An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Cell lines derived from late embryonic stages of Drosophila melanogaster

1972 • 1,215 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Expression and regulation of Escherichia coli lacZ gene fusions in mammalian cells.

1983 • 471 citations

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism.

1991 • 437 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Transient expression of genes introduced into cultured cells of Drosophila.

1983 • 370 citations

Different members of the Sp1 multigene family exert opposite transcritional regulation of the long terminal repeat of HIV-1

1994 • 231 citations

CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity.

1995 • 230 citations

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.

1993 • 223 citations

The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function.

1991 • 217 citations

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression.

1995 • 212 citations

Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: Differences between v- and c-Jun

1990 • 212 citations

Functional Analyses of the Transcription Factor Sp4 Reveal Properties Distinct from Sp1 and Sp3

1995 • 208 citations

Sp1 Trans-Activation of Cell Cycle Regulated Promoters Is Selectively Repressed by Sp3

1995 • 193 citations

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.

1994 • 138 citations

Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ

1995 • 134 citations

Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins.

1995 • 124 citations

Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain.

1996 • 118 citations

Cloning of GT Box-Binding Proteins: A Novel Spl Multigene Family Regulating T-Cell Receptor Gene Expression

1992 • 114 citations

Carboxy-terminal elements of c-Myb negatively regulate transcriptional activation in cis and in trans.

1992 • 103 citations

The Uteroglobin Promoter Contains a Noncanonical Estrogen Responsive Element

1990 • 98 citations

Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor.

1993 • 94 citations

The promoter activity of long terminal repeats of the HERV-H family of human retrovirus-like elements is critically dependent on Sp1 family proteins interacting with a GC/GT box located immediately 3' to the TATA box

1996 • 92 citations

Sp3 Represses Transcription When Tethered to Promoter DNA or Targeted to Promoter Proximal RNA

1996 • 83 citations

v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor

1991 • 81 citations

The use of gel electrophoresis to detect and study nucleic acid— protein interactions

1986 • 75 citations

A Novel Repression Module, an Extensive Activation Domain, and a Bipartite Nuclear Localization Signal Defined in the Immediate-Early Transcription Factor Egr-1

1993 • 66 citations

The activation domain of a basic helix-loop-helix protein is masked by repressor interaction with domains distinct from that required for transcription regulation.

1994 • 49 citations

Cell type-specific trans-activation by the B-myb gene product: requirement of the putative cofactor binding to the C-terminal conserved domain.

1995 • 43 citations

An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif.

1995 • 42 citations

Transcriptional Activity of the Zinc Finger Protein NGFI-A Is Influenced by Its Interaction with a Cellular Factor

1993 • 21 citations