RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

1991 • 1,489 citations

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11

1996 • 1,296 citations

Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human y chromosome long arm

1976 • 980 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

SR proteins and splicing control.

1996 • 668 citations

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

1993 • 663 citations

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

1994 • 622 citations

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

1996 • 559 citations

A novel genetic system to detect protein-protein interactions

1991 • 532 citations

A Y chromosome gene family with RNA-binding protein homology: Candidates for the azoospermia factor AZF controlling human spermatogenesis

1993 • 515 citations

Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene

1996 • 504 citations

Microdeletions in the Y Chromosome of Infertile Men

1997 • 497 citations

Sex in flies: the splice of life

1989 • 468 citations

Molecular mechanisms of male germ cell differentiation

1998 • 429 citations

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

1994 • 407 citations

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

1987 • 406 citations

Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

1997 • 394 citations

A target for Src in mitosis

1994 • 361 citations

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

1998 • 334 citations

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

1994 • 325 citations

The SR protein family: pleiotropic functions in pre-mRNA splicing

1996 • 259 citations

The Neuronal RNA Binding Protein Nova-1 Recognizes Specific RNA Targets In Vitro and In Vivo

1997 • 258 citations

Expression of RBM in the nuclei of human germ cells is dependent on a critical region of the Y chromosome long arm

1997 • 256 citations

Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

1999 • 251 citations

Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities

1998 • 230 citations

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.

1996 • 228 citations

The Polypyrimidine Tract Binding Protein Binds Upstream of Neural Cell-Specific c-src Exon N1 To Repress the Splicing of the Intron Downstream

1997 • 214 citations

A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.

1997 • 213 citations

Human Tra2 Proteins Are Sequence-Specific Activators of Pre-mRNA Splicing

1998 • 212 citations

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors.

1994 • 199 citations

Pathways for selection of 5′ splice sites by U1 snRNPs and SF2/ASF.

1993 • 192 citations

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

1997 • 192 citations

Multiple Distinct Splicing Enhancers in the Protein-Coding Sequences of a Constitutively Spliced Pre-mRNA

1999 • 191 citations

Self-Association of the Single-KH-Domain Family Members Sam68, GRP33, GLD-1, and Qk1: Role of the KH Domain

1997 • 186 citations

The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2

1994 • 182 citations

Specificity and Determinants of Sam68 RNA Binding

1997 • 161 citations

Synergistic interactions between two distinct elements of a regulated splicing enhancer.

1995 • 156 citations

Differential Binding of Heterogeneous Nuclear Ribonucleoproteins to mRNA Precursors prior to Spliceosome Assembly In Vitro

1992 • 142 citations

hnRNP G: sequence and characterization of a glycosylated RNA-binding protein

1993 • 141 citations

A human homologue of the Drosophila sex determination factor transformer-2 has conserved splicing regulatory functions.

1996 • 131 citations

Protein phosphorylation and the nuclear organization of pre-mRNA splicing

1997 • 117 citations

Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB

1999 • 116 citations

Protein Phosphorylation Plays an Essential Role in the Regulation of Alternative Splicing and Sex Determination in Drosophila

1998 • 115 citations

Regulation of pre-mRNA splicing in metazoa

1997 • 110 citations

A human candidate spermatogenesis gene, RBM1, is conserved and amplified on the marsupial Y chromosome

1997 • 108 citations

T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA- binding protein implicated in spermatogenesis

1999 • 106 citations

dissatisfaction , a gene involved in sex-specific behavior and neural development of Drosophila melanogaster

1997 • 103 citations

SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1

1999 • 95 citations

Dynamic changes in the subnuclear organisation of pre-mRNA splicing proteins and RBM during human germ cell development

1998 • 87 citations

RNA processing : a practical approach

1994 • 86 citations

The roles of RNA-binding proteins in spermatogenesis and male Infertility

1999 • 78 citations

Molecular Cloning of htra2-beta-1 and htra2-beta-2, Two Human Homologs oftra-2Generated by Alternative Splicing

1997 • 76 citations

A conserved epitope on a subset of SR proteins defines a larger family of Pre-mRNA splicing factors.

1995 • 73 citations

An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells

1996 • 71 citations

Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing

1999 • 59 citations

Structure and Organization of theRBMYGenes on the Human Y Chromosome: Transposition and Amplification of an Ancestral AutosomalhnRNPGGene

1998 • 57 citations

The Developmental Consequences of Alternate Splicing in Sex Determination and Differentiation inDrosophila

1995 • 54 citations

Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis

1997 • 51 citations

The molecular genetics of male infertility

1997 • 50 citations

Alternative Splicing of a Human α-Tropomyosin Muscle-Specific Exon: Identification of Determining Sequences

1992 • 47 citations

The mammalian Y chromosome: a new perspective

1998 • 36 citations

Autoregulation of transformer-2 Alternative Splicing Is Necessary for Normal Male Fertility in Drosophila

1998 • 35 citations

Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2

1996 • 30 citations

Analysis of the functional specificity of RS domains invivo

1998 • 28 citations

Human Y Chromosome Deletions in Yq11 and Male Fertility

1997 • 23 citations

β-globin transcripts carrying a single intron with three adjacent nucleotides of 5′ exon are efficiently splicedin vitroirrespective of intron position or surrounding exon sequences

1990 • 17 citations

Evolution of mammalian HNRPG and its relationship with the putative azoospermia factor RBM

1998 • 16 citations

Splicing of mRNA precursors in mammalian cells

1994 • 15 citations