Environment and Cancer: Who Are Susceptible?

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

Preferential Formation of Benzo[ a ]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

1996 • 1,636 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

Migration Patterns and Breast Cancer Risk in Asian-American Women

1993 • 1,100 citations

Genetic Risk and Carcinogen Exposure: a Common Inherited Defect of the Carcinogen-Metabolism Gene Glutathione S-Transferase M1 (GSTM1) That Increases Susceptibility to Bladder Cancer

1993 • 709 citations

Differences in Lung Cancer Risk Between Men and Women: Examination of the Evidence

1996 • 707 citations

The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals

1995 • 657 citations

Breast Cancer and Serum Organochlorines: a Prospective Study Among White, Black, and Asian Women

1994 • 513 citations

Germ-LineBRCA1Mutations in Jewish and Non-Jewish Women with Early-Onset Breast Cancer

1996 • 394 citations

Misclassification of smoking status in the CARDIA study: a comparison of self-report with serum cotinine levels.

1992 • 376 citations

Cigarette Smoking, N-Acetyltransferase 2 Genetic Polymorphisms, and Breast Cancer Risk

1996 • 334 citations

Molecular Epidemiology: Insights Into Cancer Susceptibility, Risk Assessment, and Prevention

1996 • 304 citations

Reduced DNA repair capacity in lung cancer patients.

1996 • 299 citations

High Susceptibility to Lung Cancer Analyzed in Terms of Combined Genotypes of P450IA1 and Mu‐class Glutathione S‐Transferase Genes

1992 • 284 citations

Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens

1994 • 276 citations

Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients

1995 • 247 citations

Genetic variability of the human SRD5A2 gene: implications for prostate cancer risk.

1995 • 184 citations

Environmental Health Hazards: How Children Are Different from Adults

1995 • 179 citations

p53mutations in lung tumours: relationship to gender and lung DNA adduct levels

1996 • 174 citations

Acetylator Phenotype, Aminobiphenyl-Hemoglobin Adduct Levels, and Bladder Cancer Risk in White, Black, and Asian Men in Los Angeles, California

1994 • 171 citations

Contribution of genetic and nutritional factors to DNA damage in heavy smokers

1997 • 157 citations

The role of individual susceptibility in cancer burden related to environmental exposure.

1996 • 141 citations

The Genetic Basis of Cancer

1995 • 140 citations

Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer.

1996 • 139 citations

The Effect of Age at Smoking Initiation on Lung Cancer Risk

1993 • 132 citations

p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment.

1996 • 130 citations

Gender comparisons in human lung cancer: analysis of p53 mutations, anti-p53 serum antibodies and C-erbB-2 expression

1995 • 129 citations

COMMENTARY: Nature and nurture: possibilities for cancer control

1996 • 125 citations

From genes to public health: the applications of genetic technology in disease prevention. Genetics Working Group.

1996 • 121 citations

Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin

1991 • 110 citations

Polycyclic aromatic hydrocarbon–DNA adducts in smokers and their relationship to micronutrient levels and the glutathione-S-transferase M1 genotype

1994 • 93 citations

Children--unique and vulnerable. Environmental risks facing children and recommendations for response.

1995 • 86 citations

In vitro induction of benzo(a)pyrene diol epoxide-DNA adducts in peripheral lymphocytes as a susceptibility marker for human lung cancer.

1996 • 79 citations

Racial, ethnic, and gender variations in cancer risk: considerations for future epidemiologic research.

1995 • 44 citations

HRAS protooncogene polymorphism and breast cancer.

1993 • 39 citations

Mechanisms of carcinogenesis and individual susceptibility to cancer.

1994 • 37 citations

O⁶-Methylguanine-DNA Methyltransferase and uracil DNA glycosylase in human broncho-alveolar lavage cells and peripheral blood mononuclear cells from tobacco smokers and non-smokers

1991 • 37 citations

Human Interindividual Variability in Cancer Risks—Technical and Management Challenges

1996 • 37 citations

Mechanisms of carcinogenesis and individual susceptibility to cancer

1994 • 34 citations

Studying environmental influences and breast cancer risk: suggestions for an integrated population-based approach

1995 • 26 citations

Genetic predisposition to cancer

1991 • 19 citations

Topics in cancer risk assessment.

1997 • 12 citations

Application of molecular epidemiology to lung cancer chemoprevention

1996 • 8 citations

Hereditary cancer susceptibility

1996 • 6 citations