High Rate of Recombination throughout the Human Immunodeficiency Virus Type 1 Genome

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

1995 • 1,139 citations

Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes

1993 • 788 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 637 citations

Retroviral Recombination and Reverse Transcription

1990 • 596 citations

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O

1998 • 564 citations

Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying Hypotheses

1979 • 529 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.

1990 • 477 citations

Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission

1996 • 447 citations

Recombination in AIDS viruses

1995 • 429 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 416 citations

The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin

1996 • 368 citations

Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity

1990 • 351 citations

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation.

1993 • 308 citations

Viral Quasispecies

1993 • 300 citations

Reverse Transcriptase and the Generation of Retroviral DNA

1997 • 271 citations

Human immunodeficiency virus 1 reverse transcriptase

1989 • 244 citations

Genetic Recombination

1987 • 200 citations

How Climate Evolved on the Terrestrial Planets

1988 • 195 citations

Slower evolution of human immunodeficiency virus type 1 quasispecies during progression to AIDS

1997 • 182 citations

Genetic recombination of human immunodeficiency virus

1989 • 180 citations

Viral quasi species.

1993 • 175 citations

Genetic variability of HIV-1

1996 • 153 citations

Human Immunodeficiency Virus Type 1 Intergroup (M/O) Recombination in Cameroon

1999 • 130 citations

Subtype G and Multiple Forms of A/G Intersubtype Recombinant Human Immunodeficiency Virus Type 1 in Nigeria

1999 • 125 citations

5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate

1992 • 120 citations

An Isolate of Human Immunodeficiency Virus Type 1 Originally Classified as Subtype I Represents a Complex Mosaic Comprising Three Different Group M Subtypes (A, G, and I)

1998 • 106 citations

Evolution and probable transmission of intersubtype recombinant human immunodeficiency virus type 1 in a Zambian couple

1997 • 106 citations

Evidence for a Unique Mechanism of Strand Transfer from the Transactivation Response Region of HIV-1

1997 • 106 citations

Retroviral DNA H structures: Displacement-assimilation model of recombination

1982 • 94 citations

High-frequency deletion between homologous sequences during retrotransposition of Ty elements in Saccharomyces cerevisiae.

1987 • 91 citations

The Nature of Human Immunodeficiency Virus Type 1 Strand Transfers

1998 • 87 citations

Development of a quasispecies of human immunodeficiency virus type 1 in vivo.

1992 • 87 citations

Sequence Note: Epidemic Expansion of HIV Type 1 Subtype C and Recombinant Genotypes in Tanzania

1998 • 86 citations

Human Immunodeficiency Virus Type 1 Quasispecies In Vivo and Ex Vivo

1992 • 81 citations

One retroviral RNA is sufficient for synthesis of viral DNA

1994 • 79 citations

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications

1995 • 78 citations

Inducible human immunodeficiency virus type 1 packaging cell lines

1996 • 76 citations

A Molecular Clone of HIV-1 Tropic and Cytopathic for Human and Chimpanzee Lymphocytes

1993 • 71 citations

Correlated Template-Switching Events during Minus-Strand DNA Synthesis: a Mechanism for High Negative Interference during Retroviral Recombination

1998 • 61 citations

Effect of gamma radiation on retroviral recombination

1992 • 55 citations

The Mechanism for Genetic Recombination in the Avian Retroviruses

1978 • 51 citations

The First Strand Transfer during HIV-1 Reverse Transcription Can Occur either Intramolecularly or Intermolecularly

1998 • 50 citations

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function

1997 • 50 citations

Dynamic changes in HIV‐1 quasispecies from azidothymidine (AZT)‐treated patients

1992 • 42 citations

Transmission of Human Immunodeficiency Type 1 Viruses with Intersubtype Recombinant Long Terminal Repeat Sequences

1999 • 37 citations

Intersubtype recombinant HIV-1 Sequences.

1997 • 32 citations

Updated proposal of reference sequences for the HIV-1 genetic subtypes.

1997 • 29 citations

Reverse transcription of the yeast ty1 retrotransposon: the mode of first strand transfer is either intermolecular or intramolecular 1 1Edited by M. Yaniv

1999 • 17 citations