Stimulated initiation of mitogen-activated protein kinase phosphatase-1 (MKP-1) gene transcription involves the synergistic action of multiple cis-acting elements in the proximal promoter

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers

1999 • 1,593 citations

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling

2000 • 796 citations

Dual specificity phosphatases: a gene family for control of MAP kinase function

2000 • 791 citations

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

1992 • 647 citations

MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network

2002 • 647 citations

Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking

1997 • 610 citations

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1998 • 496 citations

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

2001 • 466 citations

Reduced MAP Kinase Phosphatase-1 Degradation After p42/p44 ^MAPK -Dependent Phosphorylation

1999 • 414 citations

Genomic Sequencing and Methylation Analysis by Ligation Mediated PCR

1989 • 408 citations

MAPK-regulated transcription: a continuously variable gene switch?

2002 • 404 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Transactivation joins multiple tracks to the ERK/MAPK cascade

2003 • 381 citations

Integration of calcium and RAS signalling

2002 • 375 citations

Signaling routes to CREM and CREB: plasticity in transcriptional activation

1999 • 304 citations

Sp3 Is a Bifunctional Transcription Regulator with Modular Independent Activation and Repression Domains

1997 • 284 citations

A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure

1998 • 277 citations

Three Functional Classes of Transcriptional Activation Domains

1996 • 267 citations

RNA polymerase II elongation through chromatin

2000 • 244 citations

cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

1992 • 234 citations

An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.

1996 • 224 citations

Control of elongation by RNA polymerase II

2000 • 206 citations

Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

2001 • 202 citations

Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer

2003 • 184 citations

Transcriptional Induction of MKP-1 in Response to Stress Is Associated with Histone H3 Phosphorylation-Acetylation

2001 • 175 citations

Promoter-associated Pausing in Promoter Architecture and Postinitiation Transcriptional Regulation

1998 • 173 citations

Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene.

1994 • 171 citations

The Dual-Specificity Phosphatase MKP-1 Limits the Cardiac Hypertrophic Response In Vitro and In Vivo

2001 • 163 citations

RNA polymerase II C-terminal domain required for enhancer-driven transcription

1995 • 155 citations

Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - a potential mechanism

2001 • 150 citations

Extracellular signals and scores of phosphatases: All roads lead to MAP kinase

2000 • 134 citations

Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression Is Induced by Low Oxygen Conditions Found in Solid Tumor Microenvironments

1999 • 130 citations

Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity

2001 • 120 citations

Dual Roles of RNA Helicase A in CREB-Dependent Transcription

2001 • 110 citations

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

2000 • 108 citations

Calcineurin Enhances MAPK Phosphatase-1 Expression and p38 MAPK Inactivation in Cardiac Myocytes

2001 • 90 citations

Inhibition of the Expression of Mitogen-activated Protein Phosphatase-1 Potentiates Apoptosis Induced by Tumor Necrosis Factor-α in Rat Mesangial Cells

1998 • 84 citations

Transcriptional Induction of Mitogen-activated Protein Kinase Phosphatase 1 by Retinoids

2002 • 64 citations

The Chromatin Structure of the Dual c-myc Promoter P1/P2 Is Regulated by Separate Elements

2001 • 63 citations

Stimulated initiation of mitogen-activated protein kinase phosphatase-1 (MKP-1) gene transcription involves the synergistic action of multiple cis-acting elements in the proximal promoter

2004 • 54 citations

Synergistic activation of the mkp‐1 gene by protein kinase A signaling and USF, but not c‐Myc

2000 • 50 citations

MAP Kinase Phosphatase-1 Gene Transcription in Rat Neuroendocrine Cells Is Modulated by a Calcium-sensitive Block to Elongation in the First Exon

2001 • 48 citations

Regulation of c- fos expression by RNA polymerase elongation competence 1 1Edited by K. Yamamoto

1998 • 39 citations

Sp3 Represses Gene Expression via the Titration of Promoter-specific Transcription Factors

2002 • 36 citations

Ligation-mediated PCR: Applications to genomic footprinting

1991 • 35 citations

RNA polymerase II promoter-proximal pausing upregulates c-fos gene expression

2000 • 26 citations

Essential Contribution of Intron Sequences to Ca<sup>2+</sup>-Dependent Activation of <i>c-fos</i> Transcription in Pituitary Cells

2000 • 25 citations

Variable pause positions of RNA polymerase II lie proximal to the c-mycpromoter irrespective of transcriptional activity

1995 • 24 citations

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

2000 • 24 citations

The coactivator dTAF _II 110/hTAF _II 135 is sufficient to recruit a polymerase complex and activate basal transcription mediated by CREB

2001 • 20 citations

MAP KINASE PHOSPHATASE-1 GENE EXPRESSION AND REGULATION IN NEUROENDOCRINE CELLS

2002 • 9 citations