Relations between the intracellular pathways of the receptors for transferrin, asialoglycoprotein, and mannose 6-phosphate in human hepatoma cells.

A new method of preparing gold probes for multiple-labeling cytochemistry.

1985 • 1,417 citations

The Role of Surface Carbohydrates in the Hepatic Recognition and Transport of Circulating Glycoproteins

1974 • 1,200 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

LYSOSOMAL ENZYMES AND THEIR RECEPTORS

1986 • 915 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

THE ENZYMATIC IODINATION OF THE RED CELL MEMBRANE

1972 • 709 citations

Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.

1983 • 603 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Trafficking of lysosomal enzymes in normal and disease states.

1986 • 445 citations

Use of colloidal gold particles in double-labeling immunoelectron microscopy of ultrathin frozen tissue sections.

1981 • 387 citations

The Phosphomannosyl Recognition System for Intracellular and Intercellular Transport of Lysosomal Enzymes

1982 • 379 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

Primary structure of human transferrin receptor deduced from the mRNA sequence

1984 • 351 citations

The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence

1984 • 337 citations

Possible pathways for lysosomal enzyme delivery.

1985 • 253 citations

Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles.

1988 • 241 citations

Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells.

1984 • 202 citations

Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver.

1985 • 193 citations

Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor.

1988 • 190 citations

The Hepatic Asialoglycoprotein Recepto

1984 • 185 citations

Sequence of human asialoglycoprotein receptor cDNA. An internal signal sequence for membrane insertion.

1985 • 182 citations

Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes.

1982 • 178 citations

Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes.

1987 • 174 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

Intracellular segregation of asialoglycoproteins and their receptor: a prelysosomal event subsequent to dissociation of the ligand-receptor complex.

1984 • 168 citations

The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors

1983 • 161 citations

Membranes of sorting organelles display lateral heterogeneity in receptor distribution.

1987 • 158 citations

Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells.

1987 • 147 citations

Sorting and recycling of cell surface receptors and endocytosed ligands: The asialoglycoprotein and transferrin receptors

1983 • 142 citations

The pathways of endocytosed transferrin and secretory protein are connected in the trans-Golgi reticulum.

1988 • 132 citations

Shift of equilibrium density induced by 3,3'-diaminobenzidine cytochemistry: a new procedure for the analysis and purification of peroxidase-containing organelles.

1984 • 132 citations

Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?

1987 • 123 citations

Receptor-mediated endocytosis of asialoglycoproteins by rat hepatocytes: receptor-positive and receptor-negative endosomes.

1986 • 121 citations

Biosynthesis of the human asialoglycoprotein receptor.

1983 • 119 citations

Biosynthesis, intracellular transport, and release of the Golgi enzyme galactosyltransferase (lactose synthetase A protein) in HeLa cells.

1982 • 115 citations

Vesicular stomatitis virus glycoprotein, albumin, and transferrin are transported to the cell surface via the same Golgi vesicles.

1983 • 107 citations

Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts.

1984 • 104 citations

Cell Biology of the Asialoglycoprotein Receptor System: A Model of Receptor-Mediated Endocytosis

1985 • 100 citations

Two asialoglycoprotein receptor polypeptides in human hepatoma cells.

1987 • 95 citations

Intracellular pools of transferrin receptors result from constitutive internalization of unoccupied receptors.

1986 • 94 citations

Effect of lysosomotropic amines on the secretory pathway and on the recycling of the asialoglycoprotein receptor in human hepatoma cells.

1985 • 94 citations

9 Localization of Macromolecular Components by Application of the Immunogold Technique on Cryosectioned Bacteria

1988 • 88 citations

The pathway of the asialoglycoprotein-ligand during receptor-mediated endocytosis: a morphological study with colloidal gold/ligand in the human hepatoma cell line, Hep G2.

1983 • 78 citations

Characterization of endocytic compartments using the horseradish peroxidase-diaminobenzidine density shift technique.

1987 • 76 citations

Partial resialylation of human asialotransferrin type 3 in the rat.

1982 • 72 citations

Asialoglycoprotein receptor phosphorylation and receptor-mediated endocytosis in hepatoma cells. Effect of phorbol esters.

1988 • 69 citations

46-kDa Mannose 6-phosphate-Specific Receptor: Purification, Subunit Composition, Chemical Modification

1987 • 68 citations

Ultrastructural immunocytochemical localization of the phosphomannosyl receptor in Chinese hamster ovary (CHO) cells.

1983 • 61 citations

Recycling of the hepatic asialoglycoprotein receptor in isolated rat hepatocytes. Receptor-ligand complexes in an intracellular slowly dissociating pool return to the cell surface prior to dissociation.

1984 • 61 citations

The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis.

1987 • 59 citations

Disproportional immunostaining patterns of two secretory proteins in guinea pig and rat exocrine pancreatic cells. An immunoferritin and fluorescence study.

1980 • 57 citations

A cycloheximide-resistant pool of receptors for asialoglycoproteins and mannose 6-phosphate residues in the Golgi complex of hepatocytes.

1984 • 57 citations

Ligand- and weak base-induced redistribution of asialoglycoprotein receptors in hepatoma cells.

1987 • 51 citations

Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol

1985 • 49 citations

Cellular pathways of galactose-terminal ligand movement in a cloned human hepatoma cell line.

1984 • 40 citations

Kinetics of internalization and degradation of asialo-glycoproteins in isolated rat hepatocytes.

1980 • 28 citations

In situ 125I-labelling of endosome proteins with lactoperoxidase conjugates.

1984 • 21 citations

Diacytosis of human asialotransferrin type 3 in the rat liver is due to the sequential engagement of two receptors

1985 • 16 citations

Presence of asialoglycoprotein receptors in the Golgi complex in the absence of protein synthesis

1986 • 12 citations