Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

1994 • 1,604 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

1990 • 1,211 citations

Mouse Small eye results from mutations in a paired-like homeobox-containing gene

1991 • 1,124 citations

Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 • 1,019 citations

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

1996 • 787 citations

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

1997 • 776 citations

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

1999 • 773 citations

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development

1995 • 662 citations

Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.

1990 • 636 citations

The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis.

1994 • 600 citations

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

1997 • 567 citations

Morphogens, Compartments, and Pattern: Lessons from Drosophila?

1996 • 559 citations

Multistep signaling requirements for pituitary organogenesis in vivo

1998 • 478 citations

Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary

1998 • 388 citations

Forebrain patterning defects in Small eye mutant mice

1996 • 379 citations

Mapping of the early neural primordium in quail-chick chimeras

1985 • 378 citations

Formation of Rathke’s pouch requires dual induction from the diencephalon

1998 • 320 citations

Reciprocal Interactions of Pit1 and GATA2 Mediate Signaling Gradient–Induced Determination of Pituitary Cell Types

1999 • 319 citations

Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain

1997 • 267 citations

Prostate-specific and Androgen-dependent Expression of a Novel Homeobox Gene

1996 • 238 citations

Anterior pituitary development: Short tales from dwarf mice

1992 • 208 citations

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.

1997 • 205 citations

Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon

1997 • 154 citations

Roles of Pax-6 in murine diencephalic development

1997 • 145 citations

A model for the development of the hypothalamic–pituitary axis: transcribing the hypophysis

1999 • 88 citations

Pax6 Is Implicated in Murine Pituitary Endocrine Function

1999 • 45 citations

The gonadotropin-releasing hormone system does not develop in small-eye (Sey) mouse phenotype

1998 • 44 citations

Comparative Development: Seeing eye to eye

1994 • 8 citations