Tumoricidal Potential of Native Blood Dendritic Cells: Direct Tumor Cell Killing and Activation of NK Cell-Mediated Cytotoxicity

Dendritic cells and the control of immunity

1998 • 14,345 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Mouse and human dendritic cell subtypes

2002 • 2,311 citations

The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood

1999 • 2,255 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1999 • 1,754 citations

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

2001 • 1,728 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma

1999 • 1,260 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo

1999 • 1,066 citations

Reciprocal Activating Interaction between Natural Killer Cells and Dendritic Cells

2002 • 1,027 citations

Dendritic Cell Subsets and Lineages, and Their Functions in Innate and Adaptive Immunity

2001 • 1,010 citations

Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells

2002 • 986 citations

Characterization of human blood dendritic cell subsets

2002 • 739 citations

Contact-dependent Stimulation and Inhibition of Dendritic Cells by Natural Killer Cells

2002 • 704 citations

Dendritic Cells in Cancer Immunotherapy

2000 • 698 citations

Natural killer cells and dendritic cells: rendezvous in abused tissues

2002 • 674 citations

In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, Whereas Mature Dendritic Cells Are Located in Peritumoral Areas

1999 • 540 citations

Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect

2002 • 500 citations

Human Dendritic Cells Mediate Cellular Apoptosis via Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail)

1999 • 408 citations

Interplay of natural killer cells and their receptors with the adaptive immune response

2004 • 404 citations

The CD16+ (FcγRIII+) Subset of Human Monocytes Preferentially Becomes Migratory Dendritic Cells in a Model Tissue Setting

2002 • 360 citations

Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

2000 • 355 citations

NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs

2004 • 317 citations

Prognostic value of tumor‐infiltrating dendritic cells expressing CD83 in human breast carcinomas

2003 • 213 citations

6-Sulfo LacNAc, a Novel Carbohydrate Modification of PSGL-1, Defines an Inflammatory Type of Human Dendritic Cells

2002 • 211 citations

Tumor necrosis factor is an important mediator of tumor cell killing by human monocytes.

1987 • 192 citations

Different checkpoints in human NK-cell activation

2004 • 160 citations

S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival

1993 • 160 citations

Rat Spleen Dendritic Cells Express Natural Killer Cell Receptor Protein 1 (NKR-P1) and Have Cytotoxic Activity to Select Targets via a Ca2+-dependent Mechanism

1997 • 159 citations

Human renal-cell carcinoma tissue contains dendritic cells

1996 • 152 citations

A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) andin vitro priming of cytotoxic T lymphocytes

1998 • 151 citations

Enhancement of Human Cord Blood CD34+ Cell-Derived NK Cell Cytotoxicity by Dendritic Cells

2001 • 145 citations

Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. II. Role of TNF, Lymphotoxin-α1β2, Fas Ligand, and TNF-Related Apoptosis-Inducing Ligand

2002 • 131 citations

Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells

2004 • 117 citations

Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer

1990 • 108 citations

Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. I. Involvement of an Apoptosis-Inducing Pathway

2002 • 92 citations

In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells

2000 • 79 citations

Human monocyte-derived and CD83+ blood dendritic cells enhance NK cell-mediated cytotoxicity

2001 • 72 citations

Immunohistochemical evaluation of squamous cell carcinoma antigen and s-100 protein-positive cells in human malignant esophageal tissues

1990 • 69 citations

Prognostic Value of HLA-DR Expression and Dendritic Cell Infiltration in Gastric Cancer

1997 • 66 citations

Tumoricidal Activity of Monocyte-Derived Dendritic Cells: Evidence for a Caspase-8-Dependent, Fas-Associated Death Domain-Independent Mechanism

2001 • 64 citations

Mechanism of NK cell activation induced by coculture with dendritic cells derived from peripheral blood monocytes

2001 • 58 citations

Human dendritic cell mediated cytotoxicity against breast carcinoma cells in vitro

2002 • 55 citations

Native human blood dendritic cells as potent effectors in antibody-dependent cellular cytotoxicity

2002 • 49 citations

Interleukin‐12 secreted by mature dendritic cells mediates activation of NK cell function

2004 • 43 citations

Immature dendritic cells kill ovarian carcinoma cells by a FAS/FASL pathway, enabling them to sensitize tumor-specific CTLs

2001 • 42 citations

Peripheral Blood Dendritic Cells, but Not Monocyte-Derived Dendritic Cells, Can Augment Human NK Cell Function

2001 • 28 citations

Human dendritic cells induce tumor‐specific apoptosis by soluble factors

2002 • 24 citations

Interleukin 1 and tumour necrosis factor alpha may be responsible for the lytic mechanism during anti-tumour antibody-dependent cell-mediated cytotoxicity

1995 • 21 citations

In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells

2000 • 20 citations

Modulation of adenine nucleotide concentrations in human plasma by erythrocytes and endothelial cells

2003 • 6 citations