Identification of three major DNA adducts formed by the carcinogenic air pollutant 3‐nitrobenzanthrone in rat lung at the C8 and N² position of guanine and at the N⁶ position of adenine

Enhanced sensitivity of 32P-postlabeling analysis of aromatic carcinogen:DNA adducts.

1985 • 476 citations

Mutagenicity of Nitroaromatic Compounds

2000 • 419 citations

DNA adducts : identification and biological significance

1994 • 401 citations

Contribution of environmental factors to cancer risk

2003 • 291 citations

3-Nitrobenzanthrone, a Powerful Bacterial Mutagen and Suspected Human Carcinogen Found in Diesel Exhaust and Airborne Particulates

1997 • 275 citations

Diesel and gasoline engine exhausts and some nitroarenes.

1989 • 259 citations

Lung Cancer in Railroad Workers Exposed to Diesel Exhaust

2004 • 221 citations

Carcinogen macromolecular adducts and their measurement

2000 • 215 citations

Outdoor air pollution and lung cancer: Recent epidemiologic evidence

2004 • 138 citations

Biomonitoring of polycyclic aromatic compounds in the urine of mining workers occupationally exposed to diesel exhaust

2002 • 134 citations

Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase

2002 • 132 citations

Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols

2005 • 123 citations

Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles

1994 • 116 citations

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

2003 • 84 citations

DNA adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone

2005 • 77 citations

Activation of 3‐nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells

2003 • 75 citations

DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by32P-postlabeling

2001 • 74 citations

3-Aminobenzanthrone, a Human Metabolite of the Environmental Pollutant 3-Nitrobenzanthrone, Forms DNA Adducts after Metabolic Activation by Human and Rat Liver Microsomes: Evidence for Activation by Cytochrome P450 1A1 and P450 1A2

2004 • 66 citations

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3‐nitrobenzanthrone in Muta Mouse

2004 • 66 citations

Sources of the atmospheric contaminants, 2-nitrobenzanthrone and 3-nitrobenzanthrone

2003 • 62 citations

3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells

2003 • 62 citations

The genotoxicity of 3-nitrobenzanthrone and the nitropyrene lactones in human lymphoblasts

2000 • 62 citations

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

2005 • 59 citations

DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats

2003 • 57 citations

DNA adducts of carcinogenic aromatic amines.

1994 • 54 citations

Facile aerial oxidation of the DNA-base adduct N-(2'-deoxyguanosin-8-yl)-2-aminofluorene [dG(C8)AF]

1990 • 52 citations

An Unusual DNA Adduct Derived from the Powerfully Mutagenic Environmental Contaminant 3-Nitrobenzanthrone

1998 • 51 citations

Formation of N‐(Deoxyguanosin‐8‐yl)aniline in the in vitro Reaction of N‐Acetoxyaniline with Deoxyguanosine and DNA

1989 • 50 citations

DNA adduct formation from the mutagenic air pollutant 3-nitrobenzanthrone

1999 • 48 citations

Direct-acting mutagenicity of extracts of coal burning-derived particulates and contribution of nitropolycyclic aromatic hydrocarbons

2005 • 44 citations

One-step conversions of a simple corrole into chiral and amphiphilic derivatives

2003 • 44 citations

Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells

2004 • 43 citations

Metabolism and DNA-Binding of 3-Nitrobenzanthrone in Primary Rat Alveolar Type II Cells, in Human Fetal Bronchial, Rat Epithelial and Mesenchymal Cell Lines

2000 • 42 citations

Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan

2003 • 42 citations

Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection

2003 • 40 citations

Improvement in the diagnostic potential of ³²P-postlabeling analysis demonstrated by the selective formation and comparative analysis of nitrated-PAH-derived adducts arising from diesel particle extracts

1991 • 36 citations

DNA adduct formation by the environmental contaminant 3‐nitrobenzanthrone after intratracheal instillation in rats

2005 • 32 citations

Tetrahedral intermediates formed by nitrogen and oxygen attack of aromatic hydroxylamines on acetyl cyanide

1987 • 31 citations

Occurrence and photostability of 3-nitrobenzanthrone associated with atmospheric particles

2002 • 30 citations

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes

2003 • 30 citations

Postlabelling analysis of DNA adducts formed in human hepatoma cells treated with 3-nitrobenzanthrone

2000 • 30 citations

Determination of the Mutagen 3-Nitrobenzanthrone in Rainwater Collected in Kyoto, Japan

2003 • 28 citations

DNA adducts of nitropolycyclic aromatic hydrocarbons.

1994 • 23 citations

Determination of mutagenic 3-nitrobenzanthrone in diesel exhaust particulate matter by three-dimensional high-performance liquid chromatography

2002 • 22 citations

Synthesis, Characterization, and ³²P-Postlabeling Analysis of DNA Adducts Derived from the Environmental Contaminant 3-Nitrobenzanthrone

2005 • 20 citations

A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes

2003 • 20 citations

Tetrahedral intermediates formed during acyl transfer. Reactions of acetyl cyanide

1985 • 17 citations