In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

1998 • 1,226 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1998 • 1,218 citations

Pro‐inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum‐free conditions

1997 • 1,179 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

1996 • 959 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

1996 • 849 citations

Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice

1996 • 760 citations

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.

1994 • 607 citations

Dendritic cells in the T‐cell areas of lymphoid organs

1997 • 572 citations

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

1994 • 482 citations

Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway.

1997 • 443 citations

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors

1997 • 443 citations

Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors

1997 • 432 citations

Generation of Tumor Immunity by Bone Marrow-Derived Dendritic Cells Correlates with Dendritic Cell Maturation Stage

1999 • 430 citations

Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes.

1996 • 424 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity

1997 • 390 citations

Dendritic Cells Retrovirally Transduced with a Model Antigen Gene Are Therapeutically Effective against Established Pulmonary Metastases

1997 • 309 citations

Dendritic Cells Enhance Growth and Differentiation of CD40-activated B Lymphocytes

1997 • 301 citations

Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation.

1997 • 247 citations

Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10.

1993 • 241 citations

Induction of nitric oxide synthase in mouse dendritic cells by IFN-gamma, endotoxin, and interaction with allogeneic T cells: nitric oxide production is associated with dendritic cell apoptosis.

1996 • 210 citations

Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats

1997 • 186 citations

The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production

1982 • 179 citations

S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival

1993 • 160 citations

Rat Spleen Dendritic Cells Express Natural Killer Cell Receptor Protein 1 (NKR-P1) and Have Cytotoxic Activity to Select Targets via a Ca2+-dependent Mechanism

1997 • 159 citations

Human renal-cell carcinoma tissue contains dendritic cells

1996 • 152 citations

Follow-up evaluation of prostate cancer patients infused with autologous dendritic cells pulsed with PSMA peptides

1997 • 126 citations

Inactivation of macrophage nitric oxide synthase activity by NG-Methyl-L-arginine

1991 • 111 citations

Generation of dendritic cells from bone marrow progenitors using GM‐CSF, TNF‐&alpha;, and additional cytokines: antagonistic effects of IL‐4 and IFN‐&gamma; and selective involvement of TNF‐&alpha; receptor‐1

1997 • 96 citations

Retrovirally Transduced Bone Marrow-Derived Dendritic Cells Require CD4+ T Cell Help to Elicit Protective and Therapeutic Antitumor Immunity

1999 • 87 citations

Differential Expression of Viral and Human Interleukin-10 (IL-10) by Primary B Cell Tumors and B Cell Lines

1994 • 66 citations

Human follicular dendritic cells enhance cytokine-dependent growth and differentiation of CD40-activated B cells.

1995 • 58 citations

Differential Effects of LPS and CD40 Ligand Stimulations on the Induction of IL-12 Production by Dendritic Cells and Macrophages

1997 • 56 citations

NITRIC OXIDE PRODUCTION BY MOUSE BONE MARROW-DERIVED DENDRITIC CELLS

1996 • 55 citations

Immunotherapeutic Potential of Tumor Antigen-Pulsed and Unpulsed Dendritic Cells Generated from Murine Bone Marrow

1997 • 46 citations

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