Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes.

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1993 • 884 citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 • 698 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors.

1992 • 297 citations

MAMMALIAN GENES INDUCED BY RADIATION; Activation of Genes Associated with Growth Control

1992 • 284 citations

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.

1991 • 268 citations

Genetic complementation reveals a novel regulatory role for 3? untranslated regions in growth and differentiation

1993 • 245 citations

Transient translational silencing by reversible mRNA deadenylation

1992 • 239 citations

Analysis of the mammalian gadd45 gene and its response to DNA damage.

1993 • 231 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

AP1/ jun Function Is Differentially Induced in Promotion-Sensitive and Resistant JB6 Cells

1989 • 210 citations

Induction of fos RNA by DNA-damaging agents.

1989 • 209 citations

A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons.

1993 • 192 citations

Response to adversity: molecular control of gene activation following genotoxic stress.

1991 • 189 citations

Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells

1971 • 143 citations

Regulation of proto-oncogene mRNA stability

1992 • 111 citations

A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs

1991 • 77 citations

Estimation of Relative mRNA Content by Filter Hybridization to a Polyuridylic Probe

2000 • 72 citations

Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes

1990 • 72 citations

The Destabilizing Elements in the Coding Region of c-fos mRNA Are Recognized as RNA

1993 • 71 citations

DNA Repair and Its Pathogenetic Implications

1990 • 69 citations

Cell growth inhibition by prostaglandin A2 results in elevated expression of gadd153 mRNA

1992 • 41 citations

Abundance of the primary transcript and its processed product of growth-related genes in normal and leukemic cells during proliferation and differentiation.

1992 • 30 citations

Altered myc gene transcription and intron-induced stabilization of myc RNAs in two mouse plasmacytomas.

1989 • 24 citations