Tumor-Infiltrating CD8+ Lymphocytes Predict Clinical Outcome in Breast Cancer
Data up to Jan 2025
Total Citations Per Year
Abstract
References (53)
Regression Models and Life-Tables
1992 • 27,454 citations
pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up
1991 • 5,979 citations
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 • 5,923 citations
Cancer immunoediting: from immunosurveillance to tumor escape
2002 • 4,911 citations
Tissue microarrays for high-throughput molecular profiling of tumor specimens
1998 • 4,104 citations
Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
2003 • 3,194 citations
X-Tile
2004 • 3,150 citations
The Three Es of Cancer Immunoediting
2004 • 2,781 citations
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
2001 • 2,658 citations
Intraepithelial CD8+tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
2005 • 2,226 citations
The tumor microenvironment and its role in promoting tumor growth
2008 • 2,152 citations
Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer
2009 • 1,637 citations
Tumor Antigens Recognized by T Lymphocytes
1994 • 1,238 citations
Prognostic markers in triple‐negative breast cancer
2006 • 1,223 citations
The Nottingham prognostic index in primary breast cancer
1992 • 1,051 citations
In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer
2009 • 880 citations
Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
2006 • 829 citations
Validation of Tissue Microarray Technology in Breast Carcinoma
2000 • 800 citations
Reporting Recommendations for Tumor Marker Prognostic Studies
2005 • 760 citations
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity.
2001 • 625 citations
High‐throughput protein expression analysis using tissue microarray technology of a large well‐characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
2005 • 597 citations
Expression of luminal and basal cytokeratins in human breast carcinoma
2004 • 593 citations
Molecular evolution of breast cancer
2005 • 512 citations
CD8+ Tumor-Infiltrating Lymphocytes Together with CD4+ Tumor-Infiltrating Lymphocytes and Dendritic Cells Improve the Prognosis of Patients with Pancreatic Adenocarcinoma
2003 • 506 citations
Pathological prognostic factors in breast cancer. II. Histological type. Relationship with survival in a large study with long‐term follow‐up
1992 • 485 citations
Decreased antigen presentation by dendritic cells in patients with breast cancer.
1997 • 439 citations
Predominant infiltration of macrophages and CD8+T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer
2008 • 359 citations
Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation
2006 • 317 citations
Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes?
2007 • 294 citations
Pathological prognostic factors in breast cancer. III. Vascular invasion: relationship with recurrence and survival in a large study with long‐term follow‐up
1994 • 284 citations
Lymphocyte infiltrates as a prognostic variable in female breast cancer
1992 • 283 citations
Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance
2006 • 194 citations
Study of tumor infiltrating lymphocytes and transforming growth factor-β as prognostic factors in breast carcinoma
1997 • 182 citations
Quantitative In situ Analysis of β-Catenin Expression in Breast Cancer Shows Decreased Expression Is Associated with Poor Outcome
2006 • 179 citations
An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer
2010 • 170 citations
Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor
2000 • 161 citations
Expression of BRCA1 protein in breast cancer and its prognostic significance
2008 • 143 citations
Identification of lymphocyte subpopulations in human breast cancer tissue and its significance: An immunoperoxidase study with anti-human t- and b-cell sera
1982 • 124 citations
Review Article The immunology and immunotherapy of breast cancer: an update
1999 • 111 citations
Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer
1994 • 109 citations
Angiogenesis and inflammation in invasive carcinoma of the breast.
1997 • 98 citations
Different patterns of inflammation and prognosis in invasive carcinoma of the breast
2006 • 87 citations
The immunophenotype and activation status of the lymphocytic infiltrate in human breast cancers, the role of the major histocompatibility complex in cell-mediated immune mechanisms, and their association with prognostic indicators
2003 • 66 citations
Cell-mediated immunity to tumor-associated antigens is a better predictor of survival in early stage breast cancer than stage, grade or lymph node status
2000 • 58 citations
Prognostic Significance of Necrosis, Elastosis, Fibrosis and Inflammatory Cell Reaction in Operable Breast Cancer
1995 • 46 citations
Immunological enhancement of breast cancer
1997 • 45 citations
Biological markers and breast cancer. A multiparametric study. II: Depressed immune competence
1982 • 43 citations
Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: Clinical implications
2006 • 41 citations
Vaccine immunotherapy in breast cancer treatment: promising, but still early
2007 • 39 citations
Antigen Recognition by B-cell and T-cell Receptors
2001 • 31 citations
Quantifying tumour-infiltrating lymphocyte subsets: A practical immuno-histochemical method
2007 • 29 citations
Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce “danger signals”
2005 • 27 citations
Augmenting the Potency of Breast Cancer Vaccines: Combined Modality Immunotherapy
2004 • 20 citations