Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

1984 • 601 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

1991 • 468 citations

mRNA decay: Finding the right targets

1989 • 318 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts

1988 • 289 citations

Regulation of c-fosgene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation

1987 • 218 citations

Posttranscriptional regulation of c-fos mRNA expression

1987 • 215 citations

Trans-repression of the mouse c-fos promoter: A novel mechanism of fos-mediated trans-regulation

1989 • 187 citations

c-fos expression induces bone tumors in transgenic mice.

1989 • 177 citations

The inner core of the serum response element mediates both the rapid induction and subsequent repression of c-fos transcription following serum stimulation.

1990 • 146 citations

Negative regulation of serum-responsive enhancer elements

1989 • 144 citations

The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription.

1989 • 135 citations

Effect of Protein Synthesis Inhibitors on Growth Factor Activation of c-fos, c-myc, and Actin Gene Transcription

1986 • 132 citations

Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc.

1987 • 125 citations

Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements.

1985 • 120 citations

Modulation of c-"os gene transcription by negative and positive cellular factors

1987 • 110 citations

Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice

1990 • 109 citations

A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.

1986 • 109 citations

c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1.

1991 • 102 citations

Poly(A) Tail Shortening Is the Translation-Dependent Step in c-myc mRNA Degradation

1990 • 100 citations

Demonstration in living cells of an intragenic negative regulatory element within the rodent c-fos gene

1990 • 96 citations

Growth factor-responsive genes in fibroblasts.

1990 • 87 citations

Sequence requirements for premature transcription arrest within the first intron of the mouse c-fos gene.

1991 • 84 citations

Reversible and irreversible changes in nucleosome structure along the c-fos and c-myc oncogenes following inhibition of transcription

1990 • 74 citations

A study of mitochondrial and nuclear transcription with cloned cDNA probes

1985 • 73 citations

Differential regulation and expression of jun, c-fos and c-myc proto-oncogenes during mouse liver regeneration and after inhibition of protein synthesis.

1990 • 71 citations

Selective degradation of mRNA: the role of short-lived proteins in differential destabilization of insulin-induced creatine phosphokinase and myosin heavy chain mRNAs during rat skeletal muscle L6 cell differentiation.

1988 • 70 citations

Transcriptional Regulation of Two Serum-Induced RNAs in Mouse Fibroblasts: Equivalence of One Species to B2 Repetitive Elements

1985 • 46 citations

Overexpression of avian or mouse c-jun in primary chick embryo fibroblasts confers a partially transformed phenotype.

1990 • 45 citations

2-Aminopurine abolishes EGF- and TPA-stimulated pp33 phosphorylation and c-fos induction without affecting the activation of protein kinase C.

1990 • 44 citations

Ribosome changes during translation

1975 • 44 citations

Requirements for c-fos mRNA down regulation in growth stimulated murine cells.

1989 • 27 citations

Sequence Requirements for Premature Transcription Arrest within the First Intron of the Mouse c-fos Gene

1991 • 22 citations

c-fos Gene Transcription in Murine Macrophages Is Modulated by a Calcium-Dependent Block to Elongation in Intron 1

1991 • 14 citations

2-Aminopurine abolishes epidermal growth factor-stimulated phosphorylation of complexed and chromatin-associated forms of a 33 kDa phosphoprotein.

1989 • 14 citations

Rapid appearance of novel phosphoproteins in the nuclei of mitogen-stimulated fibroblasts.

1988 • 12 citations