Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

2006 • 5,923 citations

Final Version of 2009 AJCC Melanoma Staging and Classification

2009 • 4,457 citations

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

2003 • 3,194 citations

The Immunobiology of Cancer Immunosurveillance and Immunoediting

2004 • 2,788 citations

Intraepithelial CD8⁺tumor-infiltrating lymphocytes and a high CD8⁺/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

2005 • 2,226 citations

Tumor-Infiltrating CD8⁺ Lymphocytes Predict Clinical Outcome in Breast Cancer

2011 • 1,287 citations

Model Predicting Survival in Stage I Melanoma Based on Tumor Progression

1989 • 1,235 citations

Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma

1996 • 1,110 citations

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

2009 • 1,000 citations

Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function

2010 • 703 citations

Adoptive cell therapy for the treatment of patients with metastatic melanoma

2009 • 568 citations

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

2007 • 506 citations

Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma

2011 • 429 citations

B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer

2010 • 424 citations

High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

2007 • 403 citations

B cells inhibit induction of T cell-dependent tumor immunity

1998 • 393 citations

“Transcription physiology” of pigment formation in melanocytes: central role of MITF

2010 • 354 citations

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

2009 • 354 citations

Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination

2009 • 334 citations

Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response.

1996 • 319 citations

Inhibitory Effects of B Cells on Antitumor Immunity

2006 • 317 citations

B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice

2010 • 316 citations

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

2011 • 303 citations

Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer

2011 • 288 citations

Tumor-Infiltrating Lymphocytes Predict Sentinel Lymph Node Positivity in Patients With Cutaneous Melanoma

2007 • 286 citations

Predicting five-year outcome for patients with cutaneous melanoma in a population-based study

1996 • 282 citations

Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF

2008 • 258 citations

Failure at the Effector Phase: Immune Barriers at the Level of the Melanoma Tumor Microenvironment

2007 • 232 citations

Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

2008 • 223 citations

Increased rejection of primary tumors in mice lacking B cells: Inhibition of anti-tumor CTL and TH1 cytokine responses by B cells

2005 • 215 citations

Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human melanoma.

2009 • 186 citations

A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma.

2000 • 174 citations

Application of a Filtration- and Isolation-by-Size Technique for the Detection of Circulating Tumor Cells in Cutaneous Melanoma

2010 • 158 citations

B lymphocyte pathology in human colorectal cancer. Experimental and clinical therapeutic effects of partial B cell depletion

2000 • 130 citations

A Prognostic Model for Clinical Stage I Melanoma of the Upper Extremity. The Importance of Anatomic Subsites in Predicting Recurrent Disease

1981 • 122 citations

Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection.

2007 • 105 citations

Sequential Immune Escape and Shifting of T Cell Responses in a Long-Term Survivor of Melanoma

2005 • 94 citations

Imiquimod Enhances IFN-γ Production and Effector Function of T Cells Infiltrating Human Squamous Cell Carcinomas of the Skin

2009 • 91 citations

Tumour-infiltrating lymphocytes in metastatic malignant melanoma and response to interferon alpha treatment

1996 • 89 citations

Helper B Cells Promote Cytotoxic T Cell Survival and Proliferation Independently of Antigen Presentation through CD27/CD70 Interactions

2008 • 85 citations

T-Cell Distribution and Adhesion Receptor Expression in Metastatic Melanoma

2007 • 69 citations

Interferons Induce CXCR3-cognate Chemokine Production by Human Metastatic Melanoma

2010 • 62 citations

CD8 T Cells Activated in Distinct Lymphoid Organs Differentially Express Adhesion Proteins and Coexpress Multiple Chemokine Receptors

2010 • 61 citations

Antitumor Immunity at Work in a Melanoma Patient

1999 • 48 citations

Surmounting Tumor-induced Immune Suppression by Frequent Vaccination or Immunization in the Absence of B Cells

2008 • 39 citations

Collapse of the CD27+ B-Cell Compartment Associated with Systemic Plasmacytosis in Patients with Advanced Melanoma and Other Cancers

2009 • 37 citations

Plasma Cells within the Infiltrate of Primary Cutaneous Malignant Melanoma of the Skin

1987 • 27 citations

Prediction of lymph node metastases from the histologic features of primary cutaneous malignant melanomas.

1984 • 17 citations

Abstract 958: Treatment with a selective inhibitor of BRAFV600E increases melanocyte antigen expression and CD8 T cell infiltrate in tumors of patients with metastatic melanoma

2011 • 12 citations

A prognostic model for clinical stage I melanoma of the upper extremity

1982 • 9 citations

Protective effect of a brisk tumor infiltrating lymphocyte infiltrate in melanoma: An EORTC melanoma group study

2007 • 4 citations