamine release during amphetamine sensitization.

1993 • 255 citations

Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects

1990 • 251 citations

Intracellular study of rat substantia nigra pars reticulata neurons in an in vitro slice preparation: electrical membrane properties and response characteristics to subthalamic stimulation

1987 • 243 citations

Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization

1993 • 242 citations

Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine

1991 • 238 citations

Electrophysiological responses of neurones in the nucleus accumbens to hippocampal stimulation and the attenuation of the excitatory responses by the mesolimbic dopaminergic system

1984 • 235 citations

Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area

1985 • 231 citations

Role of the subthalamic nucleus in the regulation of nigral dopamine neuron activity

1992 • 231 citations

Inhibitory influence of the mesocortical dopaminergic system on spontaneous activity or excitatory response induced from the thalamic mediodorsal nucleus in the rat medial prefrontal cortex

1984 • 228 citations

Stereotyped behaviour patterns and hyperactivity induced by amphetamine and apomorphine after discrete 6-hydroxydopamine lesions of extrapyramidal and mesolimbic nuclei

1977 • 225 citations

The lateral nucleus of the amygdala mediates expression of the amphetamine-produced conditioned place preference

1991 • 221 citations

Organization of amygdaloid projections to brainstem dopaminergic, noradrenergic, and adrenergic cell groups in the rat

1992 • 217 citations

Response of nucleus accumbens neurons to amygdala stimulation and its modification by dopamine

1982 • 211 citations

Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat

1992 • 206 citations

Anatomy and Physiology of the Subthalamic Nucleus: A Driving Force of the Basal Ganglia

1987 • 206 citations

MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine

1994 • 203 citations

Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study.

1989 • 201 citations

Alterations of the GluR-B AMPA receptor subunit flip/flop expression in kainate-induced epilepsy and ischemia

1993 • 196 citations

The psychoses of epilepsy

1991 • 193 citations

Cocaine : pharmacology, physiology, and clinical strategies

1992 • 193 citations

In vivo microdialysis reveals a diminished amphetamine-induced DA response corresponding to behavioral sensitization produced by repeated amphetamine pretreatment

1992 • 192 citations

Electrophysiological evidence for A10 dopamine autoreceptor subsensitivity following chronicd-amphetamine treatment

1984 • 189 citations

Amphetamine behavioral sensitization and the excitatory amino acids

1990 • 188 citations

Biochemical evidence for overlapping neocortical and allocortical glutamate projections to the nucleus accumbens and rostral caudatoputamen in the rat brain

1981 • 180 citations

Excitatory Amino Acid Pathway from the Hippocampus to the Prefrontal Cortex. Contribution of AMPA Receptors in Hippocampo‐prefrontal Cortex Transmission

1992 • 180 citations

Development of both conditioning and sensitization of the behavioral activating effects of amphetamine is blocked by the non-competitive NMDA receptor antagonist, MK-801

1993 • 180 citations

Handbook of chemical neuroanatomy, Vol. 2: Classical Transmitters in the CNS

1986 • 179 citations

Amygdalonigral pathway: An anterograde study in the rat with Phaseolus vulgaris leucoagglutinin (PHA‐L)

1990 • 174 citations

Hippocampal signal transmission to the pedunculopontine nucleus and its regulation by dopamine D2 receptors in the nucleus accumbens: An electrophysiological and behavioural study

1987 • 166 citations

Amphetamine injected into the ventral tegmental area sensitizes the nucleus accumbens dopaminergic response to systemic amphetamine: an in vivo microdialysis study in the rat

1993 • 165 citations

Input from the amygdala to the rat nucleus accumbens: Its relationship with tyrosine hydroxylase immunoreactivity and identified neurons

1994 • 164 citations

DNQX blockade of amphetamine behavioral sensitization

1991 • 163 citations

The neurobiology of Drug and alcohol addiction

1991 • 154 citations

Selective up-regulation of an nmda receptor subunit mrna in cultured cerebellar granule cells by K+-induced depolarization and nmda treatment

1994 • 153 citations

An Excitant Amino Acid Projection from the Medial Prefrontal Cortex to the Anterior Part of Nucleus Accumbens in the Rat

1985 • 151 citations

Local cooling of pre‐frontal cortex induces pacemaker‐like firing of dopamine neurons in rat ventral tegmental area in vivo

1989 • 151 citations

The effects of surgical and chemical lesions on neurotransmitter candidates in the nucleus accumbens of the rat

1979 • 149 citations

Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices

1991 • 145 citations

Prevention of denervation atrophy in muscle: Mammalian neurotrophic factor is not transferrin

1984 • 144 citations

Hippocampal inputs to identified neurons in an in vitro slice preparation of the rat nucleus accumbens: evidence for feed-forward inhibition

1991 • 139 citations

Differential effects of excitotoxic lesions of the amygdala on cocaine-induced conditioned locomotion and conditioned place preference

1993 • 136 citations

MK‐801 prevents the development of behavioral sensitization during repeated morphine administration

1994 • 135 citations

The Basal Ganglia Ii: Structure And Function-Current Concepts

2012 • 133 citations

The cortico-nigral projection: reduced glutamate content in the substantia nigra following frontal cortex ablation in the rat

1984 • 133 citations

Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat

1990 • 128 citations

Behavioral Characterization of d - and l -Amphetamine: Neurochemical Implications

1975 • 124 citations

Topographic organization of collateral projections from the basolateral amygdaloid nucleus to both the prefrontal cortex and nucleus accumbens in the rat

1994 • 123 citations

The mesocorticolimbic dopamine system.

1988 • 123 citations

A10 somatodendritic dopamine autoreceptor sensitivity following withdrawal from repeated cocaine treatment

1990 • 122 citations

Efferent connections of the subthalamic region in the rat. I. The subthalamic nucleus of luys

1980 • 120 citations

6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: Effect on amphetamine-induced stereotyped behavior in rats

1974 • 116 citations

Cocaine behavioral sensitization and the excitatory amino acids

1994 • 115 citations

NMDA receptors mediate the behavioral effects of amphetamine infused into the nucleus accumbens

1992 • 114 citations

Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus

1993 • 113 citations

Contribution of the amygdala to learning and performance of conditional fear

1992 • 110 citations

Neuroleptic-like distruption of the conditioned avoidance response requires destruction of both the mesolimbic and nigrostriatal dopamine systems

1984 • 110 citations

Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: The role of behavioural competition

1984 • 108 citations

Evidence for the presence of N-methyl-d-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study

1990 • 103 citations

Competitive and noncompetitive NMDA antagonists block sensitization to methamphetamine

1994 • 102 citations

In vivo stereological assessment of caudate volume in man: Effect of normal aging

1990 • 102 citations

Contribution of NMDA receptors to postsynaptic potentials and paired-pulse facilitation in identified neurons of the rat nucleus accumbens in vitro

1991 • 99 citations

Inhibitory influence of the mesocortical dopaminergic neurons on their target cells: electrophysiological and pharmacological characterization.

1991 • 96 citations

Baclofen and adenosine inhibit synaptic potentials mediated by gamma-aminobutyric acid and glutamate release in rat nucleus accumbens.

1991 • 91 citations

Cocaine-Induced Behavioral Sensitization and Kindling: Implications for the Emergence of Psychopathology and Seizures

1988 • 88 citations

Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats

1989 • 87 citations

Electrophysiological evidence for the existence of NMDA and non‐NMDA receptors on rat ventral tegmental dopamine neurons

1993 • 87 citations

Two dissociable components of behavioral sensitization following repeated amphetamine administration

1982 • 87 citations

Differential regulation of N-methyl-d-aspartate receptor subunit messenger RNAs in kindling-induced epileptogenesis

1993 • 86 citations

Non-DA prefronto-cortical efferents modulate D1 receptors in the nucleus accumbens

1984 • 84 citations

Glutamate in cortical fibers.

1981 • 83 citations

Sensitization to systemic amphetamine produces an enhanced locomotor response to a subsequent intra-accumbens amphetamine challenge in rats

1991 • 80 citations

Conditioned Sensitization to the Psychomotor Stimulant Cocaine

1992 • 75 citations

The Neurobiology of Cocaine: Cellular and Molecular Mechanisms

1995 • 75 citations

Hippocampal control of behavioral arousal: Duration of lesion effects and possible interactions with recovery after frontal cortical damage

1971 • 74 citations

Hippocampal modulation of nucleus accumbens: Behavioral evidence from amphetamine-induced activity profiles

1991 • 74 citations

Apomorphine and amphetamine stereotypy after 6-hydroxydopamine lesions of the substantia nigra

1974 • 73 citations

Chronic d-amphetamine in nucleus accumbens: Lack of tolerance or reverse tolerance of locomotor activity

1981 • 72 citations

Characterization of fimbria input to nucleus accumbens

1985 • 71 citations

Sensitization to cocaine's motor activating properties produced by electrical kindling of the medial prefrontal cortex but not of the hippocampus

1994 • 70 citations

Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA

1990 • 69 citations

Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons

1993 • 69 citations

Potentiation of behavioral arousal after cortical damage and subsequent recovery

1969 • 68 citations

Enhanced amphetamine responses after frontal cortex lesions in the rat

1971 • 68 citations

Long-term amphetamine treatment attenuates or reverses the depression of neuronal activity produced by dopamine agonists in the ventral tegmental area

1984 • 66 citations

Electrophysiological responses of neurons of the ventral tegmental area to electrical stimulation of amygdala and lateral septum

1981 • 62 citations

AMPA/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists

1993 • 59 citations

Effect of pretreatment with amphetamine on the interaction between amphetamine and dopamine neurons in the nucleus accumbens

1989 • 58 citations

Membrane properties and synaptic responses of the guinea pig nucleus accumbens neurons in vitro

1989 • 58 citations

l-Glutamate excitation of A10 dopamine neurons is preferentially mediated by activation of NMDA receptors: extra- and intracellular electrophysiological studies in brain slices

1993 • 58 citations

Behavioral and neurochemical characteristics of stimulant-induced augmentation.

1987 • 49 citations

MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens

1994 • 49 citations

Changes in amphetamine sensitivity following frontal cortical damage in rats and mice

1972 • 48 citations

Changes in sensitivity to amphetamine in rats with chronic brain lesions.

1961 • 45 citations

alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonists in the nucleus accumbens and ventral pallidum decrease the hypermotility response to psychostimulant drugs.

1992 • 45 citations

Epilepsy, psychosis and schizophrenia

1988 • 44 citations

Blockade of behavioral sensitization to methamphetamine by lesion of hippocampo-accumbal pathway

1991 • 40 citations

Excitatory amino acid receptors mediate the orofacial stereotypy elicited by dopaminergic stimulation of the ventrolateral striatum

1994 • 40 citations

A voltage-clamp analysis of NMDA-induced responses on dopaminergic neurons of the rat subtantia nigra zona compacta and ventral tegmental area

1992 • 37 citations

Neurochemical Studies of the Mesolimbic Dopaminergic Pathway: Glycinergic Mechanisms and Glycinergic‐Dopaminergic Interactions in the Rat Ventral Tegmentum

1982 • 28 citations

Removal of optic tectum prolongs the cell body reaction to axotomy in goldfish retinal ganglion cells

1985 • 28 citations

Repeated stimulation of the ventral tegmental area sensitizes the hyperlocomotor response to amphetamine

1994 • 28 citations

AMPA/kainic acid glutamate receptor antagonism in the zona incerta dorsal to the subthalamic nucleus inhibits amphetamine-induced stereotypy but not locomotor activity

1992 • 27 citations

Hyperactivity following intradentate injection of colchicine: A role for dopamine systems in the nucleus accumbens

1990 • 26 citations

Involvement of the fimbria fornix in the initiation but not in the expression of methamphetamine-induced sensitization

1993 • 24 citations

The effects of cortical ablation on d-amphetamine-induced changes in striatal dopamine turnover and ascorbic acid catabolism in the rat

1992 • 19 citations

The effects of amygdaloid stimulation on amphetamine-elicited locomotor sensitization

1993 • 17 citations

Chapter 8 Contributions of the amygdalar complex to behavior in macaque monkeys

1991 • 16 citations

Synaptic potentials mediated by excitatory amino acid receptors in the nucleus accumbens of the rat, in vitro

1990 • 13 citations

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Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization… (1995) – Neuroscience | Metascience Observatory Explorer