Ligand Activation Domain of Human Orphan Growth Hormone (GH) Secretagogue Receptor (GHS-R) Conserved from Pufferfish to Humans

[19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors

1995 • 2,811 citations

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

1996 • 2,048 citations

Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused Acromegaly

1982 • 1,263 citations

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

1997 • 1,137 citations

Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour

1982 • 1,092 citations

Sexual Dimorphism in the Control of Growth Hormone Secretion*

1985 • 749 citations

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

1984 • 652 citations

Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome

1993 • 579 citations

Peptidomimetic Regulation of Growth Hormone Secretion

1997 • 520 citations

Receptor for Motilin Identified in the Human Gastrointestinal System

1999 • 396 citations

A Nonpeptidyl Growth Hormone Secretagogue

1993 • 345 citations

Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors

1997 • 341 citations

Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue.

1995 • 323 citations

Growth Hormone (GH)-Releasing Peptide Stimulates GH Release in Normal Men and Acts Synergistically with GH-Releasing Hormone*

1990 • 315 citations

Cloning and Characterization of Two Human G Protein-Coupled Receptor Genes (GPR38 and GPR39) Related to the Growth Hormone Secretagogue and Neurotensin Receptors

1997 • 289 citations

Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.

1993 • 272 citations

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects.

1996 • 256 citations

Evolution of Cellular DNA Content in Teleost Fishes

1968 • 211 citations

Design, Synthesis, and Biological Activity of Peptides which Release Growth Hormone in Vitro*

1981 • 210 citations

Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat

1997 • 190 citations

Molecular architecture of G protein-coupled receptors

1996 • 178 citations

Daytime Pulsatile Growth Hormone Secretion during Childhood and Adolescence*

1982 • 161 citations

Growth Hormone-Releasing Hormone: Synthesis and Signaling

1995 • 159 citations

Comparative sequence analysis of the human and pufferfish Huntington's disease genes

1995 • 138 citations

Structural Requirements for the Activation of the Human Growth Hormone Secretagogue Receptor by Peptide and Nonpeptide Secretagogues

1998 • 124 citations

Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

1996 • 120 citations

Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus.

1993 • 106 citations

A New Orphan Receptor Involved in Pulsatile Growth Hormone Release

1999 • 72 citations

Peptidomimetic Growth Hormone Secretagogues. Design Considerations and Therapeutic Potential

1998 • 69 citations

Somatostatin: A Physiological Role in the Regulation of Growth Hormone Secretion in the Adolescent Male Baboon*

1978 • 64 citations

Cloning and Characterization of a Human and Murine T-Cell Orphan G-Protein-Coupled Receptor Similar to the Growth Hormone Secretagogue and Neurotensin Receptors

1998 • 63 citations

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study.

1996 • 54 citations

Analysis of the dopamine receptor family in the compact genome of the puffer fish Fugu rubripes

1995 • 53 citations

Genomic structure and sequence of the fugu rubripes glucose-6-phosphate dehydrogenase gene (G6PD)

1995 • 53 citations

Something fishy in the rat brain: molecular genetics of the hypothalamo-neurohypophysial system

1998 • 36 citations

1-[2(R)-(2-Amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3- benzylpiperidine-3(S)-carboxylic Acid Ethyl Ester (L-163,540): A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue

1998 • 35 citations

Genomic Structure and Nucleotide Sequence of the p55 Gene of the Puffer Fish Fugu rubripes

1995 • 33 citations

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study

1996 • 31 citations

Effects of Growth Hormone Secretagogues on Prolactin Release in Anesthetized Dwarf (dw/dw) Rats*

1998 • 28 citations

One Armed PCR (OA-PCR): Amplification of Genomic DNA from a Single Primer Domain

1994 • 15 citations

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and non-peptide secretagogues

1998 • 15 citations

Structure, Function, and Regulation of the Pituitary Receptor for Growth Hormone Releasing Hormone

1996 • 12 citations