Back to search

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

Data up to Jan 2025

Published2002
Citations408
References30

Total Citations Per Year

Abstract

References (30)

Dendritic cells and the control of immunity

1998 • 14,345 citations

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

1998 • 2,538 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism

1999 • 1,560 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation

2000 • 733 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

1999 • 650 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Prevention of T cell–driven complement activation and inflammation by tryptophan catabolism during pregnancy

2001 • 425 citations

Cells Expressing Indoleamine 2,3-Dioxygenase Inhibit T Cell Responses

2002 • 344 citations

Apoptotic Death of CD8+ T Lymphocytes After Immunization: Induction of a Suppressive Population of Mac-1+/Gr-1+ Cells

1998 • 321 citations

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes

1997 • 292 citations

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

1998 • 274 citations

Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

2002 • 251 citations

Differentiating between Memory and Effector Cd8 T Cells by Altered Expression of Cell Surface O-Glycans

2000 • 207 citations

Indoleamine 2,3-Dioxygenase Expression in Transplanted NOD Islets Prolongs Graft Survival After Adoptive Transfer of Diabetogenic Splenocytes

2002 • 203 citations

Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon gamma.

1995 • 174 citations

T Lymphocyte Tolerance: From Thymic Deletion to Peripheral Control Mechanisms

1998 • 158 citations

Rejection of H-Y Disparate Skin Grafts by Monospecific CD4+ Th1 and Th2 Cells: No Requirement for CD8+ T Cells or B Cells

1998 • 146 citations

CD40 Ligation Ablates the Tolerogenic Potential of Lymphoid Dendritic Cells

2001 • 141 citations

Dendritic cells and prospects for transplantation tolerance

2000 • 98 citations

Dichotomy between naïve and memory CD4+T cell responses to Fas engagement

1999 • 87 citations

The role of T cell apoptosis in transplantation tolerance

2000 • 83 citations

Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells.

1996 • 56 citations

Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or β-globin gene promoters

1994 • 48 citations

Inhibition of collagenase and stromelysin gene expression by interferon-gamma in human dermal fibroblasts is mediated in part via induction of tryptophan degradation.

1995 • 39 citations

Self major histocompatibility complex class I antigens expressed solely in lymphoid cells do not induce tolerance in the CD4+ T cell compartment.

1996 • 18 citations

Effects of different antigenic microenvironments on the course of CD8+ T cell responses in vivo

1996 • 17 citations

Functional Characterization of Jurkat T Cells Rescued from CD95/Fas-Induced Apoptosis through the Inhibition of Caspases

2000 • 13 citations

Cited By (0)

Loading...
Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division (2002) – Immunology | Metascience Observatory Explorer