The Lens: Development, Proteins, Metabolism and Cataract

Tissue sulfhydryl groups

1959 • 25,130 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

1973 • 7,616 citations

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

The period of susceptibility to the physiological effects of unilateral eye closure in kittens

1970 • 2,965 citations

Intermediate filaments as mechanical integrators of cellular space

1980 • 1,973 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975.

1980 • 1,269 citations

Coupled transport of sodium and organic solutes.

1970 • 1,175 citations

Manson's Tropical Diseases.

1973 • 980 citations

Glutathione: Metabolism and function

1978 • 971 citations

Theory of Transparency of the Eye

1971 • 876 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

1963 • 865 citations

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

1982 • 792 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 774 citations

THE FRAMINGHAM EYE STUDY

1977 • 772 citations

Nonenzymatic Browning in Vivo: Possible Process for Aging of Long-Lived Proteins

1981 • 754 citations

Mechanism for the several activities of the glutathione S-transferases.

1976 • 695 citations

Ammonia production in muscle and other tissues: the purine nucleotide cycle.

1972 • 681 citations

Lens Differentiation in Vertebrates

1981 • 638 citations

On the Enzymology of Amino Acid Transport

1973 • 637 citations

The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo.

1976 • 565 citations

Isolation and Properties of Lens Aldose Reductase

1965 • 561 citations

Ion Transport in Isolated Rabbit Ileum

1964 • 520 citations

Structure and Biosynthesis of Basement Membranes

1973 • 519 citations

High Blood Acetaldehyde Levels after Ethanol Administration

1975 • 514 citations

Hydrogen peroxide and human cataract

1981 • 497 citations

Origins of avian ocular and periocular tissues

1979 • 491 citations

Structural proteins of the mammalian lens: A review with emphasis on changes in development, aging and cataract

1976 • 482 citations

Isolation of γ-Glutamyl Transpeptidase from Hog Kidney

1965 • 459 citations

The Vertebrate Eye Lens

1977 • 449 citations

Molecular and Cellular Biology of the Eye Lens.

1981 • 447 citations

Nonhistone Chromosomal Proteins and Gene Regulation

1974 • 439 citations

The molecular structure and stability of the eye lens: X-ray analysis of γ-crystallin II

1981 • 432 citations

Formation of Polyols by the Lens of the Rat with ‘Sugar’ Cataract

1959 • 431 citations

Diabetic cataract formation: potential role of glycosylation of lens crystallins.

1978 • 411 citations

Pathogenic Mycoplasmas: Cultivation and Vertebrate Pathogenicity of a New Spiroplasma

1977 • 397 citations

Gangliosides as membrane receptors for tetanus toxin, cholera toxin and serotonin

1974 • 391 citations

Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes

1979 • 386 citations

Biogenesis and characterization of histone messenger RNA in HeLa cells

1972 • 383 citations

Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis

1960 • 382 citations

Isolation of three collagenous components of probable basement membrane origin from several tissues

1976 • 350 citations

Aspartic acid racemisation in the human lens during ageing and in cataract formation

1977 • 348 citations

Nonenzymatic Glucosylation of Low-Density Lipoprotein Alters Its Biologic Activity

1982 • 341 citations

Phospholipids in tissues of the eye I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids

1968 • 339 citations

Nonenzymatically glucosylated albumin. In vitro preparation and isolation from normal human serum.

1979 • 339 citations

Acetaldehyde adducts with hemoglobin.

1981 • 331 citations

The Amino‐Acid Sequence of the αA₂ Chain of Bovine α‐Crystallin

1973 • 304 citations

Molecular Aspects of Lens Cell Differentiation

1967 • 300 citations

Selective oxidation of cysteine and methionine in normal and senile cataractous lenses.

1980 • 299 citations

Characterization and Quantitative Determination of the Hydroxylysine-linked Carbohydrate Units of Several Collagens

1969 • 289 citations

Protides of the biological fluids

1973 • 289 citations

Free and protein-bound glutathione in normal and cataractous human lenses

1970 • 288 citations

Inductive Processes in Embryonic Development

1966 • 287 citations

The maturation of the lens cell: a morphologic study

1975 • 287 citations

Isolation of a collagen from basement membranes containing three identical α-chains

1971 • 287 citations

LEUCINE AMINOPEPTIDASE

1955 • 287 citations

Cataracts and Macular Degeneration in Older Americans

1982 • 278 citations

Hemoglobin Carbamylation in Uremia

1981 • 264 citations

Polyol Accumulation in Galactosemic and Diabetic Rats: Control by an Aldose Reductase Inhibitor

1973 • 262 citations

Oxidative changes in human lens proteins during senile nuclear cataract formation

1977 • 251 citations

Controlled Deamidation of Peptides and Proteins: An Experimental Hazard and a Possible Biological Timer

1970 • 245 citations

Lens Development: Fiber Elongation and Lens Orientation

1963 • 243 citations

Preface

1980 • 243 citations

Mechanisms of Cataract Formation in the Human Lens

1981 • 239 citations

Aldose reductase in diabetic complications of the eye

1979 • 237 citations

Studies on sodium-potassium-activated adenosinetriphosphatase. V. Correlation of enzyme activity with cation flux in six tissues

1963 • 235 citations

Ion analyses of human cataractous lenses

1975 • 234 citations

ORIENTED MICROTUBULES IN ELONGATING CELLS OF THE DEVELOPING LENS RUDIMENT AFTER INDUCTION

1964 • 225 citations

Prevalence and aetiology of cataract in Punjab.

1982 • 222 citations

The state of sulphydryl groups in normal and cataractous human lenses

1977 • 213 citations

DISPOSABLE SYRINGES

1974 • 212 citations

Cross-Linking of Lens Crystallins in a Photodynamic System: A Process Mediated by Singlet Oxygen

1980 • 204 citations

Regulation of hydrogen peroxide in eye humors effect of 3-amino-1H-1,2,4-triazole on catalase and glutathione peroxidase of rabbit eye

1977 • 201 citations

Differentiation of Lens Tissue from the Progeny of Chick Retinal Pigment Cells Cultured In Vitro : A Demonstration of a Switch of Cell Types in Clonal Cell Culture

1973 • 200 citations

Nonenzymatic glycosylation of erythrocyte membrane proteins. Relevance to diabetes.

1980 • 198 citations

Effect of flavone inhibitors of transport ATPases on histamine secretion from rat mast cells

1977 • 197 citations

CATARACT-THE ULTRAVIOLET RISK FACTOR

1981 • 196 citations

Identification of the cytoskeletal proteins in lens-forming cells, a special epithelioid cell type

1980 • 195 citations

Kinetics of Enzyme Mechanisms

1976 • 191 citations

Inhibition of lens aldose reductase by flavonoids—Their possible role in the prevention of diabetic cataracts

1976 • 190 citations

Diabetic Cataracts and Flavonoids

1977 • 189 citations

Senile Lens Changes and Diabetes in two Population Studies

1981 • 189 citations

GLUTATHIONE PEROXIDASE IN LENS AND A SOURCE OF HYDROGEN PEROXIDE IN AQUEOUS HUMOUR

1965 • 187 citations

Search for a biochemical basis of diabetic microangiopathy

1976 • 187 citations

SUNLIGHT AND CATARACT: AN EPIDEMIOLOGIC INVESTIGATION

1977 • 187 citations

Acetylation of protein N-terminal amino groups structural observations on α-amino acetylated proteins

1975 • 185 citations

Spectroscopic Evaluation and Classification of the Normal, Aging, and Cataractous Lens. (With 1 color plate)

1976 • 183 citations

Age-related changes in collagen: The identification of reducible lysine-carbohydrate condensation products

1972 • 182 citations

The Amino‐Acid Sequence of the αB₂ Chain of Bovine α‐Crystallin

1974 • 182 citations

Formation of N′-formylkynurenine in proteins from lens and other sources by exposure to sunlight

1971 • 181 citations

The Human Lens: In Relation to Cataract

1974 • 180 citations

Flavonoids as Inhibitors of Lens Aldose Reductase

1975 • 179 citations

Immunocytochemical localization of the lens main intrinsic polypeptide (MIP26) in communicating junctions.

1982 • 179 citations

The plasma membranes of eye lens fibres. Biochemical and structural characterization

1972 • 177 citations

Studies on the Oxidation of Cysteine to Cystine in Lens Proteins During Cataract Formation*

1951 • 177 citations

Nonenzymatic glycosylation of hemoglobin.

1977 • 176 citations

On the structural organization of isolated bovine lens fiber junctions.

1982 • 175 citations

Structural components of epithelial and endothelial basement membranes

1969 • 174 citations

Glutathione peroxidase activity in rat lens and other tissues in relation to dietary selenium intake

1974 • 174 citations

α-Crystallin. The isolation and characterization of distinct macromolecular fractions

1971 • 174 citations

Lens Protein

1982 • 169 citations

Fluorescent Glucoside in the Human Lens

1971 • 169 citations

Nonenzymatic glycosylation, sulfhydryl oxidation, and aggregation of lens proteins in experimental sugar cataracts.

1979 • 169 citations

Protein composition of bovine lens cortical fiber cell membranes

1975 • 168 citations

Intermolecular Cross-linking of Monomeric Proteins and Cross-linking of Oligomeric Proteins as a Probe of Quaternary Structure

1972 • 167 citations

Superoxide dismutase of the eye Relative functions of superoxide dismutase and catalase in protecting the ocular lens from oxidative damage

1978 • 167 citations

Effect of ethanol on glutathione concentration in isolated hepatocytes

1980 • 164 citations

Late complications of pterygium treatment.

1980 • 163 citations

On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses

1973 • 162 citations

AMMONIUM TOLERANCE IN LIVER DISEASE: OBSERVATIONS BASED ON CATHETERIZATION OF THE HEPATIC VEINS

1955 • 159 citations

Electrophoretic and immunoelectrophoretic studies on the soluble proteins in the developing lens of birds

1962 • 159 citations

Cyanate formation in solutions of urea

1971 • 159 citations

Immunofluorescent localization of collagen types I, II, and III in the embryonic chick eye

1977 • 159 citations

Leucine Aminopeptidase (Bovine Lens)

1973 • 159 citations

Ophthalmic Ultraviolet Action Spectra*

1956 • 157 citations

Disulfide-linked high molecular weight protein associated with human cataract.

1978 • 156 citations

Effect of 2450-Mhz Radiation on the Rabbit Eye

1975 • 154 citations

Isolation and Characterization of a Native Placental Basement‐Membrane Collagen and Its Component α Chains

1979 • 153 citations

Lens regeneration from the cornea in Xenopus laevis

1963 • 153 citations

Differentiation of Lens-Like Structures from Newt Iris Epithelial Cells In Vitro

1974 • 152 citations

The isomeric transformation of urea into ammonium cyanate in aqueous solutions

1948 • 152 citations

Studies on γ-crystallin from calf lens

1964 • 151 citations

Lens membranes II. Isolation and characterization of the main intrinsic polypeptide (MIP) of bovine lens fiber membranes

1976 • 151 citations

Osmotic changes in experimental galactose cataracts

1962 • 150 citations

The Control of Cell Division in the Ocular Lens

1971 • 147 citations

Studies on the Native and Reduced Alkylated Renal Glomerular Basement Membrane

1972 • 146 citations

Lens transglutaminase and cataract formation.

1981 • 145 citations

Studies on γ-crystallin from calf lens

1961 • 145 citations

L'aldose-réductase

1960 • 144 citations

Changes in human lens proteins during nuclear cataract formation

1977 • 143 citations

Studies on the Human Glomerular Basement Membrane: Composition, Nature of the Carbohydrate Units and Chemical Changes in Diabetes Mellitus

1973 • 142 citations

DNA degradation in terminally differentiating lens fiber cells from chick embryos.

1977 • 141 citations

Stepwise degradations and deamidation of the eye lens protein α-crystallin in ageing

1975 • 141 citations

EXPERIMENTAL STUDIES ON EARLY LENS CHANGES AFTER ROENTGEN IRRADIATION

1952 • 141 citations

Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts.

1978 • 139 citations

Eye Lens Color: Formation and Function

1971 • 139 citations

Inhibition of γ-Glutamylcysteine Synthetase by l-Methionine-S-sulfoximine

1973 • 138 citations

CP-45,634: A novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats

1979 • 137 citations

Identification of β carbolines isolated from fluorescent human lens proteins

1976 • 136 citations

Studies on an anophthalmic strain of mice I. Embryology of the eye region

1941 • 136 citations

Phospholipids in tissues of the eye. 3. Composition and metabolism of phospholipids in human lens in relation to age and cataract formation.

1969 • 134 citations

EXPERIMENTAL RADIATION CATARACTS

1951 • 134 citations

Lentropin: a factor in vitreous humor which promotes lens fiber cell differentiation.

1980 • 133 citations

Cataract and Abnormalities of the Lens

1975 • 133 citations

Biomolecular Structure, Conformation, Function, and Evolution

1981 • 132 citations

DEFICIENCY OF ERYTHROCYTE GALACTOKINASE IN A PATIENT WITH GALACTOSE DIABETES

1965 • 131 citations

Sorbitol pathway in diabetic and galactosemic rat lens

1974 • 130 citations

Cataract induced by administration of a single dose of sodium selenite to suckling rats

1978 • 129 citations

Primary Structure of the Bovine beta-Crystallin Bp Chain. Internal Duplication and Homology with gamma-Crystallin

1981 • 129 citations

The effect of diabetes on the content of sorbitol, glucose, fructose and inositol in the human lens

1964 • 129 citations

The metabolism of naphthalene and its toxic effect on the eye

1967 • 129 citations

The Quaternary Structure of Bovine alpha-Crystallin. Size and Charge Microheterogeneity: More than 1000 Different Hybrids?

1978 • 128 citations

Studies on sodium-potassium-activated adenosinetriphosphatase. VI. Its role in cation transport in the lens of cat, calf and rabbit

1963 • 127 citations

Differentiation of lens in cultures of neural retinal cells of chick embryos

1975 • 126 citations

Chapter 9: Cellular and Subcellular Events in Wolffian Lens Regeneration

1967 • 125 citations

Factors affecting the formation of sugar alcohols in ocular lens

1963 • 124 citations

Changes to the proteins of the human lens nucleus in cataract

1974 • 124 citations

Electron microscope observations on some structural proteins of the chick lens

1972 • 124 citations

Studies on the subunit composition of the renal glomerular basement membrane.

1976 • 124 citations

Does any enzyme follow the Michaelis—Menten equation?

1977 • 123 citations

The Quaternary Structure of Bovine α‐Crystallin

1980 • 122 citations

The yellow colour of the lens of man and other primates

1969 • 122 citations

The Biosynthesis of Basement Membrane Collagen in Embryonic Chick Lens

1972 • 121 citations

Morphological changes and growth stimulation of Bovine Epithelial Lens cells by a retinal extract in vitro

1978 • 121 citations

THE SAGITTAL GROWTH OF THE EYE

1971 • 120 citations

Nonenzymatic glycosylation of bovine lens crystallins. Effect of aging.

1981 • 119 citations

The amino acid sequence of γ-crystallin (fraction II) from calf lens

1972 • 119 citations

Metabolism of glutathione in the lens

1971 • 117 citations

Multiple Forms of Cytochrome c in the Rat

1968 • 116 citations

Role of nonenzymatic glycosylation in the development of the sequelae of diabetes mellitus

1979 • 116 citations

Spectroscopic investigations of bovine lens crystallins. 1. Circular dichroism and intrinsic fluorescence

1982 • 116 citations

Stem Cells and Tissue Homeostasis

1979 • 116 citations

Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activity

1982 • 113 citations

SELECTIVELY REDUCED HEPATIC ACETALDEHYDE DEHYDROGENASE IN ALCOHOLICS

1980 • 113 citations

Eye‐lens proteins: The three‐dimensional structure of β‐crystallin predicted from monomeric γ‐crystallin

1981 • 112 citations

DNA synthesis and mitotic activity during early development of chick lens

1968 • 111 citations

Photosensitization of the Eye with Methoxsalen

1961 • 111 citations

Structural basis for apparent heterogeneity of collagens in human basement membranes: type IV procollagen contains two distinct chains.

1980 • 111 citations

Cataract in Rats Fed on High Lactose Rations

1935 • 111 citations

The Lens Epithelium in the Pathogenesis of Cataract*

1957 • 111 citations

Lenticular intermediate-sized filaments: biosynthesis and interaction with plasma membrane.

1982 • 110 citations

The state of sulfhydryl groups in normal and cataractous human lens proteins. I. Nuclear region

1978 • 109 citations

The distribution and possible functions of ascorbic acid in the eye

1962 • 108 citations

LEUCINE AMINOPEPTIDASE

1957 • 107 citations

Sigmoid curves, non-linear double-reciprocal plots and allosterism

1975 • 107 citations

Deamidation In Vivo of an Asparagine Residue of Rabbit Muscle Aldolase

1972 • 107 citations

Aphakia, a New Mutation in the Mouse

1968 • 106 citations

Protein synthesis and ultrastructure during the formation of embryonic chick lens fibers in vivo and in vitro

1972 • 106 citations

Purification of rat liver RNase inhibitor and its effect on polyribosome integrity

1969 • 106 citations

Glutathione metabolism of the erythrocyte. The enzymic cleavage of glutathione–haemoglobin preparations by glutathione reductase

1970 • 105 citations

THE EXPRESSION OF DIFFERENTIATION BY CHICKEN LENS EPITHELIUM IN IN VITRO CELL CULTURE*

1971 • 105 citations

The relationship between morphogenetic cell death and the development of congenital anophthalmia

1974 • 105 citations

CELL ELONGATION IN THE CULTURED EMBRYONIC CHICK LENS EPITHELIUM WITH AND WITHOUT PROTEIN SYNTHESIS

1972 • 105 citations

Isolation and characterization of an age-dependent polypeptide from human lens with non-tryptophan fluorescence

1975 • 105 citations

EXPERIMENTAL STUDIES ON EARLY LENS CHANGES AFTER ROENTGEN IRRADIATION

1951 • 104 citations

Comparative analysis of the major polypeptides from liver gap junctions and lens fiber junctions.

1982 • 103 citations

Chapter 5 Problems of Differentiation in the Vertebrate Lens

1970 • 103 citations

Splitting and recombination of α-crystallin

1962 • 103 citations

Presbyopia and the water content of the human crystalline lens

1973 • 103 citations

Protein synthesis in the core of calf lens

1968 • 103 citations

Atom Bomb Cataracts

1949 • 103 citations

Regulation of protein synthesis, intracellular electrolytes and cataract formation in vitro

1977 • 103 citations

Glycosylation of hemoglobin in vitro: affinity labeling of hemoglobin by glucose-6-phosphate.

1976 • 102 citations

THE SOCALLED SENILE EXFOLIATION (PSEUDOEXFOLIATION) OF THE ANTERIOR LENS CAPSULE, A PRODUCT OF THE LENS EPITHELIUM. FIBRILLOPATHIA EPITHELIOCAPSULARIS

1964 • 102 citations

Studies on the structural proteins of the human lens

1969 • 101 citations

Differentiated Cell Types and the Regulation of Collagen Synthesis

1966 • 101 citations

A Comparative Study of Glycopeptides Derived from Selected Vertebrate Collagens

1970 • 101 citations

Carbamylation of lens proteins: A possible factor in cataractogenesis in some tropical countries

1980 • 101 citations

The effect of an aldose reductase inhibitor on the galactose-exposed rabbit lens

1968 • 101 citations

Cataracts in Patients Treated with Triparanol

1962 • 101 citations

[42] Crystalline leucine aminopeptidase from lens (α-aminoacyl-peptide hydrolase; EC 3.4.11.1)

1976 • 100 citations

Human lens cells have an in vitro proliferative capacity inversely proportional to the donor age

1979 • 100 citations

Conformational changes in human lens proteins in cataract

1972 • 99 citations

Translation of Two Messenger RNAs from Lens in a Cell Free System from Krebs II Ascites Cells

1972 • 99 citations

Selected Topics in Ophthalmic Biochemistry

1964 • 97 citations

Terminal lens cell differentiation I. Histological and microspectrophotometric analysis of nuclear Degeneration

1970 • 97 citations

Differentiation of lens fibers in explanted embryonic chick lens epithelia

1973 • 97 citations

Oral Toxicity of Mirex in Adult and Suckling Rats

1970 • 97 citations

Glycosylated collagen

1979 • 96 citations

Calmodulin Binds to Chick Lens Gap Junction Protein in a Calcium-Independent Manner

1982 • 95 citations

DNA synthesis and the incorporation of labeled iris cells into the lens during lens regeneration in adult newts

1971 • 95 citations

Le mécanisme de la formation du fructose séminal et du fructose foetal

1960 • 95 citations

Lens membranes IV. Preparative isolation and characterization of membranes and various membrane proteins from calf lens

1978 • 95 citations

The Biosynthesis of Basement Membrane Collagen in Embryonic Chick Lens

1973 • 95 citations

Aetiology of climatic droplet keratopathy and pterygium.

1980 • 95 citations

The absence of cataracts in mice with congenital hyperglycemia

1974 • 95 citations

Incidence of Ocular Complications in Patients Undergoing Renal Transplantation

1972 • 95 citations

Lens Epithelial Cell Elongation in the Absence of Microtubules: Evidence for a New Effect of Colchicine

1979 • 93 citations

The interrelationship between monomeric, oligomeric and polymeric α-crystallin in the calf lens nucleus

1979 • 92 citations

Disulphide cross-linked protein of high molecular weight in human cataractous lens

1973 • 92 citations

The human lens

1972 • 92 citations

Leucine Aminopeptidase (Bovine Lens)

1971 • 91 citations

The concentration and localization of heavy molecular weight aggregates in aging normal and cataractous human lenses

1975 • 91 citations

Protection against Superoxide Radicals in Rat Lens

1977 • 90 citations

The Lens Capsule

1969 • 90 citations

Evidence For Nonthermal Effects of Microwave Radiation: Abnormal Development of Irradiated Insect Pupae

1971 • 90 citations

Biological Effects of Microwave Radiation

1971 • 90 citations

THE EFFECT OF INSULIN ON THE UPTAKE OF MONOSACCHARIDES BY THE RAT LENS

1961 • 89 citations

Non-tryptophan fluorescence associated with human lens protein; Apparent complexity and isolation of bityrosine and anthranilic acid

1978 • 89 citations

Purification and composition studies of βs-crystallin

1966 • 89 citations

Philly mouse: A new model of hereditary cataract

1980 • 89 citations

Mechanism of cataract production by 3-β(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride, U18666A: An inhibitor of cholesterol biosynthesis

1979 • 88 citations

The Biosynthesis of Basement Membrane Collagen in Embryonic Chick Lens

1972 • 88 citations

Reducible components in the proteins of human erythrocyte membrane

1976 • 88 citations

A Study of the C14-Glucose Metabolism of the Rabbit Lens

1958 • 87 citations

Anticholinesterase Drugs and Cataracts

1966 • 87 citations

Fractionation of Glycoprotein Components of the Reduced Alkylated Renal Glomerular Basement Membrane

1972 • 87 citations

The Ocular Toxic Findings With Prolonged and High Dosage Chlorpromazine Intake

1965 • 86 citations

Electron microscopic observations of the developing mouse eye

1961 • 86 citations

Elemental analysis in normal and cataractous human lens tissue

1971 • 86 citations

A comprehensive examination of protein sequences for evidence of internal gene duplication

1978 • 86 citations

Isolation and protein pattern of eye lens fiber junctions

1974 • 86 citations

The cytoskeleton of chick lens cells

1979 • 85 citations

Isolation and identification of stimulatory and inhibitory cell growth factors in bovine vitreous

1982 • 85 citations

Morphology of hereditary mouse cataract

1974 • 85 citations

GROWTH OF LENS AND OCULAR ENVIRONMENT: ROLE OF NEURAL RETINA IN THE GROWTH OF MOUSE LENS AS REVEALED BY AN IMPLANTATION EXPERIMENT

1976 • 84 citations

Composition of ox lens capsule

1951 • 84 citations

The behaviour of reduced proteins from normal and cataractous lenses in highly dissociating media: Cross-linked protein in cataractous lenses

1972 • 84 citations

IDENTIFICATION OF THE SCATTERING ELEMENTS RESPONSIBLE FOR LENS OPACIFICATION IN COLD CATARACTS

1982 • 84 citations

Posterior subcapsular cataracts and glaucoma associated with long-term oral corticosteroid therapy. In patients with rheumatoid arthritis and related conditions.

1969 • 84 citations

The development of the kitten's visual optics

1976 • 83 citations

Properties of the nicotinamide adenine dinucleotide phosphate-dependent aldehyde reductase from pig kidney. Amino acid composition, reactivity of cysteinyl residues, and stereochemistry of D-glyceraldehyde reduction.

1975 • 83 citations

Cortical opacity, calcium concentration and fiber membrane structure in the calf lens

1980 • 83 citations

THE FREQUENCY OF CATARACT AFTER MIOTIC THERAPY

1966 • 83 citations

The postnatal growth of the capsule of the human crystalline lens.

1972 • 83 citations

Isolation of polymerization‐competent vimentin from porcine eye lens tissue

1981 • 83 citations

Lens antigens in a lens-regenerating system studied by the immunofluorescent technique

1964 • 82 citations

Galactitol in the Tissues of a Galactosemic Child

1966 • 82 citations

Molecular weight and subunit structure of delta-crystallin from embryonic chick lens fibers

1974 • 82 citations

Primary Gene Products of Bovine β‐Crystallin and Reassociation Behavior of Its Aggregates

1982 • 82 citations

Structural aspects of bovine β-crystallins: Physical characterization including dissociation-association behavior

1981 • 82 citations

Cataract and Diabetes

1964 • 82 citations

Cortical cataract formation prevented by vitamin E and glutathione

1979 • 81 citations

Intracellular Degradation and Deamidation of α‐Crystallin Subunits

1976 • 81 citations

Human lens membrane: Comparison of major intrinsic polypeptides from young and old lenses isolated by a new methodology

1979 • 81 citations

Differentiation of rat lens epithelial cells in tissue culture

1977 • 81 citations

The sorbitol pathway in the lens

1962 • 81 citations

The elastic constants and ultrastructural organization of a basement membrane (lens capsule)

1976 • 81 citations

Racemization in human lens: evidence of rapid insolubilization of specific polypeptides in cataract formation.

1978 • 80 citations

Control of Tissue Specificity: The Pattern of Cellular Synthetic Activities in Tissue Transformation

1966 • 80 citations

Insulin initiation of lens fiber differentiation in culture: Elongation of embryonic lens epithelial cells

1973 • 80 citations

Factors affecting the cation transport of calf lens

1961 • 80 citations

Effect of Insulin on Pathways of Glucose Oxidation in the Rat Lens

1961 • 80 citations

Acute Microwave Irradiation and Cataract Formation in Rabbits and Monkeys^*

1978 • 79 citations

Changes in lens during the formation of X-ray cataract in rabbits. 2

1954 • 79 citations

Cataract Induction in Mice Exposed to Near UV Light

1974 • 79 citations

The Quaternary Structure of Bovine alpha-Crystallin. Size and Shape Studies by Sedimentation, Small-angle X-Ray Scattering and Quasi-elastic Light Scattering

1978 • 79 citations

Actin in Mammalian Lens

1979 • 79 citations

Transformation of Iris into Lens in vitro and its Dependency on Neural Retina

1973 • 78 citations

Glucosylation of human lens protein and cataractogenesis

1979 • 78 citations

Some properties of lens plasma membrane polypeptides isolated from normal human lenses

1979 • 78 citations

SELECTIVE LIGHT ABSORPTION BY THE LENSES OF LOWER VERTEBRATES, AND ITS INFLUENCE ON SPECTRAL SENSITIVITY

1956 • 78 citations

Changes in the lens related to the reduction of transparency

1973 • 77 citations

Terminal lens cell differentiation

1969 • 77 citations

Microtubules in the Lens

1968 • 77 citations

Phospholipids in tissues of the eye

1969 • 77 citations

Photosensitization of the Eye with Methoxsalen

1960 • 76 citations

Studies on β-crystallin I. Isolation and partial characterization of the principal polypeptide chain

1974 • 76 citations

The mechanism of the glyoxalase I reaction, and the effect of ophthalmic acid as an inhibitor

1961 • 76 citations

The retention of differentiated properties by lens epithelial cells in clonal cell culture

1973 • 76 citations

Osmotic Effects on the Amino Acid-concentrating Mechanism in the Rabbit Lens

1965 • 76 citations

Physical and kinetic properties of homogenous bovine lens aldose reductase.

1976 • 76 citations

Metabolism of xylose by the lens. 2. Rat lens in vivo and in vitro

1959 • 76 citations

The Lens Capsule

1969 • 76 citations

Leucinaminopeptidase aus Rinderaugenlinsen. Kristallisation, Eigenschaften und optimale Wirkungsbedingungen des Enzyms

1965 • 75 citations

Short-and Long-Lived Messenger RNA in Embryonic Chick Lens

1965 • 75 citations

Receptors for insulin and epidermal growth factor: Relation to synthesis of DNA in cultured rabbit lens epithelium

1975 • 75 citations

Biochemical changes associated with the development and reversal of galactose cataracts

1976 • 75 citations

PURIFICATION AND PROPERTIES OF BRAIN ALDOSE REDUCTASE AND <scp>l</scp>‐HEXONATE DEHYDROGENASE*

1967 • 75 citations

Leucine aminopeptidase (bovine lens). The relative binding of cobalt and zinc to leucine aminopeptidase and the effect of cobalt substitution on specific activity.

1976 • 74 citations

Studies on the assembly of the rat lens capsule. Biosynthesis and partial characterization of the collagenous components

1978 • 74 citations

Pseudoexfoliative disease of the lens: a study in electron microscopy and histochemistry.

1977 • 74 citations

Gamma crystallins in Wolffian lens regeneration demonstrated by immunofluorescence

1966 • 74 citations

Ocular protein alterations by near UV light

1973 • 74 citations

Lens membranes 1. Composition of urea-treated plasma membranes from calf lens

1974 • 74 citations

Biochemistry of cell differentiation II

1977 • 73 citations

The isolation, and amino acid and carbohydrate composition, of polymeric collagens prepared from various human tissues

1971 • 73 citations

Loss during development of the ability of chick embryonic lens cells to elongate in culture: Inverse relationship between cell division and elongation

1972 • 73 citations

Differences in the susceptibility of various aldose reductases to inhibition. II.

1980 • 73 citations

Activation of ribosomal RNA synthesis in initiation of Wolffian lens regeneration

1969 • 73 citations

Biochemical and immunological studies of lentoid formation in cultures of embryonic chick neural retina and day-old chick lens epithelium

1977 • 73 citations

Collagen heterogeneity in the avian eye: Lens, vitreous body, cornea and sclera

1974 • 73 citations

Age-related changes in the structural proteins of human lens

1972 • 72 citations

Cytoplasmic filaments in the crystalline lens of various species: Functional correlations

1978 • 72 citations

Classification of human senile cataracts by nuclear colour and sodium content

1980 • 71 citations

The distribution of the soluble proteins in the calf lens

1973 • 71 citations

Structural Characterization of a Soluble Fraction from Lens‐Capsule Basement Membrane

1973 • 71 citations

Relationship of aardvark to elephants, hyraxes and sea cows from α-crystallin sequences

1981 • 71 citations

An Extrinsic Membrane Polypeptide Associated with High-Molecular-Weight Protein Aggregates in Human Cataract

1979 • 71 citations

Cyclotron-induced Radiation Cataracts

1949 • 71 citations

Coloration of human lenses by near ultraviolet photo-oxidized tryptophan

1972 • 71 citations

Regulation of Glucose-6-Phosphate Dehydrogenase Activity in Red Blood Cells From Hemolytic and Nonhemolytic Variant Subjects

1973 • 71 citations

Aldose reductase activity in the lens and other tissues

1966 • 70 citations

Cholesterol and phospholipids in protein fractions of human lens and senile cataract

1978 • 70 citations

The Quaternary Structure of Bovine α‐Crystallin

1979 • 70 citations

Relationship between Age and Properties of Human and Rabbit Erythrocyte Glucose‐6‐Phosphate Dehydrogenase

1969 • 70 citations

Stimulation of lens regeneration from the newt dorsal iris when implanted into the blastema of the regenerating limb

1973 • 70 citations

Cytoskeletal and contractile structures in bovine lens cell differentiation

1981 • 70 citations

The amino acid sequence of the A chain of human α‐crystallin

1975 • 69 citations

Lens-specific antigens and cytodifferentiation in the developing lens

1968 • 69 citations

Evidence for a “non-genetic” origin of the A1 chains of α-crystallin

1972 • 69 citations

Stimulation of the hexose monophosphate shunt in rabbit lens in response to the oxidation of glutathione

1981 • 69 citations

Biochemistry of bovine lens proteins I. Isolation and characterization of adult α-crystallins

1962 • 69 citations

Identification and quantification of leucine aminopeptidase in aged normal and cataractous human lenses and ability of bovine lens LAP to cleave bovine crystallins

1982 • 69 citations

Photo-oxidation of lens proteins by sunlight in the presence of fluorescent derivatives of kynurenine, isolated from the human lens

1973 • 68 citations

Isolation and characterization of cyanogen bromide peptides from basement membrane collagen

1972 • 68 citations

Raman spectroscopic measurement of total sulfhydryl in intact lens as affected by aging and ultraviolet irradiation. Deuterium exchange as a probe for accessible sulfhydryl in living tissue.

1978 • 68 citations

Total sulfhydryl by Raman spectroscopy in the intact lens of several species: Variations in the nucleus and along the optical axis during aging

1982 • 68 citations

Calcium content and distribution in human cataract

1982 • 68 citations

Glutathione reductase in normal and cataractous human lenses

1978 • 68 citations

Changes in lens during the formation of X-ray cataract in rabbits

1953 • 68 citations

Cataract and Other Ocular Changes Resulting from Tryptophane Deficiency

1942 • 68 citations

Role of nonenzymatic glycosylation in experimental cataract formation

1980 • 68 citations

Quantitation of delta-crystallin messenger RNA during lens induction in chick embryos.

1976 • 67 citations

Subunits of Alpha-Crystallin from Adult and Embryonic Cattle Lens

1968 • 67 citations

Physicochemical characterization of lens proteins of the squid nototodarus gouldi and comparison with vertebrate crystallins

1982 • 67 citations

Microtubules and microfilaments of bovine lens epithelial cells: Electron microscopy and immunofluorescence staining with specific antibodies

1976 • 67 citations

A change in the stoichiometry of assembly of bovine lens α-crystallin subunits in relation to cellular differentiation

1974 • 67 citations

Rat alpha-Crystallin A Chain with an Insertion of 22 Residues

1978 • 67 citations

Collagen crosslinks: Occurrence in basement membrane collagens

1973 • 66 citations

Cataract and Anomalies of the Lens

1945 • 66 citations

An experimental study of the role of optic cup and overlying ectoderm in lens formation in the chick embryo

1937 • 66 citations

Pyridine nucleotides in ocular tissues as determined by the cycling assay

1980 • 66 citations

Immunofluorescence localization of the crystallins in amphibian lens development, with special reference to the γ-crystallins

1969 • 66 citations

A Model for the Architecture of α-Crystallin

1979 • 66 citations

Isolation and characterization of two collagenous components from anterior lens capsule

1978 • 66 citations

Biochemical and fine structure studies on the water-insoluble components of the calf lens

1972 • 66 citations

Swelling of the lens fibers

1975 • 66 citations

Some properties of the low molecular weight α-crystallin from normal human lens: Comparison with bovine lens

1976 • 66 citations

Fluorescence of N'-formylkynurenine and of protein exposed to sunlight

1972 • 66 citations

Possible reactions of 1,2-naphthaquinone in the eye.

1967 • 66 citations

The production of superoxide radicals in reactions of the herbicide diquat

1971 • 65 citations

Über Darmerepsin. Mit 9 Figuren im Text.

1929 • 65 citations

Stabilization of mRNA templates in bovine lens epithelial cells

1967 • 65 citations

δ-Crystallin mRNA in chick lens cells: mRNA accumulates during differential stimulation of δ-crystallin synthesis in cultured cells

1976 • 65 citations

LENS CELL ELONGATION IN VITRO AND MICROTUBULES

1975 • 65 citations

Is actin in eye lens a possible factor in visual accommodation?

1980 • 65 citations

Intracellular Degradation of alpha-Crystallin. Fractionation and Characterization of Degraded alphaA-Chains

1974 • 64 citations

Changes in Lens Proteins of Rats During Aging

1956 • 64 citations

The pattern of DNA synthesis in the lens epithelium and the annular pad during development and growth of the chick lens

1970 • 64 citations

The Unusual Links and Cross-Links of Collagen

1965 • 64 citations

Galactokinase Deficiency as a Cause of Cataracts

1973 • 64 citations

Lens Opacities in Glaucoma Patients on Phospholine Iodide Therapy

1966 • 64 citations

The distribution of reducing substances between the intra‐ocular fluids and blood plasma, and the kinetics of penetration of various sugars into these fluids

1948 • 64 citations

A Light-catalysed Reaction in the Aqueous Humour of the Eye

1965 • 64 citations

Control of lens glycolysis

1967 • 63 citations

Rates of protein synthesis in explanted embryonic chick lens epithelia: Differential stimulation of δ-crystallin synthesis

1975 • 63 citations

Changes in the distribution of proteins in the aging human lens

1977 • 63 citations

Messenger RNA Utilization during Development of Chick Embryo Lens

1965 • 62 citations

Handbook of Protein Sequence Analysis

1981 • 62 citations

Purification and Immunologic Identification of Aldose Reductases

1974 • 62 citations

Development of optical quality in the kitten eye

1978 • 62 citations

NEAR UV LIGHT AND CATARACTS*

1977 • 62 citations

Isolation and In Vitro Translation of δ-Crystallin mRNA from Embryonic Chick Lens Fibers

1974 • 62 citations

The state of water in normal and senile cataractous lenses studied by nuclear magnetic resonance

1979 • 62 citations

Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues.

1979 • 62 citations

Characterization of basement membrane collagen of bovine anterior lens capsule via segment‐long‐spacing crystallites and the specific cleavage of the collagen by pepsin

1978 • 62 citations

Characterization of chick lens soluble proteins and the control of their synthesis

1978 • 62 citations

Studies on an anophthalmic strain of mice

1978 • 62 citations

Cataracts and abnormal proliferation of the lens epithelium in mice carrying the CatFr gene

1969 • 62 citations

Distribution of aldose reductase in ocular tissues

1981 • 61 citations

A study of the fine structure of the optic vesicle and lens placode of the chick embryo during induction

1961 • 61 citations

Intracellular Carboxy‐Terminal Degradation of the αA Chain of α‐Crystallin

1974 • 61 citations

Biochemical changes associated with selenite-induced cataract in the rat

1981 • 61 citations

Human insoluble lens protein II. Isolation and characterization of a 9600 dalton polypeptide

1978 • 61 citations

Reduction of glutathione coupled with oxidative decarboxylation of malate in cattle lens

1953 • 61 citations

Ontogeny and localization of the crystallins during embryonic lens development in Xenopus laevis

1973 • 61 citations

The Subunit Structure of α‐Crystallin

1969 • 61 citations

Nonenzymatic Glycosylation and Browning in Diabetes and Aging: Studies on Lens Proteins

1982 • 61 citations

The Experimental Production of Cataracts by Exposure to Heat and Light

1960 • 61 citations

Anterior polar and posterior subcapsular cataract in a patient with retinitis pigmentosa: a light-microscopic and ultrastructural study

1976 • 60 citations

Molecular cloning and partial characterization of delta-crystallin cDNA sequences in a bacterial plasmid.

1979 • 60 citations

Improved resolution of calf lens β-crystallins

1979 • 60 citations

Lenticular Changes in Microwave Workers

1966 • 60 citations

Cataract produced by tyrosinase and tyrosine systems in rabbit lens in vitro

1969 • 60 citations

Human β-crystallin

1980 • 60 citations

Further studies on the polypeptide chains of β-crystallin

1975 • 60 citations

Gamma-crystallin, a major cytoplasmic polypeptide disulfide linked to membrane proteins in human cataract

1981 • 60 citations

Crystallin synthesis by Chick Lens

1971 • 60 citations

Cytological study of philly mouse cataract

1980 • 60 citations

Structural studies on calf lens γ-crystallin fraction IV: A comparison of the cysteine-containing tryptic peptides with the corresponding amino acid sequence of γ-crystallin fraction II

1978 • 59 citations

Role of glycosylation in protein disulfide formation and cataractogenesis

1980 • 59 citations

Enhancement of differentiation of lens and pigment cells by ascorbic acid in cultures of neural retinal cells of chick embryos

1976 • 59 citations

Population Character and Variety in Subunit Structure of High‐Molecular‐Weight Proteins from the Bovine Eye Lens

1973 • 59 citations

Studies on the Glutathione in Bovine Lens

1957 • 59 citations

Chicken lens crystallin DNA sequences show at least two δ-crystallin genes

1980 • 59 citations

An electron-microscope study of adult mouse lens: Some ultrastructural specializations

1974 • 59 citations

Biochemical evidence for membrane disintegration in human cataracts.

1981 • 59 citations

Protein changes in the human lens during development of sentile nuclear cataract

1976 • 58 citations

Resolution of two distinct embryonic chick δ-crystallin bands by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate and urea

1977 • 58 citations

Conversion of glutathione to glutathione disulfide, a catalytic function of gamma-glutamyl transpeptidase.

1979 • 58 citations

Reversibility of Corticosteroid-Associated Cataracts in Children with the Nephrotic Syndrome

1977 • 58 citations

Acute reversible lens opacity: Caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration

1970 • 58 citations

Roentgen-Ray Cataract

1936 • 58 citations

Cataracts as an Epidemiologic Problem

1977 • 58 citations

Effects of Small Daily Doses of Fast Neutrons on Mice

1948 • 58 citations

Cataract Incidence in Radar Workers

1965 • 58 citations

IN VITRO ANALYSES OF WOLFFIAN LENS REGENERATION: DIFFERENTIATION OF THE REGENERATING LENS RUDIMENT OF THE NEWT, TRITURUS PYRRHOGASTER¹⁾²⁾

1967 • 58 citations

The binding of thyrotropin to liposomes containing gangliosides

1977 • 58 citations

Calf Crystallin Synthesis in Frog Cells: The Translation of Lens-Cell 14S RNA in Oocytes

1972 • 58 citations

Cultured calf lens epithelium. I. Methods of cultivation and characteristics of the cultures

1974 • 57 citations

The nature and origin of the urea-insoluble protein of human lens

1972 • 57 citations

What Happens to the Human Lens in Cataract

1975 • 57 citations

Myotonia induced by diazacholesterol: Increased (Na+ + K+)-ATPase activity of erythrocyte ghosts and development of cataracts

1973 • 57 citations

Enzymes of mercapturate synthesis and other drug-metabolizing reactions-specific localization in the eye

1981 • 57 citations

Lens membranes VII. MIP is an immunologically specific component of lens fiber membranes and is identical with 26K band protein

1979 • 57 citations

Circular dichroism and optical rotatory dispersion of the aggregates of purified polypeptides of alpha-crystallin

1974 • 57 citations

Anterior lens capsule collagens: cyanogen bromide peptides of the C chain

1979 • 57 citations

The rôle of calcium in senile cataract

1929 • 57 citations

Tryptophan Excited States and Cataracts in the Human Lens

1973 • 57 citations

Differential metabolism and leakage of protein in an inherited cataract and a normal lens cultured with ouabain

1978 • 57 citations

Aspects of mitotic activity in relation to cell proliferation in the lens epithelium

1962 • 56 citations

Cataracts, galactosuria and hypergalactosemia due to galactokinase deficiency in a child

1971 • 56 citations

Developmental changes in the low molecular weight proteins of the bovine lens

1973 • 56 citations

Presenile Cataract Formation and Decreased Activity of Galactosemic Enzymes

1980 • 56 citations

A possible cataractogenic factor in the Nakano mouse lens

1978 • 56 citations

Human Ultraviolet Radiation Cataracts (With 1 color plate)

1980 • 56 citations

Kinetics and mechanism of action of aldehyde reductase from pig kidney

1979 • 56 citations

The State of Aggregation of α‐Crystallin Detected after Large‐Scale Preparation by Zonal Centrifugation

1972 • 56 citations

Relationship between crystallin mRNA expression in retina cells and their capacity to re-differentiate into lens cells

1979 • 56 citations

THE OCULAR EFFECTS OF MICROWAVES ON HYPOTHERMIC RABBITS: A STUDY OF MICROWAVE CATARACTOGENIC MECHANISMS*

1975 • 56 citations

Polyol-pathway enzymes of human brain. Partial purification and properties of aldose reductase and hexonate dehydrogenase

1980 • 55 citations

The metabolism of glucose by the rabbit lens in the presence and absence of oxygen

1965 • 55 citations

High molecular weight protein from human lenses

1976 • 55 citations

Phase diagram for cell cytoplasm from the calf lens

1980 • 55 citations

Polyribosomes from calf-lens epithelium

1966 • 55 citations

Climatic Droplet Keratopathy

1973 • 55 citations

Collagen crosslinks: Isolation of reduced Nϵ-hexosylhydroxylysine from borohydride-reduced calf skin insoluble collagen

1972 • 54 citations

Acidic peptides of the lens. 5. S-Sulphoglutathione

1959 • 54 citations

Analysis of individual cataract patients and their lenses: A progress report

1980 • 54 citations

The yellow colour of the lens of the grey squirrel (Sciurus carolinensis leucotis)

1969 • 54 citations

Rat lens superoxide dismutase and glucose-6-phosphate dehydrogenase: Studies on the catalytic activity and the fate of enzyme antigen as a function of age

1981 • 54 citations

Influence of the pituitary on Wolffian lens regeneration

1973 • 54 citations

The changing cellular localization of α-crystallin in the lens of the chicken embryo, studied by immunofluorescence

1967 • 54 citations

The effect of X-irradiation on cation transport in rabbit lens

1981 • 53 citations

Multiple gamma-crystallins of the mouse lens: fractionation of mRNAs by cDNA cloning.

1982 • 53 citations

Comparative and Evolutionary Aspects of delta-Crystallin in the Vertebrate Lens

1979 • 53 citations

Variations in the carbohydrate content of human and bovine polymeric collagens from various tissues

1969 • 53 citations

Primary Structures of the alpha-Crystallin A Chains of Seven Mammalian Species

1975 • 53 citations

Cleavage of lens protein-GSH mixed disulfide by glutathione reductase

1973 • 53 citations

On the occurrence of microtubules in the developing lens of the squid Loligo pealii

1966 • 53 citations

DOES KERATOMALACIA EXIST IN ADULTS?

1929 • 53 citations

Neutral proteinases in the lens

1962 • 53 citations

Acidic peptides of the lens. 4. The biosynthesis of ophthalmic acid

1958 • 53 citations

Contribution to the Histopathology of Cataract

1955 • 53 citations

Lens Fluorescence in Aging and Cataract Formation

1976 • 53 citations

The β-crystallin bp chain is internally duplicated and homologous with γ-crystallin

1980 • 52 citations

Properties of a cold-precipitable protein fraction in the lens

1965 • 52 citations

Syneresis and its possible role in cataractogenesis

1979 • 52 citations

Evolution and diversity of the crystallins. Nucleotide sequence of a beta-crystallin mRNA from the mouse lens.

1982 • 52 citations

The alpha and gamma crystallin content in aqueous humor of eyes with clear lenses and with cataracts

1979 • 52 citations

Human lens fiber cell plasma membranes. I. Isolation, polypeptide composition and changes associated with ageing

1980 • 52 citations

Gel filtration of the soluble proteins from normal and cataractous human lenses

1965 • 52 citations

‘Shrivelled’: a hereditary degeneration of the lens in the house mouse

1962 • 52 citations

Metal-dependent proteinase of the lens. Assay, purification and properties of the bovine enzyme

1975 • 52 citations

Amizol-Induced Cataract and Inhibition of Lens Catalase in Rabbit

1973 • 52 citations

Light extinction and protein in lens

1976 • 52 citations

Species Differences in the Radiosensitivity of the Lens*

1957 • 51 citations

Synthesis of Lens Protein in vitro

1973 • 51 citations

Changes in proteins of the human lens in development and aging

1975 • 51 citations

High molecular weight protein aggregates in X-ray-induced cataract

1978 • 51 citations

Kayser-Fleischer Ring and Associated Cataract in Wilson's Disease

1975 • 51 citations

Herpes Simplex Virus-Induced Congenital Cataracts

1971 • 51 citations

Inhibition of the red cell calcium pump by quercetin

1980 • 50 citations

Possible roles of near UV light in the cataractous process

1973 • 50 citations

Lens Glycoproteins: Biosynthesis in Cultured Epithelial Cells of Bovine Lens

1975 • 50 citations

CLASSIFICATION OF EXPERIMENTAL CATARACTS IN THE RAT

1943 • 50 citations

Degradation of δ-crystallin mRNA in the lens fiber cells of the chicken

1982 • 50 citations

Changes in lipid distribution in the human lens with the development of cataract

1981 • 50 citations

THE DIFFERENTIATION OF PIGMENT CELLS IN CULTURES OF CHICK EMBRYONIC NEURAL RETINAE

1975 • 50 citations

Cyanate-Induced Cataracts in Patients With Sickle-Cell Hemoglobinopathies

1976 • 50 citations

Possible reactions of 1,2-naphthaquinone in the eye

1967 • 49 citations

A note on a possible relation between refraction and a disposition for senile nuclear cataract.

1980 • 49 citations

Galactokinase Deficiency and Cataracts

1972 • 49 citations

Purification of alditol:NADP oxidoreductase from human placenta

1972 • 49 citations

ULTRASTRUCTURAL CHANGES IN THE NORMAL HUMAN LENS CAPSULE FROM BIRTH TO OLD AGE

1974 • 49 citations

The Effects of Microwave Diathermy On the Eye*

1950 • 49 citations

Differential synthesis and degradation of protein in the hereditary Philly mouse cataract

1980 • 49 citations

BIOCHEMISTRY OF THE LENS

1936 • 49 citations

Naturally Occurring Peptides

1966 • 49 citations

AGING OF α-CRYSTALLINS DURING DEVELOPMENT OF THE LENS

1969 • 49 citations

Ultrastructural changes during the development and reversal of galactose cataracts

1978 • 49 citations

On the calcium concentration of cataractous and normal human lenses and protein fractions of cataractous lenses

1976 • 48 citations

Biochemistry of Bovine Lens Proteins

1972 • 48 citations

Distribution of non-diffusible calcium and sodium in normal and cataractous human lenses

1977 • 48 citations

Experimental cataract production by high frequency ultrasound.

1978 • 48 citations

CONTENT AND STATE OF GLUTATHIONE IN THE TISSUES OF THE EYE

1945 • 48 citations

Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses

1977 • 48 citations

Dimethyl Sulfoxide: Lens Changes in Dogs during Oral Administration

1966 • 48 citations

Microwave Lens Effects in Humans

1972 • 48 citations

?-Crystallin gene expression in embryonic chick lens epithelia cultured in the presence of insulin

1977 • 48 citations

Deficiency of Functional Messenger RNA for a Developmentally Regulated β-Crystallin Polypeptide in a Hereditary Cataract

1982 • 48 citations

Differentiation of lens and pigment cells in cultures of neural retinal cells of early chick embryos

1977 • 48 citations

Spontaneous Transformation of Bovine Lens Epithelial Cells

1978 • 48 citations

Studies on the crystalline lens. IV. Distribution of cytochrome, total riboflavin, lactate, and pyruvate and their metabolic significance.

1951 • 47 citations

Assay of fluorescent glucosides in the human lens

1973 • 47 citations

Chicken lens development: Epithelial cell production and migration

1966 • 47 citations

Light scattering of normal human lens. II. Age dependence of the light scattering parameters

1981 • 47 citations

OCULAR EFFECTS OF ORAL AND DERMAL APPLICATION OF DIMETHYL SULFOXIDE IN ANIMALS

1967 • 47 citations

Comparison of the 10 000 and 43 000 dalton polypeptide populations isolated from the water soluble and insoluble fractions of human cataractous lenses

1979 • 47 citations

Galactitol and galactose-1-phosphate in the lens of a galactosemic infant

1967 • 47 citations

Red fluorescence in older and brunescent human lenses.

1979 • 47 citations

Lens Proteins*

1957 • 46 citations

Possible demonstration of multipotential nature of embryonic neural retina by clonal cell culture

1979 • 46 citations

On the Quaternary Structure of High-Molecular-Weight Proteins from the Bovine Eye Lens

1975 • 46 citations

Acidic peptides of the lens. 8. S-(α β-dicarboxyethyl) glutathione

1963 • 46 citations

Neutral proteinase activity in the human lens

1976 • 46 citations

Raman spectra of bird and reptile lens proteins

1977 • 46 citations

Delta crystallin synthesis during chick lens differentiation

1973 • 45 citations

OUTCOME OF CATARACT SURGERY I

1982 • 45 citations

CATARACTS PRODUCED IN ALBINO RATS ON A RATION CONTAINING A HIGH PROPORTION OF LACTOSE OR GALACTOSE

1935 • 45 citations

The quantitative analysis of ligand binding and initial-rate data for allosteric and other complex enzyme mechanisms

1976 • 45 citations

Isolation and characterization of aldose reductase from calf brain

1976 • 45 citations

Cyanate formation in solutions of urea II. Effect of urea on the eye lens protein α-crystallin

1971 • 45 citations

Selective reassociation of the crystallins

1975 • 45 citations

Senile cataract extraction and diabetes.

1976 • 45 citations

STUDIES ON THE CRYSTALLINE LENS

1950 • 45 citations

Morphogenesis of the eye lens in a mouse strain with hereditary cataracts

1968 • 45 citations

Nonenzymatic glycosylation of human hemoglobin at multiple sites

1979 • 44 citations

The occurrence of senile cataracts, ocular hypertension and glaucoma in rhesus monkeys

1982 • 44 citations

Conformation of gamma-crystallins of the calf lens: Effects of temperature and denaturing agents

1977 • 44 citations

Paramagnetic species in cataractous human lenses

1975 • 44 citations

Differential synthesis of crystallin and noncrystallin polypeptides during lens fiber cell differentiation in vitro

1976 • 44 citations

Steroid Cataracts

1965 • 44 citations

mesoInositol in the lens of mammalian eyes

1957 • 44 citations

Superoxide dismutase activities of bovine ocular tissues

1978 • 44 citations

N-terminal acetylation of the nascent chains of α-crystallin

1974 • 44 citations

Evolutionary changes ofα-crystallin and the phylogeny of mammalian orders

1977 • 44 citations

Alloxan Diabetes and the Lens*

1950 • 44 citations

Effect of aging on the water-soluble and water-insoluble protein pattern in normal human lens

1982 • 44 citations

Protein synthesis in embryonic chick lens cells

1967 • 44 citations

Changes in myo-inositol permeability in the lens due to cataractous conditions

1968 • 43 citations

The Optical Rotatory Dispersion and Circular Dichroism of Calf Lens α-Crystallin

1967 • 43 citations

Variation of the concentration of sulfhydryl along the visual axis of aging lenses by laser Raman optical dissection technique

1979 • 43 citations

Naphthalene cataract in rats and rabbits: A resumé

1979 • 43 citations

Leucine aminopeptidase (bovine lens). Effect of pH on the relative binding of Zn2+ and Mg2+ to and on activation of the enzyme.

1976 • 43 citations

The measurement and interpretation of Brillouin scattering in the lens of the eye

1982 • 43 citations

Immunofluorescent study of a chick lens fiber cell membrane polypeptide

1978 • 43 citations

Immunochemical studies on albuminoid

1968 • 43 citations

Ah Locus: Genetic Differences in Susceptibility to Cataracts Induced by Acetaminophen

1978 • 42 citations

Triparanol-induced Cataract in Rats.

1963 • 42 citations

Alterations of lens protein synthesis in galactosemic rats.

1979 • 42 citations

The primary structure of the B₂ chain of human α‐crystallin

1977 • 42 citations

Location of a gene controlling electrophoretic variation in mouse γ-crystallins

1982 • 42 citations

The Role of DNA damage, its Repair and its Misrepair in the Etiology of Cataract: a Review

1978 • 42 citations

Cell Shape Regulation and Cell Cycle in Embryonic Lens Cells

1974 • 42 citations

Clinical findings, course, and progress of Bietti's corneal degeneration in the Dahlak islands.

1973 • 42 citations

The polypeptide chains of α-crystallin from old human eye lenses

1978 • 42 citations

Thioacetamide-induced cataract with invasive proliferation of the lens epithelium in rainbow trout.

1966 • 41 citations

β-Crystallins of the adult chicken lens: Relatedness of the polypeptides and their aggregates

1980 • 41 citations

Biochemical and structural features of chick lens gap junctions

1981 • 41 citations

BIOCHEMISTRY OF THE LENS

1938 • 41 citations

The reaggregation of purified subunits of alpha-crystallin

1973 • 41 citations

Possible Relationship of Ethylene Oxide Exposure to Cataract Formation

1982 • 41 citations

Transcription and site-specific hypomethylation of the delta-crystallin genes in the embryonic chicken lens.

1981 • 41 citations

Cytoplasmic RNA sequences complementary to cloned chick δ-crystallin cDNA show size heterogeneity.

1982 • 41 citations

Studies on the low molecular weight proteins of human lens

1981 • 41 citations

Fine-structural changes associated with lens determination in the avian embryo

1961 • 41 citations

Cytoplasmic phase separation in formation of galactosemic cataract in lenses of young rats

1979 • 41 citations

Inhibition of lens and cataract aldose reductase by protein-bound anti-rheumatic drugs: Salicylate, indomethacin, oxyphenbutazone, sulindac

1982 • 41 citations

β-crystallin mRNAs: Differential distribution in the developing chicken lens

1981 • 40 citations

Characterization of hydrophobic regions in proteins by spin labeling technique

1973 • 40 citations

A preliminary report on the amino acid composition of the pseudo-exfoliation material (PE material)

1973 • 40 citations

Composition of the Polysaccharide of the Lens Capsule and its Topical Distribution*

1954 • 40 citations

Synthesis of Lens Protein in vitro

1973 • 40 citations

Opacities in the Lens of the Eye Experimentally Induced by Exposure to Microwave Radiation

1960 • 40 citations

LENTICULAR AND RETINAL CHANGES SECONDARY TO MICROWAVE EXPOSURE

1973 • 40 citations

Eye and skin changes in psychiatric patients treated with chlorpromazine.

1967 • 40 citations

γ-Glutamyl-cysteine synthetase from bovine lens

1967 • 40 citations

Phospholipid composition and metabolism in the embryonic chick lens

1978 • 40 citations

Primary Spheroidal Degeneration of the Cornea in Labrador and Northern Newfoundland

1975 • 40 citations

Translational regulation of δ-crystallin synthesis during lens development in the chicken embryo

1981 • 40 citations

Lens‐formation from strange ectoderm in rana sylvatica

1907 • 40 citations

Changes in membrane protein pattern in relation to lens cell differentiation

1977 • 40 citations

Immunofluorescence Studies of Chick Lens FISC and α-Crystallin Antigens during Lens Morphogenesis and Development

1971 • 40 citations

The effect of an unsaturated-fat diet on cataract formation in streptozotocin-induced diabetic rats

1976 • 40 citations

EXPERIMENTAL MANIPULATION OF ALTERNATIVE PATHWAYS OF DIFFERENTIATION IN CULTURES OF EMBRYONIC CHICK NEURAL RETINA

1977 • 39 citations

Isolation and characterization of covalently linked, high molecular weight proteins from human cataractous lens

1977 • 39 citations

On the possible role of glutathione in maintaining human lens protein sulphydryls

1979 • 39 citations

Structure-activity studies of aldose reductase inhibitors containing the 4-oxo-4H-chromen ring system

1978 • 39 citations

One-step separation of the subunits of α-crystallin by chromatofocusing in 6 m urea

1981 • 39 citations

THE PRENATAL GROWTH OF THE HUMAN EYE

1968 • 39 citations

Molecular sieve effect of the blood-aqueous barrier

1975 • 39 citations

Fractionation of the water-insoluble proteins from calf lens

1979 • 39 citations

Pathogenetic Factors in Experimental Galactose Cataract

1960 • 39 citations

Struktur- und Wirkungsidentität der Leucinaminopeptidase aus Schweinenieren und Rinderaugenlinsen und Vergleich mit der Partikelaminopeptidase aus Schweinenieren

1967 • 39 citations

Phospholipids in the tissues of the eye. II. Composition and incorporation of 32Pi of phospholipids of normal rat and calf lens.

1968 • 39 citations

Properties of the crystallins of the chick in terms of their subunit composition

1969 • 39 citations

X-ray induced cataract in rabbit lens

1975 • 39 citations

The Relative Radiosensitivity of Rat Lenses as a Function of Age

1975 • 39 citations

Lens Changes in Chronic Granulocytic Leukemia

1969 • 39 citations

Use of Guinea Pigs as Model to Study Galactose-Induced Cataract Formation

1978 • 39 citations

STUDIES ON THE CRYSTALLINE LENS

1952 • 39 citations

Modelling cortical cataractogenesis: 2. In vitro effects on the lens of agents preventing glucose- and sorbitol-induced cataracts.

1981 • 39 citations

Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses.

1978 • 39 citations

A steady-state-kinetic model for formaldehyde dehydrogenase from human liver. A mechanism involving NAD+ and the hemimercaptal adduct of glutathione and formaldehyde as substrates and free glutathione as an allosteric activator of the enzyme

1979 • 39 citations

A geographic approach to senile cataracts

1982 • 39 citations

Synthesis of lens protein in vitro V. Isolation of messenger‐like RNA from lens by high resolution zonal centrifugation

1971 • 39 citations

Fluorescent derivatives of 3-hydroxy-<scp>L</scp>-kynurenine in the lens of man, the baboon and the grey squirrel

1971 • 39 citations

Aldose Reductase from Rhodotorula

1971 • 38 citations

Cytodifferentiation of precultured embryonic chick lens epithelial cells in vitro and in vivo

1968 • 38 citations

In vitro synthesis of the major lens membrane protein.

1980 • 38 citations

Lactate Dehydrogenase Isozyme Patterns of Human Platelets and Bovine Lens Fibers

1965 • 38 citations

Properties of a cryoprotein in the ocular lens

1966 • 38 citations

The state of sulfhydryl groups in normal and cataractous human lens proteins. II. Cortical and nuclear regions

1979 • 38 citations

Purification and properties of glutathione peroxidase from bovine lens

1968 • 38 citations

Characteristics of α-crystallin related to fiber cell development in calf eye lenses

1973 • 38 citations

Aldose reductase and sorbitol dehydrogenase distribution in substructures of normal and diabetic rat lens.

1977 • 38 citations

Receptors for Glucocorticoids in the Lens Epithelium of the Calf

1978 • 38 citations

Protein distribution and characterization in the prenatal and postnatal human lens

1982 • 38 citations

Comparison of polyunsaturated fatty acid levels in normal and mature cataractous human lenses

1982 • 38 citations

Acid-soluble phosphates in the lens

1958 • 38 citations

Isolation and cell-free translation of chick lens crystallin mRNA during normal development and transdifferentiation of neural retina

1978 • 38 citations

Localization of gamma-glutamyl transpeptidase in rabbit lens, ciliary process and cornea

1973 • 38 citations

Nature and origin of the insoluble protein of rat lens

1969 • 38 citations

Biochemical Studies on Cataract*

1957 • 37 citations

A comparison of human lens epithelial cells in situ and in vitro in relation to aging: an ultrastructural study

1979 • 37 citations

The Distribution of Glutathione and Protein Sulfhydryl Groups in Calf and Cattle Lenses*

1958 • 37 citations

DINITROPHENOL AND ITS RELATION TO FORMATION OF CATARACT

1942 • 37 citations

Subunit characterization of lens intermediate filaments

1980 • 37 citations

Lens Cataract Formation and Reversible Alteration in Crystallin Synthesis in Cultured Lenses

1977 • 37 citations

Antigens of the lens of Xenopus laevis

1968 • 37 citations

Electronmicroscopical, histochemical and biochemical findings on the Na-K-ATPase activity in the epithelium of the rat lens

1976 • 37 citations

Eye lens opacity in cortical cataracts associated with actin-related globular degeneration

1979 • 37 citations

Age and cataract-related changes in the heavy molecular weight proteins and gamma crystallin composition of the mouse lens

1979 • 37 citations

Nuclear magnetic resonance studies of the unfolding of pancreatic ribonuclease

1975 • 37 citations

The in vitro development of lens from cornea of larval Xenopus laevis

1968 • 37 citations

STUDIES ON THE CRYSTALLINE LENS

1951 • 37 citations

The chemistry of sheep anterior lens capsule

1970 • 36 citations

The Identification of Anthranilic Acid in Proteolytic Digests of Cataractous Lens Proteins

1977 • 36 citations

Physical-chemical studies on bovine eye lens proteins

1982 • 36 citations

Isolation and identification of chick lens crystallin messenger RNA

1972 • 36 citations

Studies on the reaggregation of isolated subunits of calf lens alpha-crystallin

1972 • 36 citations

[INVESTIGATIONS ON LENS PROTEIN AND MICROELECTROPHORESIS OF HYDROSOLUBLE PROTEIN IN SENILE CATARACT].

1963 • 36 citations

Changes in phosphatidylinositol metabolism during differentiation of lens epithelial cells into lens fiber cells in the embryonic chick.

1980 • 36 citations

Lens differentiation from the cornea following lens extirpation or cornea transplantation in Xenopus laevis

1973 • 36 citations

Cultured calf lens epithelium. II. The effect of dexamethasone

1974 • 36 citations

High purification of the RNase inhibitor from rat liver by affinity chromatography

1970 • 36 citations

Lipid composition and ( activity in rat lens during triparanol-induced cataract formation

1981 • 36 citations

Erythrocyte Spectrin Glucosylation in Diabetes

1982 • 36 citations

Cataracts in Vitamin E Deficiency

1956 • 36 citations

Estimation of the molecular weights of chick β- and δ-crystallins and their subunits by gel filtration

1971 • 36 citations

Hypophysectomy Effect on Lens Epithelium Mitosis and Galactose Cataract Development in Rats

1962 • 36 citations

The topography of lens proteins based on chromatography and two-dimensional gel electrophoresis

1975 • 36 citations

Evidence for two sodium pumps in the crystalline lens of the rabbit eye

1978 • 36 citations

Metabolism of xylose by the lens. Calf lens in vitro

1958 • 35 citations

Relationships between eye factors and lens-forming transformations in the cornea and pericorneal epidermis of larvalXenopus laevis

1979 • 35 citations

Cataracts in the aging rat lens. Morphology and acid phosphatase histochemistry of incipient forms

1978 • 35 citations

Effect of Lid Closure in Drug-Induced Experimental Cataracts

1966 • 35 citations

Tubulin carbamoylation. Functional amino groups in microtubule assembly

1982 • 35 citations

IN VITRO PRODUCTION OF STEROID CATARACT IN BOVINE LENS

1979 • 35 citations

Regulation of blood ammonia.

1978 • 35 citations

SV40-transformed hamster lens epithelial cells: A novel system for the isolation of cytoskeletal messenger RNAs and their translation products

1980 • 35 citations

Picosecond light scattering measurements of cataract microstructure

1978 • 35 citations

Electric Cataracts

1972 • 34 citations

CATARACTS OF CHRONIC RENAL FAILURE

1972 • 34 citations

The effect of light on lens proteins in vitro

1972 • 34 citations

RETINAL DAMAGE EXPERIMENTALLY INDUCED BY MICROWAVE RADIATION AT 55 mW/cm²

1979 • 34 citations

Lens plasma membrane: Isolation and biochemical characterization

1982 • 34 citations

Metabolism of amino acids in the lens

1964 • 34 citations

Inhibition of action of lens mutarotase on glucose by cataractogenic sugars and corresponding polyols

1963 • 34 citations

Synthesis of Lens Protein in vitro: Formation of beta-Crystallin

1977 • 34 citations

Transport of l-glutamic acid and l-glutamine and their incorporation into lenticular glutathione

1973 • 34 citations

MATERNAL ENZYMES OF GALACTOSE METABOLISM AND THE "INEXPLICABLE" INFANTILE CATARACT

1974 • 34 citations

Further studies on the purification and properties of a ribonuclease inhibitor from lens cortex

1972 • 34 citations

Effect of cyclic AMP, caffeine and theophylline on differentiation of lens epithelial cells

1974 • 34 citations

Characterization of lens proteins. II. γ-Crystallin of normal and cataractous rat lenses

1978 • 33 citations

In vitro glycosylation of hemoglobins by different sugars and sugar phosphates

1978 • 33 citations

Three classes of sulfhydryl group in bovine α-crystallin according to reactivity to various reagents

1978 • 33 citations

Sequence complexity and tissue distribution of chick lens crystallin mRNAs

1978 • 33 citations

Experimental Miotic Cataract

1968 • 33 citations

EFFECTS OF BETA IRRADIATION ON THE RABBIT LENS

1953 • 33 citations

A chalone in the rabbit lens?

1968 • 33 citations

α-, β- and γ- Crystallins in the regenerating lens of Notophthalmus viridescens

1982 • 33 citations

Ocular Involvement in Cutaneous Porphyria

1971 • 33 citations

The function of the metal ion in leucine aminopeptidase and the mechanism of action of the enzyme

1964 • 33 citations

Studies on the assembly of the rat lens capsule. Biosynthesis of a cross-linked collagenous component of high molecular weight

1980 • 33 citations

Structural studies of α-crystallin

1965 • 33 citations

An unusually long non-coding region in rat lens α-crystallin messenger RNA

1981 • 33 citations

DNA synthesis and repair in terminally differentiating embryonic lens cells

1977 • 33 citations

N-terminal groups of lens proteins

1968 • 32 citations

The antigenic structure of chick β-crystallin subunits

1974 • 32 citations

Pathology of cataracts in mongoloid idiocy

1962 • 32 citations

Tryptophan-Deficiency Cataract in Guinea Pigs

1959 • 32 citations

Presence and metabolism of amino acids in young and old lenses

1962 • 32 citations

STUDIES ON THE CRYSTALLINE LENS

1950 • 32 citations

Experimental traumatic cataract. II. A transmission electron microscopy and extracellular tracer study.

1979 • 32 citations

Stereospecificity of the hydrogen transfer catalyzed by human placental aldose reductase

1977 • 32 citations

A change in α-crystallin subunit composition in relation to cellular differentiation in adult bovine lens

1970 • 32 citations

EFFECTS OF ULTRASONIC WAVES ON THE REFRACTIVE MEDIA OF THE EYE

1952 • 32 citations

Lens Opacification in Mice Exposed to 14-MeV Neutrons

1978 • 32 citations

The molecular weight of the 14S calf lens messenger RNA

1974 • 32 citations

Lens Organ Culture

1967 • 32 citations

NSF's Bid for Relevance

1972 • 32 citations

The Quaternary Structure of Bovine α‐Crystallin

1980 • 32 citations

Electric Cataracts

1972 • 32 citations

The exfoliation syndrome.

1976 • 32 citations

Influence of a prolonged period of low-dosage x-rays on the optic and ultrastructural appearances of cataract of the human lens.

1979 • 32 citations

Human α-crystallin. II. Characterization of the protein isolated from the periphery of cataractous lenses

1976 • 31 citations

Age-related changes in the polypeptide composition of β-crystallin from bovine lens

1978 • 31 citations

Reactions of Biologic Aldehydes with Proteins

1982 • 31 citations

Reflections on the internal primary, secondary and tertiary structure homology of the eye lens proteins α‐,β‐ and γ‐crystallin

1981 • 31 citations

Affinity chromatography in the purification of glutathione reductase

1973 • 31 citations

EFFECT OF AGE AND DIET ON DEVELOPMENT OF CATARACTS IN THE DIABETIC RAT

1950 • 31 citations

Diminished sugar cataractogenesis by quercetin

1979 • 31 citations

Cyanate Inhibition of Erythrocyte Glucose-6-phosphate Dehydrogenase

1972 • 31 citations

Effect of various agents on drug-induced opacities of the lens

1967 • 31 citations

Effects of sucrose on interactions of calf lens soluble proteins

1978 • 31 citations

Metabolism of red cell glutathione

1971 • 31 citations

Fine structure, origin and fate of extracellular materials in the interspace between the presumptive lens and presumptive retina of the chick embryo.

1974 • 31 citations

Low molecular weight proteins of the bovine lenses

1977 • 31 citations

Effects of vitamin E on cortical cataractogenesis induced by elevated temperature in intact rat lenses in medium 199

1981 • 31 citations

Altered heat-lability of a fraction of glutathione reductase in aging human lens

1973 • 31 citations

[63] Translation of mRNA from vertebrate eye lenses

1974 • 31 citations

Investigations on trace elements in normal and senile cataractous lenses

1977 • 31 citations

EXPERIMENTAL RADIATION CATARACT

1952 • 31 citations

Purification and properties of bovine lens glutathione S-transferase

1980 • 31 citations

Role of sulfhydryl groups in the formation of a hereditary cataract in the rat

1975 • 30 citations

In vitro differentiation of cells of the lens epithelium of human fetus

1978 • 30 citations

Lenticular Opacities in Young Rats as a Consequence of Maternal Diets Low in Tryptophan and/or Vitamin E

1976 • 30 citations

STUDIES ON THE ANTIGENIC STRUCTURE OF THE EYE USING THE FLUORESCENT ANTIBODY TECHNIQUE

1957 • 30 citations

Actin in the lens: Changes in actin during differentiation of lens epithelial cells in vivo

1979 • 30 citations

Growth and cytodifferentiation of embryonic chick lens epithelial cells in vitro

1970 • 30 citations

Growing Insight into the Structure of β-crystallin

1974 • 30 citations

Inhibition of Sugar Metabolism in the Lens

1954 • 30 citations

The human lens

1972 • 30 citations

On the existence of γ-crystallin in the bird lens

1977 • 30 citations

A retrospective study of cataract formation in 96 patients treated with PUVA

1982 • 30 citations

Physical and chemical changes in alpha-crystallin during maturation of lens fibers

1974 • 30 citations

Studies on biosynthesis of soluble lens crystallin antigens in the chick by isoelectric focusing in thin-layer polyacrylamide gel

1976 • 30 citations

Development of the optical surfaces of the kitten eye

1978 • 30 citations

Galactose cataract in riboflavin deficient rats

1972 • 30 citations

Time/Dose Relationships in Experimental Radiation Cataractogenesis

1975 • 30 citations

PERMEABILITY OF THE CAPSULE FOR THE LENS‐PROTEINS

1958 • 30 citations

The nucleotide sequence of a cloned cDNA corresponding to one of the γ‐crystallins from the eye lens of the frog Rana temporaria

1982 • 30 citations

The isolation and partial structural characterization of some ocular gangliosides

1970 • 30 citations

Purification and properties of calf liver aldose reductase

1974 • 29 citations

Sorbitol and other polyols in lens, adipose tissue and urine in diabetes mellitus

1975 • 29 citations

Malorientation of mitotic figures in the early lens rudiment of aphakia mouse embryos

1975 • 29 citations

Transport of organic molecules in the lens

1973 • 29 citations

Study on Penetration of Cysteine and Cystine into the Aqueous Humor of Rabbits and its Relation to Early X-Irradiation Effects on the Eye*

1951 • 29 citations

Delta-crystallin synthesis by the adult chicken lens

1981 • 29 citations

Soft-tissue Effects Following 224Ra Injections Into Humans

1978 • 29 citations

Osmotic influences on lens membrane characteristics

1980 • 29 citations

The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy

1973 • 29 citations

Ontogeny and localization of the α, β, and γ crystallins in newt eye lens development

1981 • 29 citations

Neutral proteinases in the lens. 2. Partial purification and properties

1963 • 29 citations

Evidence of two soluble RNA types in eye lens

1964 • 29 citations

Partial dissociation and renaturation of embryonic chick δ-crystallin. Characterization by ultracentrifugation and circular dichroism

1977 • 29 citations

ALKALINE PHOSPHATASE IN THE DORSAL AND THE VENTRAL HALVES OF THE IRIS DURING EARLY STAGES OF LENS-REGENERATION IN THE NEWT

1963 • 29 citations

Galactose cataract: A review

1971 • 29 citations

Inactivation of catalase by near ultraviolet light and tryptophan photoproducts.

1976 • 29 citations

The control of δ-crystallin gene expression during lens cell development: Dissociation of cell elongation, cell division, δ-crystallin synthesis, and δ-crystallin mRNA accumulation

1977 • 29 citations

γ-Glutamyl-cysteine synthetase from bovine lens

1967 • 29 citations

Increased Incidence of Cataracts in Male Subjects Deficient in Glucose-6-Phosphate Dehydrogenase

1981 • 29 citations

Human senile cataractous lens protease. Isolation and some chemical characteristics

1971 • 29 citations

The role of respiration in the energy metabolism of the bovine lens

1972 • 29 citations

Thickness and volume constants and ultrastructural organization of basement membrane (lens capsule).

1979 • 29 citations

OCULAR DEVELOPMENT AND INVOLUTION IN THE EUROPEAN CAVE SALAMANDER,PROTEUS ANGUINUSLAURENTI

1976 • 29 citations

Accumulation of copper and inhibition of lactate dehydrogenase activity in human senile cataractous lens.

1969 • 29 citations

Induction of mitosis in the cultured rabbit lens initiated by the addition of insulin to medium KEI-4

1975 • 28 citations

Eye Lens Nucleotides of Different Species of Vertebrates

1965 • 28 citations

Bovine lens γ-glutamyl transpeptidase

1973 • 28 citations

Organophosphate metabolites of the human and rabbit crystalline lens: a phosphorus-31 nuclear magnetic resonance spectroscopic analysis

1982 • 28 citations

Heterogeneity of collagens from basement membranes of lens and cornea

1977 • 28 citations

Studies on the subunits of α-crystallin and their recombination

1964 • 28 citations

Calf lens messenger ribonucleoprotein complexes

1976 • 28 citations

Aging effects on the bovine lens γ-crystallins

1974 • 28 citations

Immunofluorescent studies on aphakia, a mutation of a gene involved in the control of lens differentiation in the mouse embryo

1975 • 28 citations

Method of Visualization of Matrix-Bound Proteins. Leucine Aminopeptidase Bound to Sepharose and Sephadex Beads

1972 • 28 citations

Internally elongated rodent α-crystallin A chain: Resulting from incomplete RNA splicing?

1980 • 28 citations

Lens Soluble Proteins: Correlation with the Cytological Differentiation in the Young Adult Organ of the Chick

1968 • 28 citations

Phospholipid distributions and fatty acid composition of lysophosphatidylcholine and phosphatidylcholine in rabbit aqueous humor, lens and vitreous

1976 • 28 citations

Experimental Miotic Cataract

1968 • 28 citations

Mammalian lens dipeptidyl aminopeptidase III

1978 • 28 citations

Phospholipids in the tissues of the eye

1968 • 28 citations

ULTRA‐VIOLET RADIATION AS A POSSIBLE CAUSE OF CORNEAL DEGENERATIVE CHANGES UNDER CERTAIN PHYSIOGRAPHIC CONDITIONS

1974 • 28 citations

Evolutionary and developmental differences in delta-crystallin from bird and reptile lenses Circular dichroism and fluorescence studies

1980 • 27 citations

ULTRASTRUCTURAL LENS CHANGES IN X‐RAY INDUCED CATARACT OF THE RAT

1978 • 27 citations

Sugar-induced change in near ultraviolet circular dichroism of α-crystallin

1981 • 27 citations

On reproduction studies and the occurrence of cataracts in rats after long-term feeding of the insecticide hepatchlor

1967 • 27 citations

The isolation of S-sulphoglutathione from the small intestine of the rat

1964 • 27 citations

DIARRHOEAL DISEASE IN ABORIGINAL AND NON‐ABORIGINAL INFANTS AND YOUNG CHILDREN IN WESTERN AUSTRALIA

1981 • 27 citations

Specific antiserum to the main intrinsic polypeptide of chick lens fiber cell plasma membranes

1978 • 27 citations

Failure of growth regulation of the lens epithelium in strains of fast-growing chicks

1975 • 27 citations

Subunit structure of bovine α-crystallin and albuminoid

1968 • 27 citations

HM-crystallin as an intermediate in the conversion of water-soluble into water-insoluble rabbit lens proteins

1974 • 27 citations

Phospholipids of the human lens

1966 • 27 citations

Cell elongation and δ-crystallin synthesis without RNA synthesis in cultured early embryonic chick lens epithelia

1973 • 27 citations

Protein Synthesis and Polyribosomes in the Calf Lens

1966 • 27 citations

Changes in Mineral Composition of Rat Lenses with Galactose Cataract*

1942 • 27 citations

Crystallin synthesis and crystallin mRNAs in galactosemic rat lenses

1982 • 27 citations

Ocular Manifestations of Group A Niemann-Pick Disease

1978 • 27 citations

Cataractogenic Effect of Corticosteroids on Animals

1968 • 27 citations

Induction of an Experimental Tumour of the Lens

1947 • 27 citations

The poly A content and secondary structure of the 14S calf lens messenger RNA

1974 • 27 citations

Some glycolytic enzymes and intermediates in the rabbit lens

1965 • 26 citations

Allosteric and related phenomena: An analysis of sigmoid and non-hyperbolic functions

1975 • 26 citations

Biologie du cristallin

1955 • 26 citations

CHEMISTRY OF THE LENS

1933 • 26 citations

Effect of experimental diabetes on glycolytic intermediates and regulation of phosphofructokinase in rat lens

1980 • 26 citations

DNA repair in lens cells during chick embryo development

1979 • 26 citations

Ophthalmological complications of haemodialysis and kidney transplantation

1980 • 26 citations

Human lens epithelium in tissue culture: Biochemical and morphological aspects

1982 • 26 citations

Carcinogenic nitrosamides and cell cultures

1976 • 26 citations

Activation of proteinases with trypsin-like specificity from bovine and human lenses

1981 • 26 citations

Transport and metabolism of glutathione in the lens

1973 • 26 citations

Investigation of Nakano lens proteins

1982 • 26 citations

Incidence of Cataracts in Rhesus Monkeys Treated with Whole-Body Irradiation

1979 • 26 citations

Proteins and Protein Synthesis in Rat Lenses with Galactose Cataract

1956 • 26 citations

Aqueous humor in lens repair and cell proliferation

1976 • 26 citations

Preliminary X-ray study of leucine aminopeptidase (bovine lens), an oligomeric metalloenzyme

1977 • 26 citations

Contributions to the Enzymology of the Normal and Cataractous Lens

1953 • 26 citations

Diquat cataract: Formation of the free radical and its reaction with constituents of the eye

1970 • 26 citations

Influence of Microwaves on Certain Enzyme Systems in the Lens of the Eye*

1951 • 26 citations

Glutathione peroxidase from bovine lens: a selenoenzyme

1982 • 26 citations

Development of Diabetic Cataracts*

1952 • 26 citations

Subcellular distribution of sphingomyelinase and other acid hydrolases in different parts of the calf lens

1974 • 26 citations

Lens membranes VI. Some characteristics of the EDTA-extractable protein (EEP) from bovine lens fiber membranes

1979 • 25 citations

Isoelectric focusing of embryonic cow lens crystallins

1973 • 25 citations

A study of three enzymes acting on glucose in the lens of different species

1967 • 25 citations

Calf lens neutral proteinase activity using calf lens crystallin substrates

1982 • 25 citations

The Protein Structure of Chick Lens Fiber Cell Membranes and Intracellular Matrix

1976 • 25 citations

The presence of polyriboadenylic acid sequences in calf lens messenger RNA

1974 • 25 citations

Observations on a Cytoplasmic Component in Lens Fibers

1960 • 25 citations

Lens-specific mRNA in cultures of embryonic chick neural retina and pigmented epithelium

1979 • 25 citations

Interpretation of Nonhyperbolic Behavior in Enzymic Systems. I. Differentiation of Model Mechanisms

1971 • 25 citations

Glucose-induced membrane permeability changes in the lens

1982 • 25 citations

Changes in Proteins and Protein Synthesis*

1959 • 25 citations

Gap junctions from the lens: Purification and characterization by chemical crosslinking reagent

1981 • 25 citations

Increase of non-disulphide cross-links during progress of nuclear cataract

1978 • 25 citations

The Nutritional Teamwork Approach: Prevention and Regression of Cataracts in Rats

1974 • 25 citations

Ocular Effects Produced by Experimental Lasers

1968 • 25 citations

Ergothioneine content in normal and senile human cataractous lenses.

1981 • 25 citations

Free isoelectric focusing of bovine lens γ-crystallins

1973 • 25 citations

Lens exopeptidases

1981 • 25 citations