Expression of Heme Oxygenase‐1 in Human Livers Before Transplantation Correlates with Graft Injury and Function After Transplantation

Real time quantitative PCR.

1996 • 6,155 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases

1997 • 2,481 citations

A novel method for real time quantitative RT-PCR.

1996 • 2,093 citations

PRESERVATION AND REPERFUSION INJURIES IN LIVER ALLOGRAFTS

1992 • 836 citations

Antioxidant activity of albumin-bound bilirubin.

1987 • 763 citations

Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP.

1995 • 709 citations

Pro-oxidant and cytotoxic effects of circulating heme

2002 • 596 citations

Selecting the donor liver: Risk factors for poor function after orthotopic liver transplantation

1994 • 542 citations

Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile.

1978 • 524 citations

Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

1999 • 493 citations

Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

1999 • 489 citations

THE PREDICTIVE VALUE OF DONOR LIVER BIOPSIES FOR THE DEVELOPMENT OF PRIMARY NONFUNCTION AFTER ORTHOTOPIC LIVER TRANSPLANTATION

1991 • 444 citations

Reversal of HO‐1 related cytoprotection with increased expression is due to reactive iron

1999 • 399 citations

Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

2001 • 396 citations

Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin

1993 • 394 citations

Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.

1995 • 388 citations

Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity.

1995 • 343 citations

Purification and characterization of biliverdin reductase from rat liver.

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Endothelial Heme Oxygenase-1 Induction by Hypoxia

2000 • 265 citations

Heme oxygenase: Protective gene or Trojan horse

1998 • 234 citations

Induction of Heme Oxygenase-1 Expression in Vascular Smooth Muscle Cells

1997 • 192 citations

Nitric oxide in liver injury

1999 • 191 citations

Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver

1998 • 176 citations

Heme Oxygenase-1 Gene Promoter Microsatellite Polymorphism is Associated with Restenosis after Percutaneous Transluminal Angioplasty

2001 • 163 citations

HEME OXYGENASE-1 OVEREXPRESSION PROTECTS RAT HEARTS FROM COLD ISCHEMIA/REPERFUSION INJURY VIA AN ANTIAPOPTOTIC PATHWAY1

2002 • 158 citations

Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning

2002 • 155 citations

Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury1

2002 • 153 citations

Carbon Monoxide as an Endogenous Modulator of Hepatic Vascular Perfusion

1994 • 151 citations

Heme Oxygenase-mediated Resistance to Oxygen Toxicity in Hamster Fibroblasts

1997 • 135 citations

Effect of Brain Death on Gene Expression and Tissue Activation in Human Donor Kidneys

2004 • 125 citations

Reduced plasma transforming growth factor-β1 levels in patients with chronic hepatitis C after interferon-α therapy: association with regression of hepatic fibrosis

1999 • 121 citations

Synergism between platelets and leukocytes in inducing endothelial cell apoptosis in the cold ischemic rat liver: a Kupffer cell mediated injury

2001 • 105 citations

Extended preservation of rat liver graft by induction of heme oxygenase-1

2002 • 104 citations

Altered expression of heme oxygenase-1 in the livers of patients with portal hypertensive diseases

2001 • 89 citations

Liver Transplantation, A 31 Year Perspective

1990 • 86 citations

Dopamine induces the expression of heme oxygenase-1 by human endothelial cells in vitro

2000 • 73 citations

Expression of a Constitutive Mutant of Iron Regulatory Protein 1 Abolishes Iron Homeostasis in Mammalian Cells

1995 • 64 citations

Spin trap (N-t-butyl-alpha-phenylnitrone)-mediated suprainduction of heme oxygenase-1 in kidney ischemia/reperfusion model: role of the oxygenase in protection against oxidative injury.

1999 • 58 citations

Differential activation pattern of redox-sensitive transcription factors and stress-inducible dilator systems heme oxygenase-1 and inducible nitric oxide synthase in hemorrhagic and endotoxic shock

2001 • 51 citations

Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals.

1999 • 51 citations

Induction ofHSP 32gene in hypoxic cardiomyocytes is attenuated by treatment withN-acetyl-<scp>l</scp>-cysteine

1998 • 48 citations

The HLA class III subregion is responsible for an increased breast cancer risk

2003 • 45 citations

The effect of a promoter polymorphism in the heme oxygenase-1 gene on the risk of ischaemic cerebrovascular events

2004 • 43 citations

Heme Oxygenase-1 Genotype is a Vascular Anti-inflammatory Factor following Balloon Angioplasty

2002 • 37 citations

The Role of Metals in Ischemia/Reperfusion Injury of the Liver

1996 • 36 citations

The structure, organization and differential expression of the rat gene encoding biliverdin reductase

1995 • 33 citations

Pretreatment of small bowel isograft donors with cobalt-protoporphyrin decreases preservation injury

1999 • 27 citations

Liver transplantation: A 31-year perspective part III

1990 • 25 citations

In liver transplantation, T tube bile represents total bile flow: Physiological and scintigraphic studies on biliary secretion of organic anions

1999 • 22 citations

Deregulation of iron homeostasis and cold-preservation injury to rat liver stored in University of Wisconsin solution

2003 • 18 citations