Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Structure and function of telomeres

1991 • 3,524 citations

A survey of telomerase activity in human cancer

1997 • 2,747 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

1997 • 1,786 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

TELOMERE LENGTH REGULATION

1996 • 1,010 citations

IMMUNODOMINANCE IN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I–RESTRICTED T LYMPHOCYTE RESPONSES

1999 • 923 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.

1995 • 871 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

1997 • 769 citations

Developmental and tissue-specific regulation of mouse telomerase and telomere length.

1995 • 686 citations

Isolation of a Candidate Human Telomerase Catalytic Subunit Gene, Which Reveals Complex Splicing Patterns in Different Cell Types

1997 • 586 citations

A New Era for Cancer Immunotherapy Based on the Genes that Encode Cancer Antigens

1999 • 578 citations

The Telomerase Catalytic Subunit Is a Widely Expressed Tumor-Associated Antigen Recognized by Cytotoxic T Lymphocytes

1999 • 574 citations

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors

1997 • 443 citations

Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA

1998 • 403 citations

Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)

1995 • 395 citations

The Makings of a Tumor Rejection Antigen

1999 • 389 citations

HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story

1999 • 366 citations

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

1998 • 332 citations

Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells.

2000 • 319 citations

Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines

1999 • 293 citations

Responsiveness to HY Antigen Ir Gene Complementation and Target Cell Specificity

1977 • 215 citations

Induction of carcinoembryonic antigen (cea)-specific cytotoxic t-lymphocyte responsesIn vitro using autologous dendritic cells loaded with cea peptide or cea rna in patients with metastatic malignancies expressing cea

1999 • 176 citations

Regulation of Telomere Length and Telomerase in T and B Cells

1998 • 154 citations

Expression profile of the putative catalytic subunit of the telomerase gene.

1998 • 152 citations

Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization

1997 • 132 citations

Telomere Length, Aging, and Somatic Cell Turnover

1999 • 108 citations

B7-CD28 costimulation unveils the hierarchy of tumor epitopes recognized by major histocompatibility complex class I-restricted CD8+ cytolytic T lymphocytes.

1996 • 100 citations

Hierarchy among multiple H-2b-restricted cytotoxic T-lymphocyte epitopes within simian virus 40 T antigen

1995 • 87 citations

Protection against lethal viral infection by vaccination with nonimmunodominant peptides.

1996 • 87 citations

H‐2K^b TRANSFECTION OF B16 MELANOMA CELLS RESULTS IN REDUCED TUMOURIGENICITY AND METASTATIC COMPETENCE

1989 • 63 citations

Do human cancers express sharedprotectiveantigens? or The necessity of remembrance of things past

1996 • 61 citations

Induction of CD8+ T Cell Responses to Dominant and Subdominant Epitopes and Protective Immunity to Sendai Virus Infection by DNA Vaccination

1998 • 60 citations

A fluorescence-based assay for quantitation of lymphokine-activated killer cell activity

1989 • 60 citations

Relationship Among Immunodominance of Single CD8+ T Cell Epitopes, Virus Load, and Kinetics of Primary Antiviral CTL Response

1998 • 55 citations

Immunodominant deters the response to other tumor antigens thereby favoring escape: prevention by vaccination with tumor variants selected with cloned cytolytic T cells in vitro

1996 • 34 citations

Chemotherapy of experimental transitional-cell carcinoma

1974 • 30 citations

Active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibits breast cancer metastases in tumor-bearing animals

1996 • 22 citations