Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells

A simple technique for quantitation of low levels of DNA damage in individual cells

1988 • 10,537 citations

Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

2000 • 4,715 citations

The in vitro micronucleus technique

2000 • 2,456 citations

Mutagenicity and Carcinogenicity of Nitroarenes and Their Sources in the Environment

1986 • 473 citations

Mutagenicity of Nitroaromatic Compounds

2000 • 419 citations

3-Nitrobenzanthrone, a Powerful Bacterial Mutagen and Suspected Human Carcinogen Found in Diesel Exhaust and Airborne Particulates

1997 • 275 citations

A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing

1991 • 142 citations

Biomonitoring of polycyclic aromatic compounds in the urine of mining workers occupationally exposed to diesel exhaust

2002 • 134 citations

Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase

2002 • 132 citations

Heterocyclic aromatic amines induce DNA strand breaks and cell transformation

1999 • 102 citations

Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR

2001 • 96 citations

The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis (`comet') assay in metabolically-competent MCL-5 cells

1999 • 80 citations

Multimedia Analysis of PAHs and Nitro‐PAH Daughter Products in the Los Angeles Basin

2001 • 75 citations

The presence of mutagens/carcinogens in the excised lung and analysis of lung cancer induction

1993 • 73 citations

The genotoxicity of 3-nitrobenzanthrone and the nitropyrene lactones in human lymphoblasts

2000 • 62 citations

An Unusual DNA Adduct Derived from the Powerfully Mutagenic Environmental Contaminant 3-Nitrobenzanthrone

1998 • 51 citations

DNA adduct formation from the mutagenic air pollutant 3-nitrobenzanthrone

1999 • 48 citations

Human cell mutagenicity of mono- and dinitropyrenes in metabolically competent MCL-5 cells

1994 • 47 citations

Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes.

1999 • 43 citations

Metabolism and DNA-Binding of 3-Nitrobenzanthrone in Primary Rat Alveolar Type II Cells, in Human Fetal Bronchial, Rat Epithelial and Mesenchymal Cell Lines

2000 • 42 citations

Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan

2003 • 42 citations

Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.

1993 • 41 citations

Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection

2003 • 40 citations

Postlabelling analysis of DNA adducts formed in human hepatoma cells treated with 3-nitrobenzanthrone

2000 • 30 citations

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes

2003 • 30 citations

Occurrence and photostability of 3-nitrobenzanthrone associated with atmospheric particles

2002 • 30 citations

Determination of mutagenic 3-nitrobenzanthrone in diesel exhaust particulate matter by three-dimensional high-performance liquid chromatography

2002 • 22 citations

Mutagenicity of the atmospheric transformation products 2-nitrofluoranthene and 2-nitrodibenzopyranone in Salmonella and human cell forward mutation assays

1997 • 12 citations