Structure, Function, and Regulation of the Pituitary Receptor for Growth Hormone Releasing Hormone

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours

1989 • 1,405 citations

Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused Acromegaly

1982 • 1,263 citations

A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide

1991 • 1,230 citations

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

1990 • 1,211 citations

Differential signal transduction by five splice variants of the PACAP receptor

1993 • 1,185 citations

Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour

1982 • 1,092 citations

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

1992 • 880 citations

Sequence Alignment of the G-Protein Coupled Receptor Superfamily

1992 • 847 citations

Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide

1992 • 752 citations

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

1984 • 652 citations

Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor Family

1989 • 647 citations

Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain.

1993 • 485 citations

Structural basis of β‐adrenergic receptor function

1989 • 480 citations

Molecular basis of the little mouse phenotype and Implications for cell type-specific growth

1993 • 477 citations

Expression Cloning of an Adenylate Cyclase-Coupled Calcitonin Receptor

1991 • 458 citations

A Mutation in the POU-Homeodomain of Pit-1 Responsible for Combined Pituitary Hormone Deficiency

1992 • 446 citations

Growth Hormone-Releasing Hormone*

1986 • 427 citations

Molecular cloning and expression of a cDNA encoding the secretin receptor.

1991 • 415 citations

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

1993 • 414 citations

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

1993 • 399 citations

Expression cloning and signaling properties of the rat glucagon receptor

1993 • 393 citations

Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor.

1993 • 379 citations

Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth

1992 • 330 citations

Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro.

1986 • 329 citations

Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone.

1992 • 327 citations

Molecular biology of somatostatin receptors

1993 • 311 citations

Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor

1983 • 305 citations

Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant

1991 • 302 citations

Inherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6

1976 • 241 citations

Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone

1992 • 222 citations

Dramatic Pituitary Hyperplasia in Transgenic Mice Expressing a Human Growth Hormone-Releasing Factor Gene

1988 • 220 citations

Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues

1990 • 215 citations

Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone.

1993 • 180 citations

Etiology of Growth Hormone Deficiency in Little, Ames, and Snell Dwarf Mice^*

1983 • 155 citations

Genetic basis of endocrine disease. 6. Molecular basis of familial human growth hormone deficiency.

1994 • 147 citations

Desensitization studies using perifused rat pituitary cells show that growth hormone-releasing hormone and His-d-Trp-Ala-Trp-d-Phe-Lys-NH2 stimulate growth hormone release through distinct receptor sites

1991 • 146 citations

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor

1993 • 135 citations

Receptor-Associated Resistance to Growth Hormone-Releasing Factor in Dwarf "Little" Mice

1986 • 133 citations

Evolution of the growth hormone-releasing factor (GRF) family of peptides.

1992 • 123 citations

Binding sites for growth hormone releasing factor on rat anterior pituitary cells

1985 • 122 citations

Molecular Mechanism of Growth Hormone (GH) Deficiency in the Spontaneous Dwarf Rat: Detection of Abnormal Splicing of GH Messenger Ribonucleic Acid by the Polymerase Chain Reaction*

1990 • 104 citations

Mouse Growth Hormone-Releasing Hormone: Precursor Structure and Expression in Brain and Placenta

1989 • 95 citations

Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone

1993 • 94 citations

Expression of the growth hormone-releasing hormone gene and its peptide product in the rat ovary.

1992 • 92 citations

Genetic basis of endocrine disease. 6. Molecular basis of familial human growth hormone deficiency

1994 • 81 citations

Synthesis and expression of a gene for the rat glucagon receptor. Replacement of an aspartic acid in the extracellular domain prevents glucagon binding.

1994 • 77 citations

Growth Hormone Releasing Hormone

1986 • 68 citations

Growth hormone-releasing hormone is produced by rat Leydig cell in culture and acts as a positive regulator of Leydig cell function.

1992 • 65 citations

Expression and Localization of Growth Hormone-Releasing Hormone Messenger Ribonucleic Acid in Rat Placenta:In VitroSecretion and Regulation of its Peptide Product

1990 • 63 citations

Bovine adrenal glomerulosa and fasciculata cells exhibit 28.5-kilodalton proteins sensitive to angiotensin, other agonists, and atrial natriuretic peptide.

1993 • 63 citations

Structure and functional expression of a complementary DNA for porcine growth hormone-releasing hormone receptor

1993 • 62 citations

Expression of the growth hormone-releasing hormone gene and its peptide product in the rat ovary

1992 • 52 citations

Growth hormone-releasing factor stimulates adenylate cyclase activity in the anterior pituitary gland

1983 • 51 citations

Specific binding of synthetic human pancreatic growth hormone releasing factor (1–40-OH) to bovine anterior pituitaries

1985 • 45 citations

Assignment of the Human Growth Hormone-Releasing Hormone Receptor Gene (GHRHR) to 7p14 by in Situ Hybridization

1994 • 34 citations

A new target for growth hormone releasing-hormone action in rat: the Sertoli cell.

1993 • 31 citations

Growth hormone-releasing hormone is produced by rat Leydig cell in culture and acts as a positive regulator of Leydig cell function

1992 • 29 citations

Quantitative Aspects of Growth Hormone Cell Maturation in the Normal and Little Mutant Mouse

1988 • 25 citations

Photoaffinity cross-linking to the pituitary receptor for growth hormone-releasing factor.

1994 • 23 citations

Mouse Placental Cells Secrete Immunoreactive Growth Hormone-Releasing Factor1

1994 • 13 citations

Photoaffinity cross-linking to the pituitary receptor for growth hormone-releasing factor

1994 • 12 citations

The receptor revolution--multiplicity of G-protein-coupled receptors.

1993 • 12 citations

A new target for growth hormone releasing-hormone action in rat: the Sertoli cell

1993 • 11 citations