The Etiological Role of Allogeneic Fetal Rejection in Pre‐Eclampsia

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

2003 • 3,707 citations

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

1998 • 2,538 citations

Latest Advances in Understanding Preeclampsia

2005 • 2,482 citations

Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism

1999 • 1,560 citations

THE CLASSIFICATION AND DIAGNOSIS OF THE HYPERTENSIVE DISORDERS OF PREGNANCY: STATEMENT FROM THE INTERNATIONAL SOCIETY FOR THE STUDY OF HYPERTENSION IN PREGNANCY (ISSHP)

2001 • 1,526 citations

The Classification and Diagnosis of the Hypertensive Disorders of Pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)

2001 • 1,321 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells

2002 • 917 citations

Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation

2000 • 733 citations

Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

1999 • 650 citations

Mechanism of interferon-gamma action. Characterization of indoleamine 2,3-dioxygenase in cultured human cells induced by interferon-gamma and evaluation of the enzyme-mediated tryptophan degradation in its anticellular activity.

1988 • 459 citations

Prevention of T cell–driven complement activation and inflammation by tryptophan catabolism during pregnancy

2001 • 425 citations

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

2002 • 408 citations

Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme

1985 • 237 citations

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.

1994 • 207 citations

Decreased plasma tryptophan in pregnancy

1996 • 151 citations

Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures.

1987 • 151 citations

Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes

1994 • 145 citations

Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta

2004 • 134 citations

Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance

2004 • 134 citations

Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection

2000 • 127 citations

Kynurenine Pathway Enzymes in Brain: Responses to Ischemic Brain Injury Versus Systemic Immune Activation

1993 • 116 citations

Localisation of Indoleamine 2,3-dioxygenase and Kynurenine Hydroxylase in the Human Placenta and Decidua: Implications for Role of the Kynurenine Pathway in Pregnancy

2004 • 114 citations

Localization and developmental change of indoleamine 2,3-dioxygenase activity in the human placenta.

1991 • 113 citations

Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment.

1990 • 103 citations

Decreased tryptophan catabolism by placental indoleamine 2,3-dioxygenase in preeclampsia

2003 • 101 citations

Maternal Cytokine Production Patterns in Women with Pre‐eclampsia

2005 • 97 citations

Modulation of cellular tryptophan metabolism in human fibroblasts by transforming growth factor-β: Selective inhibition of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA synthetase gene expression

1998 • 85 citations

Localization of Indoleamine 2,3-Dioxygenase and 4-Hydroxynonenal in Normal and Pre-eclamptic Placentae

2002 • 80 citations

Tryptophan degradation in transplanted tumor cells undergoing rejection.

1988 • 80 citations

Species Differences inl-Tryptophan–Kynurenine Pathway Metabolism: Quantification of Anthranilic Acid and Its Related Enzymes

1998 • 74 citations

The endocrinology of pre‐eclampsia

2002 • 55 citations

Implantation: can immunological parameters of implantation failure be of interest for pre-eclampsia?

2003 • 36 citations