Alternative splicing of alpha A-crystallin RNA. Structural and quantitative analyses of the mRNAs for the alpha A2- and alpha Ains-crystallin polypeptides.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Why genes in pieces?

1978 • 2,256 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Structural proteins of the mammalian lens: A review with emphasis on changes in development, aging and cataract

1976 • 482 citations

A single mouse α-amylase gene specifies two different tissue-specific mRNAs

1981 • 402 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

The Amino‐Acid Sequence of the αA₂ Chain of Bovine α‐Crystallin

1973 • 304 citations

Molecular Aspects of Lens Cell Differentiation

1967 • 300 citations

Do genes-in-pieces imply proteins-in-pieces?

1978 • 287 citations

Splice Junctions: Association with Variation in Protein Structure

1983 • 261 citations

The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes

1981 • 260 citations

Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron

1983 • 251 citations

The Amino‐Acid Sequence of the αB₂ Chain of Bovine α‐Crystallin

1974 • 182 citations

Recombinant molecules: Impact on science and society

1978 • 143 citations

Gene and protein structure of a β-crystallin polypeptide in murine lens: relationship of exons and structural motifs

1983 • 121 citations

Abnormal RNA splicing causes one form of α thalassemia

1982 • 120 citations

The nucleotide sequence of the adult chicken alpha-globin genes.

1983 • 118 citations

Use of solubilizable acrylamide disulfide gels for isolation of DNA fragments suitable for sequence analysis

1981 • 91 citations

αA-Crystallin Messenger RNA of the Mouse Lens: More Noncoding Than Coding Sequences

1982 • 78 citations

Rat alpha-Crystallin A Chain with an Insertion of 22 Residues

1978 • 67 citations

Isolation and In Vitro Translation of δ-Crystallin mRNA from Embryonic Chick Lens Fibers

1974 • 62 citations

Primary Structures of the alpha-Crystallin A Chains of Seven Mammalian Species

1975 • 53 citations

In vitro synthesis of rat fibrinogen: identification of preA alpha, preB beta, and pre gamma polypeptides.

1981 • 47 citations

α-Crystallin polypeptides as markers of lens cell differentiation

1978 • 42 citations

Internally elongated rodent α-crystallin A chain: Resulting from incomplete RNA splicing?

1980 • 28 citations

Two Structurally Closely Related Polypeptides Encoded by 14-S mRNA Isolated from Rat Lens

1978 • 21 citations

Anion and cation effects on δ-crystallin synthesis in the cultured embryonic chick lens and in a reticulocyte lysate

1980 • 16 citations