Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

1983 • 1,247 citations

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan.

1984 • 847 citations

Interleukin-4 (IL-4) inhibits secretion of IL-1 beta, tumor necrosis factor alpha, and IL-6 by human monocytes

1990 • 438 citations

Indoleamine 2,3-dioxygenase. Purification and some properties

1978 • 362 citations

Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases.

1990 • 320 citations

Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4.

1988 • 303 citations

Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes.

1988 • 280 citations

IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma.

1989 • 228 citations

Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection.

1979 • 210 citations

Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients.

1986 • 191 citations

Human macrophages degrade tryptophan upon induction by interferon-gamma

1987 • 182 citations

Induction of Tryptophan DegradationIn VitroandIn Vivo: A γ-Interferon-Stimulated Activity

1986 • 181 citations

Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide.

1978 • 172 citations

Interferons and indoleamine 2,3-dioxygenase: Role in antimicrobial and antitumor effects

1989 • 139 citations

Interferon-Induced Indoleamine 2,3-Dioxygenase Activity InhibitsChlamydia psittaciReplication in Human Macrophages

1989 • 136 citations

IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes.

1990 • 134 citations

Differential regulation of IL-1 production in human monocytes by IFN-gamma and IL-4.

1990 • 132 citations

Induction of class I and class II MHC antigen expression on murine bone marrow-derived macrophages by IL-4 (B cell stimulatory factor 1).

1988 • 105 citations

Immune Activation and Decreased Tryptophan in Patients with HIV-1 Infection

1990 • 105 citations

Interleukin-4 induces secretion of CSF for granulocytes and CSF for macrophages by peripheral blood monocytes

1989 • 103 citations

The actions of interferon and antiinflammatory agents on induction of indoleamine 2,3-dioxygenase in human peripheral blood monocytes

1987 • 97 citations

Contrasting effects of interferon-gamma and interleukin-4 on the interleukin-6 activity of stimulated human monocytes.

1990 • 94 citations

Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFN-gamma.

1989 • 81 citations

Transforming growth factor beta downregulates interleukin-1 (IL-1)- induced IL-6 production by human monocytes

1990 • 77 citations

Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.

1993 • 70 citations

Picolinic acid, a catabolite of tryptophan, as the second signal in the activation of IFN-gamma-primed macrophages.

1990 • 69 citations

IL-2 enhances c-fms expression in human monocytes.

1990 • 40 citations

IL-4 inhibits the costimulatory activity of IL-2 or picolinic acid but not of lipopolysaccharide on IFN-gamma-treated macrophages.

1991 • 24 citations