High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer
Data up to Jan 2025
Total Citations Per Year
Abstract
References (53)
Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
2003 • 6,072 citations
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
2004 • 4,872 citations
Papillomaviruses and cancer: from basic studies to clinical application
2002 • 3,873 citations
Prevalence of Human Papillomavirus in Cervical Cancer: a Worldwide Perspective
1995 • 3,371 citations
Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
2003 • 3,194 citations
Intraepithelial CD8+tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
2005 • 2,226 citations
Papillomavirus infections — a major cause of human cancers
1996 • 1,536 citations
CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.
1998 • 1,175 citations
Chapter 1: Human Papillomavirus and Cervical Cancer--Burden and Assessment of Causality
2003 • 818 citations
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
2006 • 677 citations
The Expression of the Regulatory T Cell–Specific Forkhead Box Transcription Factor FoxP3 Is Associated with Poor Prognosis in Ovarian Cancer
2005 • 494 citations
A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive.
2000 • 314 citations
Human Papillomavirus Type 16-Positive Cervical Cancer Is Associated with Impaired CD4+ T-Cell Immunity against Early Antigens E2 and E6
2004 • 311 citations
Increased Intratumor Vα24-Positive Natural Killer T Cells: A Prognostic Factor for Primary Colorectal Carcinomas
2005 • 262 citations
Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells
2003 • 232 citations
Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis
2004 • 214 citations
Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.
2003 • 211 citations
Intratumoral CD8+ T Lymphocytes as a Prognostic Factor of Survival in Endometrial Carcinoma
2004 • 209 citations
Infiltration of cervical cancer tissue with human papilloma virus-specific cytotoxic T-lymphocytes
1997 • 196 citations
Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.
1996 • 180 citations
Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX? adjuvant in women with cervical intraepithelial neoplasia
2004 • 178 citations
Immunological and clinical responses in women with vulval intraepithelial neoplasia vaccinated with a vaccinia virus encoding human papillomavirus 16/18 oncoproteins.
2003 • 171 citations
Vaccinia-expressed human papillomavirus 16 and 18 e6 and e7 as a therapeutic vaccination for vulval and vaginal intraepithelial neoplasia.
2003 • 168 citations
Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects.
2002 • 152 citations
Natural T-helper immunity against human papillomavirus type 16 (hpv16) e7-derived peptide epitopes in patients with hpv16-positive cervical lesions: Identification of 3 human leukocyte antigen class ii-restricted epitopes
2001 • 145 citations
Immunological Responses in Women with Human Papillomavirus Type 16 (HPV-16)-Associated Anogenital Intraepithelial Neoplasia Induced by Heterologous Prime-Boost HPV-16 Oncogene Vaccination
2004 • 127 citations
Histopathologic parameters of prognosis in cervical cancer - a review
2004 • 107 citations
Human papillomavirus detection in paraffin-embedded cervical carcinomas and metastases of the carcinomas by the polymerase chain reaction.
1989 • 91 citations
Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia
2000 • 87 citations
CD8hi+CD57+ T lymphocytes are enriched in antigen-specific T cells capable of down-modulating cytotoxic activity
1998 • 81 citations
Infiltration by immunocompetent cells in early stage invasive carcinoma of the uterine cervix: a prognostic study
1996 • 80 citations
Detection of human papillomavirus type 18 E6 and E7‐specific CD4+ T‐helper 1 immunity in relation to health versus disease
2005 • 76 citations
Infiltration of cervical cancer tissue with human papilloma virus-specific cytotoxic T-lymphocytes
1997 • 71 citations
Proliferative T cell responses to the human papillomavirus type 16 E7 protein in women with cervical dysplasia and cervical carcinoma and in healthy individuals
1996 • 68 citations
Isolation and characterization of tumor‐infiltrating lymphocytes from cervical carcinoma
1994 • 66 citations
Adjuvant radiotherapy following radical hysterectomy for patients with early-stage cervical carcinoma (1984-1996)
1999 • 57 citations
CD4+ Tumor-Infiltrating Lymphocytes in Cervical Cancer Recognize HLA-DR-Restricted Peptides Provided by Human Papillomavirus-E7
1999 • 50 citations
The case for completing the lymphadenectomy when positive lymph nodes are found during radical hysterectomy for cervical carcinoma
2000 • 50 citations
Identification of a Conserved Universal Th Epitope in HIV-1 Reverse Transcriptase That Is Processed and Presented to HIV-Specific CD4+ T Cells by at Least Four Unrelated HLA-DR Molecules
1999 • 48 citations
Human Papillomavirus Type 33 E7 Peptides Presented by HLA-DR*0402 to Tumor-Infiltrating T Cells in Cervical Cancer
2000 • 38 citations
Lymphocyte-infiltrated FIGO Stage IIB squamous cell carcinoma of the cervix is a prominent factor for disease-free survival.
1999 • 37 citations
A basal membrane-like structure surrounding tumour nodules may prevent intraepithelial leucocyte infiltration in colorectal cancer
2003 • 35 citations
The case for completing the lymphadenectomy when positive lymph nodes are found during radical hysterectomy for cervical carcinoma
2000 • 30 citations
The status of HPV16-specific T-cell reactivity in health and disease as a guide to HPV vaccine development
2002 • 30 citations
Histopathologic parameters of prognosis in cervical cancer – a review
2004 • 28 citations
Magnitude and polarization of P53‐specific T‐helper immunity in connection to leukocyte infiltration of colorectal tumors
2003 • 28 citations
Induction of tumor-specific cytotoxicity in tumor infiltrating lymphocytes by HPV16 and HPV18 E7-pulsed autologous dendritic cells in patients with cancer of the uterine cervix
2003 • 27 citations
Rapid enrichment of human papillomavirus (HPV)‐specific polyclonal T cell populations for adoptive immunotherapy of cervical cancer
2004 • 23 citations
Correlation of three-dimensional tumor volumetry with cervical cancer prognostic parameters.
2002 • 20 citations
Four-color staining combining fluorescence and brightfield microscopy for simultaneous immune cell phenotyping and localization in tumor tissue sections
2005 • 15 citations
Adjuvant therapy after primary surgery for stage I-IIA carcinoma of the cervix.
1996 • 15 citations
CTL-mediated immunity against human papillomavirus type 16 E7-encoded epitopes presented by HLA-A2
1997 • 6 citations
Deleted Work
1955 • 0 citations
Cited By (0)
No citing papers found in database