Cutting Edge: Alternative Signaling of Th17 Cell Development by Sphingosine 1-Phosphate

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

2005 • 3,961 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

Transforming growth factor-β induces development of the TH17 lineage

2006 • 3,014 citations

The two NF-κB activation pathways and their role in innate and adaptive immunity

2004 • 2,476 citations

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

2006 • 2,234 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

2006 • 1,403 citations

Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis

2006 • 1,043 citations

Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system

2006 • 947 citations

Interleukin-23 drives innate and T cell–mediated intestinal inflammation

2006 • 814 citations

Understanding the IL-23–IL-17 immune pathway

2005 • 759 citations

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

2005 • 681 citations

Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology

2006 • 664 citations

Interleukin-17 is a negative regulator of established allergic asthma

2006 • 561 citations

The immunosuppressant FTY720 down‐regulates sphingosine 1‐phosphate G protein‐coupled receptors

2004 • 532 citations

Antigen-Receptor Signaling to Nuclear Factor κB

2006 • 320 citations

Activation‐regulated expression and chemotactic function of sphingosine 1‐phosphate receptors in mouse splenic T cells

2002 • 229 citations

FTY720: ALTERED LYMPHOCYTE TRAFFIC RESULTS IN ALLOGRAFT PROTECTION

2001 • 175 citations

Type 4 sphingosine 1‐phosphate G protein‐coupled receptor (S1P₄) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration

2005 • 141 citations

IL-12– and IL-23–induced T helper cell subsets

2005 • 139 citations

Sphingolipids and the Balancing of Immune Cell Function: Lessons from the Mast Cell

2005 • 130 citations

Regulation of immunity by lysosphingolipids and their G protein–coupled receptors

2004 • 124 citations

Regulation of immunity by lysosphingolipids and their G protein–coupled receptors

2004 • 112 citations

Transduction of Multiple Effects of Sphingosine 1-Phosphate (S1P) on T Cell Functions by the S1P1 G Protein-Coupled Receptor

2003 • 99 citations

Cutting Edge: T Cell Requirement for CD28 Costimulation Is Due to Negative Regulation of TCR Signals by PTEN

2006 • 81 citations

Immunological Effects of Transgenic Constitutive Expression of the Type 1 Sphingosine 1-Phosphate Receptor by Mouse Lymphocytes

2005 • 64 citations

Comparative quantification of sphingolipids and analogs in biological samples by high-performance liquid chromatography after chloroform extraction

2006 • 43 citations

Th17 Augmentation in OTII TCR Plus T Cell-Selective Type 1 Sphingosine 1-Phosphate Receptor Double Transgenic Mice

2007 • 43 citations

Distinctive T Cell-suppressive Signals from Nuclearized Type 1 Sphingosine 1-Phosphate G Protein-coupled Receptors

2006 • 37 citations