Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells

Rho GTPases in cell biology

2002 • 4,662 citations

Rho and Rac Take Center Stage

2004 • 1,797 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Signal transduction by G‐proteins, Rho‐kinase and protein phosphatase to smooth muscle and non‐muscle myosin II

2000 • 1,219 citations

Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle

2000 • 599 citations

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.

1996 • 560 citations

Regulation of Cell Polarity and Protrusion Formation by Targeting RhoA for Degradation

2003 • 532 citations

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

2000 • 454 citations

Smooth Muscle Differentiation Marker Gene Expression Is Regulated by RhoA-mediated Actin Polymerization

2001 • 374 citations

S Phase of the Cell Cycle

1989 • 366 citations

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

2002 • 326 citations

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

1990 • 314 citations

Serine Phosphorylation Negatively Regulates RhoA in Vivo

2003 • 307 citations

CNF1 Exploits the Ubiquitin-Proteasome Machinery to Restrict Rho GTPase Activation for Bacterial Host Cell Invasion

2002 • 284 citations

Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle

2001 • 283 citations

[15] Preparation of extracts from higher eukaryotes

1990 • 252 citations

Rho as a Mediator of G Protein-Coupled Receptor Signaling

1999 • 244 citations

Specific Contributions of the Small GTPases Rho, Rac, and Cdc42 to Dbl Transformation

1999 • 177 citations

RhoA Expression Is Controlled by Nitric Oxide through cGMP-dependent Protein Kinase Activation

2003 • 173 citations

Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes

2002 • 163 citations

Cytoskeletal Effects of Rho-Like Small Guanine Nucleotide–Binding Proteins in the Vascular System

2001 • 155 citations

A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets.

1989 • 141 citations

Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes

2002 • 131 citations

Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils.

1991 • 119 citations

The Rac1 C-terminal Polybasic Region Regulates the Nuclear Localization and Protein Degradation of Rac1

2004 • 106 citations

RhoB Is Stabilized by Transforming Growth Factor β and Antagonizes Transcriptional Activation

1998 • 101 citations

Post-translational Processing of RhoA

1997 • 93 citations

cGMP-dependent Protein Kinase Inhibits Serum-response Element-dependent Transcription by Inhibiting Rho Activation and Functions

2002 • 88 citations

Proteasomal Degradation of Cytotoxic Necrotizing Factor 1-Activated Rac

2002 • 87 citations

Sildenafil Prevents Change in RhoA Expression Induced by Chronic Hypoxia in Rat Pulmonary Artery

2003 • 72 citations

Negative Regulation of Rho Signaling by Insulin and Its Impact on Actin Cytoskeleton Organization in Vascular Smooth Muscle Cells

2002 • 66 citations

Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)

2001 • 64 citations

Isoprenylation of RhoB Is Necessary for Its Degradation

2002 • 62 citations

Isotype-specific Degradation of Rac Activated by the Cytotoxic Necrotizing Factor 1

2004 • 48 citations

Effect of extracellular ATP on cytosolic Ca2+ concentration in rat pulmonary artery myocytes

1996 • 42 citations

A NOVEL DETERMINANT IN THE COMPLEX REGULATION OF RhoB EXPRESSION BY THE MEVALONATE PATHWAY

2002 • 15 citations