Interaction between two different regulatory elements activates the murine alpha A-crystallin gene promoter in explanted lens epithelia.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

A new method for sequencing DNA.

1977 • 7,941 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

The Lens: Development, Proteins, Metabolism and Cataract

1984 • 342 citations

Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus

1984 • 341 citations

Human HSP70 promoter contains at least two distinct regulatory domains.

1986 • 326 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322

1981 • 260 citations

Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron

1983 • 251 citations

Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

1985 • 242 citations

Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter

1986 • 239 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

Cell-specific expression of a transfected human α1-antitrypsin gene

1985 • 188 citations

Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.

1986 • 173 citations

Identification of a Transcriptional Enhancer Element Upstream from the Proto-Oncogene fos

1985 • 171 citations

Cell-specific enhancers in the rat exocrine pancreas.

1986 • 150 citations

An immunoglobulin promoter displays cell-type specificity independently of the enhancer

1985 • 144 citations

Lens crystallins and their gene families

1984 • 142 citations

Separate regulatory elements for the heat-inducible and ovarian expression of the drosophila hsp26 gene

1985 • 138 citations

Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia.

1985 • 132 citations

Orientation-Dependent Transcriptional Activator Upstream of a Human U2 snRNA Gene

1985 • 132 citations

Complete structure of the alpha B-crystallin gene: conservation of the exon-intron distribution in the two nonlinked alpha-crystallin genes.

1985 • 130 citations

Synergism between immunoglobulin enhancers and promoters

1986 • 116 citations

The yeast his3 promoter contains at least two distinct elements.

1982 • 102 citations

Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes.

1985 • 96 citations

Two Elements in the Bovine Leukemia Virus Long Terminal Repeat That Regulate Gene Expression

1986 • 94 citations

Structural and Evolutionary Relationships Among Five Members of the Human γ-Crystallin Gene Family

1985 • 90 citations

Concerted and divergent evolution within the rat γ-crystallin gene family

1986 • 85 citations

Contribution of Promoter to Tissue-Specific Expression of the Mouse Immunoglobulin Kappa Gene

1985 • 76 citations

Complete structure of the hamster αA crystallin gene

1985 • 75 citations

Lens-specific promoter activity of a mouse gamma-crystallin gene.

1985 • 67 citations

Analysis of the mouse γ-crystallin gene family: assignment of multiple cDNAs to discrete genomic sequences and characterization of a representative gene

1984 • 67 citations

Characterization of the human beta-crystallin gene Hu beta A3/A1 reveals ancestral relationships among the beta gamma-crystallin superfamily.

1986 • 63 citations

The appearance of α-crystallin in relation to cell cycle phase in the embryonic mouse lens

1983 • 54 citations

The role of enhancers in the regulation of cell-type-specific transcriptional control

1986 • 52 citations

Two human γ-crystallin genes are linked and riddled with Alu-repeats

1985 • 51 citations

Tissue-specific regulation of a chicken delta-crystallin gene in mouse cells: involvement of the 5′ end region.

1985 • 47 citations

Structural and functional evidence for differential promoter activity of the two linked delta-crystallin genes in the chicken.

1985 • 46 citations

DNA sequences responsible for tissue-specific expression of a chicken alpha-crystallin gene in mouse lens cells.

1985 • 45 citations

Alternative splicing of alpha A-crystallin RNA. Structural and quantitative analyses of the mRNAs for the alpha A2- and alpha Ains-crystallin polypeptides.

1984 • 43 citations

Gene expression and genetic engineering in the lens. Friedenwald lecture.

1987 • 41 citations

Intron insertions and deletions in the beta/gamma-crystallin gene family: the rat beta B1 gene.

1986 • 26 citations