Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

1996 • 2,048 citations

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

1997 • 1,137 citations

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

1984 • 652 citations

An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

1985 • 523 citations

Molecular basis of the little mouse phenotype and Implications for cell type-specific growth

1993 • 477 citations

The Regulation of Growth Hormone Secretion

2015 • 440 citations

Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors

1997 • 341 citations

Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone.

1992 • 327 citations

The Synergistic Effects of His-D-Trp-Ala-Trp-D-Phe- Lys-NH₂on Growth Hormone (GH)-Releasing Factor- Stimulated GH Release and Intracellular Adenosine 3',5'-Monophosphate Accumulation in Rat Primary Pituitary Cell Culture

1989 • 298 citations

Induction of c-fos Messenger Ribonucleic Acid in Neuropeptide Y and Growth Hormone (GH)-Releasing Factor Neurons in the Rat Arcuate Nucleus Following Systemic Injection of the GH Secretagogue, GH-Releasing Peptide-6*

1997 • 285 citations

Growth hormone-deficient dwarfism in the rat: a new mutation

1988 • 239 citations

Identification of a new G-protein-linked receptor for growth hormone secretagogues.

1996 • 199 citations

Structure-Activity Relationships of a Synthetic Pentapeptide that Specifically Releases Growth Hormonein Vitro*

1980 • 197 citations

Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level.

1995 • 189 citations

Systemic administration of growth hormone-releasing peptide activates hypothalamic arcuate neurons

1993 • 182 citations

Growth hormone (GH)-releasing hormone secretion is stimulated by a new GH-releasing hexapeptide in sheep.

1994 • 163 citations

Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites

1989 • 148 citations

Desensitization studies using perifused rat pituitary cells show that growth hormone-releasing hormone and His-d-Trp-Ala-Trp-d-Phe-Lys-NH2 stimulate growth hormone release through distinct receptor sites

1991 • 146 citations

Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons.

1992 • 145 citations

Evidence for a Role of Protein Kinase-C in His-D-Trp Ala-Trp-D-Phe-Lys-NH₂-Induced Growth Hormone Release from Rat Primary Pituitary Cells

1991 • 136 citations

Receptor-Associated Resistance to Growth Hormone-Releasing Factor in Dwarf "Little" Mice

1986 • 133 citations

Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat.

1996 • 123 citations

The Effects of a Growth Hormone‐Releasing Peptide and Growth Hormone‐Releasing Factor in Conscious and Anaesthetized Rats

1989 • 123 citations

Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

1996 • 120 citations

Growth Hormone-Releasing Peptide-6 Stimulates Sleep, Growth Hormone, ACTH and Cortisol Release in Normal Man

1995 • 116 citations

Central Actions of Peptide and Non-Peptide Growth Hormone Secretagogues in the Rat

1995 • 116 citations

Intracerebroventricular growth-hormone-releasing peptide-6 stimulates eating without affecting plasma growth hormone responses in rats

1995 • 114 citations

Activation of the Hypothalamo-Pituitary-Adrenal Axis by the Growth Hormone (GH) Secretagogue, GH-Releasing Peptide-6, in Rats

1997 • 104 citations

Growth hormone receptor gene is expressed in neuropeptide Y neurons in hypothalamic arcuate nucleus of rats.

1996 • 102 citations

Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585

1996 • 101 citations

Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons

1992 • 101 citations

The Regulation of Growth Hormone Secretion

1999 • 93 citations

Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action

1995 • 88 citations

Combined Autoradiographic and Immunohistochemical Evidence for an Association of Somatostatin Binding Sites with Growth Hormone‐Releasing Factor‐Containing Nerve Cell Bodies in the Rat Arcuate Nucleus

1989 • 78 citations

Growth hormone secretagogues: characterization, efficacy, and minimal bioactive conformation.

1995 • 75 citations

Hypothalamic Interconnections of Somatostatin and Growth Hormone Releasing Factor Neurons

1989 • 74 citations

Atypical Growth Hormone Releasing Peptides

1994 • 70 citations

Growth Hormone II: Basic and Clinical Aspects

2011 • 64 citations

Growth hormone-releasing hormone and somatostatin concentrations in the hypophysial portal blood of conscious sheep during the infusion of growth hormone-releasing peptide-6

1996 • 63 citations

Hypothalamic GH receptor gene expression in the rat: effects of altered GH status

1995 • 55 citations

Differential regulation of the growth hormone receptor gene: effects of dexamethasone and estradiol.

1996 • 55 citations

The effects of GH-releasing peptide-6 (GHRP-6) and GHRP-2 on intracellular adenosine 3′,5′-monophosphate (cAMP) levels and GH secretion in ovine and rat somatotrophs

1996 • 55 citations

Growth hormone releasing peptide (GHRP-6) stimulates phosphatidylinositol (PI) turnover in human pituitary somatotroph cells

1995 • 53 citations

GH-deficient dw/dw rats and lit/lit mice show increased Fos expression in the hypothalamic arcuate nucleus following systemic injection of GH-releasing peptide-6

1995 • 50 citations

Repeat administration of the GH secretagogue MK-0677 increases and maintains elevated IGF-I levels in beagles

1997 • 48 citations

Protein kinase C-dependent growth hormone releasing peptides stimulate cyclic adenosine 3',5'-monophosphate production by human pituitary somatotropinomas expressing gsp oncogenes: evidence for crosstalk between transduction pathways.

1996 • 46 citations

Growth Hormone-Releasing Peptide (GHRP) binding to porcine anterior pituitary and hypothalamic membranes

1992 • 39 citations

Sex Differences in Growth Hormone (GH) Secretion by Rats Administered GH-Releasing Hexapeptide

1991 • 35 citations

Growth Hormone-Releasing Peptides: Clinical and Basic Aspects

1996 • 32 citations

Pituitary Hormones as Neurotrophic Signals: Anomalous Hypophysiotrophic Neuron Differentiation in Hypopituitary Dwarf Mice

1994 • 32 citations

Effect of Intravenous or Intracerebroventricular Injections of His-D-Trp-Ala-Trp-D-Phe-Lys-NH<sub>2</sub> on GH Release in Conscious, Freely Moving Male Rats

1996 • 21 citations

Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue

1995 • 18 citations

Effects of Growth Hormone Releasing Peptides on Stimulated Growth Hormone Secretion in Old Rats

1994 • 11 citations

Interactions between neuropeptide Y and growth hormone receptor gene transcripts in the arcuate nucleus

1996 • 3 citations