3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

World Cancer Report

2003 • 2,484 citations

Preferential Formation of Benzo[ a ]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

1996 • 1,636 citations

Sources of fine organic aerosol. 2. Noncatalyst and catalyst-equipped automobiles and heavy-duty diesel trucks

1993 • 1,441 citations

The IARC TP53 database: New online mutation analysis and recommendations to users

2002 • 1,248 citations

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.

2000 • 671 citations

Environment and Cancer: Who Are Susceptible?

1997 • 644 citations

NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

2000 • 604 citations

Inhaled particles and lung cancer. Part A: Mechanisms

2004 • 585 citations

Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.

2000 • 583 citations

Metabonomics in Toxicology: A Review

2005 • 537 citations

Mutagenicity and Carcinogenicity of Nitroarenes and Their Sources in the Environment

1986 • 473 citations

Aristolochic acid as a probable human cancer hazard in herbal remedies: a review

2002 • 471 citations

Mutagenicity of Nitroaromatic Compounds

2000 • 419 citations

DNA adducts : identification and biological significance

1994 • 401 citations

Oncogene Activation in Chemical Carcinogenesis

1988 • 383 citations

Expression and Regulation of Xenobiotic-Metabolizing Cytochrome P450 (CYP) Enzymes in Human Lung

2002 • 297 citations

Contribution of environmental factors to cancer risk

2003 • 291 citations

3-Nitrobenzanthrone, a Powerful Bacterial Mutagen and Suspected Human Carcinogen Found in Diesel Exhaust and Airborne Particulates

1997 • 275 citations

Atmospheric Reactions Influence Seasonal PAH and Nitro-PAH Concentrations in the Los Angeles Basin

2004 • 268 citations

The ‘A rule’ of mutagen specificity: A consequence of DNA polymerase bypass of non‐instructional lesions?

1991 • 260 citations

Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects

2001 • 251 citations

Lung Cancer in Railroad Workers Exposed to Diesel Exhaust

2004 • 221 citations

Carcinogen macromolecular adducts and their measurement

2000 • 215 citations

Sulfation of Thyroid Hormone and Dopamine during Human Development: Ontogeny of Phenol Sulfotransferases and Arylsulfatase in Liver, Lung, and Brain¹

2001 • 204 citations

Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues

1998 • 185 citations

³²P-Postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a]anthracene

1985 • 157 citations

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy

2004 • 144 citations

Sulfation of Thyroid Hormone and Dopamine during Human Development: Ontogeny of Phenol Sulfotransferases and Arylsulfatase in Liver, Lung, and Brain

2001 • 141 citations

Outdoor air pollution and lung cancer: Recent epidemiologic evidence

2004 • 138 citations

Environmental air pollution and DNA adducts in Copenhagen bus drivers—Effect of GSTM1 and NAT2 genotypes on adduct levels

1996 • 138 citations

Biomonitoring of polycyclic aromatic compounds in the urine of mining workers occupationally exposed to diesel exhaust

2002 • 134 citations

Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase

2002 • 132 citations

Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols

2005 • 123 citations

Xenobiotic metabolism enzyme gene expression in human bronchial epithelial and alveolar macrophage cells.

1996 • 104 citations

³²P-Postlabeung Methods for DNA Adduct Detection: Overview and Critical Evaluation

1994 • 98 citations

Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers

1995 • 96 citations

Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR

2001 • 96 citations

Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene

2004 • 95 citations

Surface Chemical Characterization of 2.5-μm Particulates (PM_2.5) from Air Pollution in Salt Lake City Using TOF-SIMS, XPS, and FTIR

2001 • 94 citations

Increase in mutation frequency in lung of Big Blue(R) rat by exposure to diesel exhaust

2000 • 90 citations

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

2003 • 84 citations

DNA adducts as markers of exposure to carcinogens and risk of cancer

2000 • 82 citations

In situ emission levels of carcinogenic and mutagenic compounds from diesel and gasoline engine vehicles on an expressway

1984 • 80 citations

DNA adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone

2005 • 77 citations

Activation of 3‐nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells

2003 • 75 citations

Identification of three major DNA adducts formed by the carcinogenic air pollutant 3‐nitrobenzanthrone in rat lung at the C8 and N² position of guanine and at the N⁶ position of adenine

2005 • 75 citations

DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by32P-postlabeling

2001 • 74 citations

Analysis of 13 32P-DNA Postlabeling Studies on Occupational Cohorts Exposed to Air Pollution

2001 • 73 citations

The presence of mutagens/carcinogens in the excised lung and analysis of lung cancer induction

1993 • 73 citations

32P-Postlabeling Analysis of DNA Adducts

2014 • 68 citations

p53 Mutations in Benzo(a)Pyrene-Exposed Human p53 Knock-in Murine Fibroblasts Correlate with p53 Mutations in Human Lung Tumors

2005 • 68 citations

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3‐nitrobenzanthrone in Muta Mouse

2004 • 66 citations

3-Aminobenzanthrone, a Human Metabolite of the Environmental Pollutant 3-Nitrobenzanthrone, Forms DNA Adducts after Metabolic Activation by Human and Rat Liver Microsomes: Evidence for Activation by Cytochrome P450 1A1 and P450 1A2

2004 • 66 citations

Sources of the atmospheric contaminants, 2-nitrobenzanthrone and 3-nitrobenzanthrone

2003 • 62 citations

The genotoxicity of 3-nitrobenzanthrone and the nitropyrene lactones in human lymphoblasts

2000 • 62 citations

Using polymerase arrest to detect DNA binding specificity of aristolochic acid in the mouse H-ras gene

2000 • 62 citations

3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells

2003 • 62 citations

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

2005 • 59 citations

DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats

2003 • 57 citations

Selected Nitro- and Nitro-oxy-polycyclic Aromatic Hydrocarbons

2003 • 56 citations

DNA adducts of carcinogenic aromatic amines.

1994 • 54 citations

UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.

2001 • 53 citations

An Unusual DNA Adduct Derived from the Powerfully Mutagenic Environmental Contaminant 3-Nitrobenzanthrone

1998 • 51 citations

DNA adduct formation from the mutagenic air pollutant 3-nitrobenzanthrone

1999 • 48 citations

Direct-acting mutagenicity of extracts of coal burning-derived particulates and contribution of nitropolycyclic aromatic hydrocarbons

2005 • 44 citations

Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells

2004 • 43 citations

Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods

2005 • 42 citations

Metabolism and DNA-Binding of 3-Nitrobenzanthrone in Primary Rat Alveolar Type II Cells, in Human Fetal Bronchial, Rat Epithelial and Mesenchymal Cell Lines

2000 • 42 citations

Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan

2003 • 42 citations

Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection

2003 • 40 citations

Synthesis and Characterization of Some Nitrobenzanthrones: Suspected New Mutagens in Atmospheric Environment

1997 • 37 citations

Determination of Atmospheric Nitrobenzanthrones by High-Performance Liquid Chromatography with Chemiluminescence Detection

2004 • 36 citations

Improvement in the diagnostic potential of ³²P-postlabeling analysis demonstrated by the selective formation and comparative analysis of nitrated-PAH-derived adducts arising from diesel particle extracts

1991 • 36 citations

The synthesis and application of fluorescent dyes based on 3-amino benzanthrone

2001 • 35 citations

Comparative dose-response study on the pulmonary carcinogenicity of 1, 6-dinitropyrene and benzo[a]pyrene in F344 rats

1989 • 34 citations

Seasonal and areal variations of polycyclic aromatic hydrocarbon concentrations in street dust determined by supercritical fluid extraction and gas chromatography–mass spectrometry

1995 • 33 citations

DNA adduct formation by the environmental contaminant 3‐nitrobenzanthrone after intratracheal instillation in rats

2005 • 32 citations

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes

2003 • 30 citations

Determination of benzanthrone in environmental samples

1995 • 30 citations

Occurrence and photostability of 3-nitrobenzanthrone associated with atmospheric particles

2002 • 30 citations

ABA-C₁₅: A New Dye for Probing Solvent Relaxation in Phospholipid Bilayers

2002 • 30 citations

Postlabelling analysis of DNA adducts formed in human hepatoma cells treated with 3-nitrobenzanthrone

2000 • 30 citations

Determination of the Mutagen 3-Nitrobenzanthrone in Rainwater Collected in Kyoto, Japan

2003 • 28 citations

DNA adducts of nitropolycyclic aromatic hydrocarbons.

1994 • 23 citations

in vivo metabolism and genotoxic effects of nitrated polycyclic aromatic hydrocarbons

1994 • 22 citations

Determination of mutagenic 3-nitrobenzanthrone in diesel exhaust particulate matter by three-dimensional high-performance liquid chromatography

2002 • 22 citations

Reaction of Benzanthrone (7H-Benz[d,e]anthracen-7-one) with Nitrogen Dioxide Alone or in Admixture with Ozone. Implications for the Atmospheric Formation of Genotoxic 3-Nitrobenzanthrone

1998 • 21 citations

Urothelial cell DNA adducts in rubber workers†

2002 • 21 citations

Dinitropyrenes induce gene mutations in multiple organs of the lambda/lacZ transgenic mouse (Muta™ Mouse)

2002 • 20 citations

A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes

2003 • 20 citations

Synthesis, Characterization, and ³²P-Postlabeling Analysis of DNA Adducts Derived from the Environmental Contaminant 3-Nitrobenzanthrone

2005 • 20 citations

Mutagenic Specificity of a Derivative of 3-Nitrobenzanthrone in the supF Shuttle Vector Plasmids

1998 • 20 citations

Orientation of pores in microporous polyethylene films as determined by polarized absorption spectroscopy

2001 • 11 citations

Colored microporous polyethylene films: effect of porous structure on dye adsorption

2002 • 8 citations

Luminescent studies of photoprotolytic reactions and competing nonradiative relaxation processes in dye solutions with two acid-base centers

1997 • 1 citations

Deleted Work

1955 • 0 citations