Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

1995 • 1,139 citations

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

The Accuracy of Reverse Transcriptase from HIV-1

1988 • 982 citations

Fidelity of HIV-1 Reverse Transcriptase

1988 • 919 citations

DNA Replication Fidelity

2004 • 737 citations

Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus

1991 • 647 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Retroviral Recombination and Reverse Transcription

1990 • 596 citations

THE RETROVIRAL ENZYMES

1994 • 517 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

Selection, recombination, and G----A hypermutation of human immunodeficiency virus type 1 genomes

1991 • 339 citations

Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

1992 • 330 citations

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

1989 • 316 citations

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation.

1993 • 308 citations

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations.

1990 • 282 citations

New Procedure for DNA Transfection with Polycation and Dimethyl Sulfoxide

1984 • 217 citations

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.

1990 • 214 citations

Fidelity of HIV-1 reverse transcriptase copying RNA in vitro

1992 • 205 citations

Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro

1993 • 205 citations

GENERATION OF DIVERSITY IN RETROVIRUSES

1990 • 197 citations

Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro.

1989 • 189 citations

A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison

1991 • 186 citations

Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication

1988 • 157 citations

Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends.

1994 • 143 citations

Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer

1991 • 106 citations

Lower mutation rate of bovine leukemia virus relative to that of spleen necrosis virus

1994 • 103 citations

Determination of the mutation rate of a retrovirus

1988 • 87 citations

Comparison of Moloney murine leukemia virus mutation rate with the fidelity of its reverse transcriptase in vitro.

1992 • 68 citations

6 Roles of Ribonuclease H in Reverse Transcription

1993 • 63 citations

5 The Fidelity of Retroviral Reverse Transcriptases

1993 • 50 citations

Involvement of Directly Repeated Sequences in the Generation of Deletions of the Avian Sarcoma Virus src Gene

1983 • 49 citations

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector

1993 • 45 citations

Genetic Variation in Retroviruses

1990 • 44 citations

Truncated gag-related proteins are produced by large deletion mutants of Rous sarcoma virus and form virus particles

1985 • 39 citations

Direct determination of the point mutation rate of a murine retrovirus

1992 • 37 citations

Evolutionary variants of Rous sarcoma virus: large deletion mutants do not result from homologous recombination

1985 • 25 citations

Sequence divergence and open regions of RNA secondary structures in the envelope regions of the 17 human immunodeficiency virus isolates

1989 • 24 citations

7 Strand Displacement Synthesis by Reverse Transcriptase

1993 • 15 citations

Deleted Work

1955 • 0 citations