Mice lacking the transcription factor subunit Rel can clear an influenza infection and have functional anti-viral cytotoxic T cells but do not develop an optimal antibody response

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1983 • 561 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

Effector CD4⁺ and CD8⁺ T‐cell mechanisms in the control of respiratory virus infections

1997 • 430 citations

Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis

1995 • 392 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes.

1993 • 304 citations

A procedure for removing red cells and dead cells from lymphoid cell suspensions

1975 • 303 citations

NF-κB RelA-deficient Lymphocytes: Normal Development of T Cells and B Cells, Impaired Production of IgA and IgG1 and Reduced Proliferative Responses

1997 • 296 citations

Role of the B‐cell response in recovery of mice from primary influenza virus infection

1997 • 240 citations

Failure of Lymphopoiesis after Adoptive Transfer of NF-κB–Deficient Fetal Liver Cells

1997 • 193 citations

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor.

1996 • 147 citations

Recovery from a viral respiratory infection. I. Influenza pneumonia in normal and T-deficient mice.

1981 • 138 citations

Multifocal defects in immune responses in RelB-deficient mice.

1997 • 131 citations

The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations.

1996 • 120 citations

Characteristics of the influenza virus-specific CD8+ T cell response in mice homozygous for disruption of the H-2lAb gene.

1995 • 118 citations

Influenza virus RNA in the lung and lymphoid tissue of immunologically intact and CD4-depleted mice

1991 • 115 citations

Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: association with nuclear factor kappa B activation.

1994 • 107 citations

Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens

1984 • 107 citations

The subunit composition of NF-kappa B complexes changes during B-cell development.

1994 • 93 citations

Priming of influenza virus-specific cytotoxic T lymphocytes vivo by short synthetic peptides.

1991 • 88 citations

CD4+T Cells Are Ineffective in Clearing a Pulmonary Infection with Influenza Type A Virus in the Absence of B Cells

1997 • 87 citations

The Rel family: models for transcriptional regulation and oncogenic transformation

1992 • 80 citations

Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs

1994 • 63 citations

Antigenic Determinants of Influenza Virus Hemagglutinin

1979 • 49 citations

Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.

1987 • 46 citations

Antigenic determinants of influenza virus hemagglutinin XII. The epitopes of a synthetic peptide representing the C-terminus of HA1

1986 • 37 citations

The murine c-rel proto-oncogene encodes two mRNAs the expression of which is modulated by lymphoid stimuli.

1990 • 36 citations

Immunopotentiation of humoral and cellular responses to inactivated influenza vaccines by two different adjuvants with potential for human use

1998 • 28 citations

Expression of the c-rel and c-myc proto-oncogenes in avian tissues.

1989 • 23 citations

Class II-restricted T-cell clones to a synthetic peptide of influenza virus hemagglutinin differ in their fine specificities and in the ability to respond to virus

1989 • 21 citations

A study of the advantages and limitations of immunoblotting procedures for the detection of antibodies against influenza virus

1993 • 6 citations