Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy

1993 • 5,296 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension.

1986 • 1,210 citations

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

1995 • 1,118 citations

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass.

1985 • 931 citations

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

1992 • 680 citations

Renal injury from angiotensin II-mediated hypertension.

1992 • 546 citations

Interactions of Transforming Growth Factor-β and Angiotensin II in Renal Fibrosis

1998 • 441 citations

Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats

1998 • 402 citations

Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction

1995 • 332 citations

Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat.

1998 • 328 citations

Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation

1993 • 295 citations

Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney

1994 • 214 citations

Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats

1994 • 208 citations

Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition

1997 • 199 citations

Macrophages, monocyte chemoattractant peptide-1, and TGF-beta 1 in experimental hydronephrosis

1994 • 197 citations

Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7).

1996 • 189 citations

Murine osteogenic protein (OP-1): High levels of mRNA in kidney

1991 • 184 citations

Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development.

1995 • 180 citations

Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice

1999 • 170 citations

Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney

1999 • 143 citations

Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats with obstructive nephropathy

1996 • 142 citations

Angiotensin II and gene expression in the kidney

1998 • 128 citations

Recovery following relief of unilateral ureteral obstruction in the neonatal rat

1999 • 125 citations

Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines

1992 • 114 citations

Obstructive nephropathy in the neonatal rat is attenuated by epidermal growth factor

1998 • 112 citations

Interstitial inflammation and fibrosis in rats with diet-induced hypercholesterolemia

1996 • 110 citations

Role of angiotensin II in the tubulointerstitial fibrosis of obstructive nephropathy

1995 • 101 citations

The role of lipids in nephrosclerosis and glomerulosclerosis

1994 • 91 citations

Pathogenesis of glomerulonephritis.

1993 • 86 citations

Osteogenic Protein-1 (OP-1) Expression and Processing in Chinese Hamster Ovary Cells: Isolation of a Soluble Complex Containing the Mature and Pro-Domains of OP-1

1994 • 85 citations

UNILATERAL URETERAL OBSTRUCTION IN EARLY DEVELOPMENT ALTERS RENAL GROWTH: DEPENDENCE ON THE DURATION OF OBSTRUCTION

1999 • 84 citations

Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy

1993 • 76 citations

Proliferation of renal interstitial cells following injury induced by ureteral obstruction.

1976 • 72 citations

Effects of IGF-I on renal function in end-stage chronic renal failure

1994 • 65 citations

Signaling mechanisms coupled to the angiotensin receptor of proximal tubular epithelium.

1990 • 62 citations

Role of the renin-angiotensin-aldosterone system in the progression of renal disease: a critical review.

1997 • 58 citations

Osteogenic protein-1 mRNA expression is selectively modulated after acute ischemic renal injury.

1998 • 56 citations

Effects of probucol on renal function in rats with bilateral ureteral obstruction

1990 • 55 citations

Cell apoptosis and proliferation in obstructive uropathy.

1998 • 54 citations

Role of increased glomerular protein traffic in the progression of renal failure.

1997 • 54 citations

Tissue-Specific Regulation of Growth Factors and Clusterin by Angiotensin II

1998 • 50 citations

Osteogenic Protein-1 Is Required for Mammalian Eye Development

1996 • 49 citations

Regulation of renal growth factors and clusterin by AT1 receptors during neonatal ureteral obstruction

1995 • 47 citations

The expression of mRNA for tumour necrosis factor‐α increases in the obstructed kidney of rats soon after unilateral ureteral ligation

1996 • 45 citations

Localization of fibroblast growth factor-2 (basic FGF) and FGF receptor-1 in adult human kidney

1999 • 41 citations

Regulation of angiotensin II AT1 and AT2 receptors in neonatal ureteral obstruction

1997 • 40 citations

Ultrastructural analysis of human proximal tubules and cortical interstitium in chronic renal disease (Hydronephrosis)

1984 • 37 citations

Mediation of immune glomerular injury

1993 • 21 citations

Mediators of Immune Glomerular Injury

1993 • 16 citations

Mechanisms of progressive glomerulosclerosis and tubulointerstitial fibrosis

1998 • 9 citations