Multistep signaling requirements for pituitary organogenesis in vivo

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

1994 • 1,604 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

1990 • 1,211 citations

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

1995 • 1,175 citations

Embryonic Development and Induction

1939 • 1,175 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1994 • 1,056 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

1997 • 867 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

1996 • 787 citations

Diversity and Pattern in the Developing Spinal Cord

1996 • 714 citations

Wnt signalling required for expansion of neural crest and CNS progenitors

1997 • 669 citations

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development

1995 • 662 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Signalling networks regulating dental development

1997 • 641 citations

Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.

1990 • 636 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation

1997 • 604 citations

Molecular Models for Vertebrate Limb Development

1997 • 592 citations

Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development

1996 • 588 citations

A Role for the Roof Plate and Its Resident TGFβ-Related Proteins in Neuronal Patterning in the Dorsal Spinal Cord

1997 • 575 citations

Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis

1997 • 561 citations

Morphogens, Compartments, and Pattern: Lessons from Drosophila?

1996 • 559 citations

Evidence from normal expression and targeted misexpression that Bone Morphogenetic Protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis

1996 • 480 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

Specification of Pituitary Cell Lineages by the LIM Homeobox Gene Lhx3

1996 • 445 citations

Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene.

1996 • 419 citations

Multistep Control of Pituitary Organogenesis

1997 • 378 citations

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat

1991 • 338 citations

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain

1997 • 326 citations

In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development.

1994 • 314 citations

P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.

1995 • 291 citations

Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke’s pouch of the mouse embryo

1996 • 286 citations

Mapping of the presumptive brain regions in the neural plate of Xenopus laevis

1990 • 277 citations

P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development.

1996 • 270 citations

TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation

1997 • 268 citations

Prostate-specific and Androgen-dependent Expression of a Novel Homeobox Gene

1996 • 238 citations

The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm

1997 • 226 citations

The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo

1988 • 211 citations

Anterior pituitary development: Short tales from dwarf mice

1992 • 208 citations

GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland.

1994 • 186 citations

Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements.

1989 • 176 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 172 citations

The initiation of the limb bud: Growth factors, Hox genes, and retinoids

1995 • 170 citations

Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues

1995 • 154 citations

Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo

1996 • 152 citations

The hypothalamic-pituitary axis; co-development of two organs

1996 • 150 citations

Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression.

1992 • 145 citations

MSX1 inhibits MyoD expression in fibroblast × 10T½ cell hybrids

1995 • 142 citations

Sequence, Genomic Organization, and Expression of the Novel Homeobox Gene Hesx1

1995 • 113 citations

Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland.

1994 • 87 citations

Anterior pituitary cells defective in the cell-autonomous factor, df, undergo cell lineage specification but not expansion

1996 • 86 citations

Somite Differentiation: Sonic signals somites

1995 • 66 citations

Rathke's pouch morphogenesis in the chick embryo

1979 • 54 citations

Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland

1994 • 45 citations

GATA-Binding Proteins Regulate the Human Gonadotropin α-Subunit Gene in the Placenta and Pituitary Gland

1994 • 34 citations