Interleukin-8 Controls Bacterial Transepithelial Translocation at the Cost of Epithelial Destruction in Experimental Shigellosis

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

Interleukin-10

1993 • 1,820 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

Shigella flexneri induces apoptosis in infected macrophages

1992 • 1,130 citations

Essential involvement of interleukin-8 (IL-8) in acute inflammation

1994 • 982 citations

Topley and Wilson's Microbiology and Microbial infections

1998 • 812 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Involvement of a plasmid in the invasive ability of Shigella flexneri

1982 • 733 citations

Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry

1993 • 663 citations

Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8

1993 • 529 citations

Host-Pathogen Interactions

1983 • 474 citations

A bacterial invasin induces macrophage apoptosis by binding directly to ICE.

1996 • 405 citations

Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole

1992 • 315 citations

Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis.

1994 • 289 citations

A primer on cytokines: sources, receptors, effects, and inducers

1997 • 286 citations

Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation.

1994 • 282 citations

Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease.

1996 • 280 citations

Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis

1989 • 272 citations

Bacterial Perturbation of Cytokine Networks

1998 • 249 citations

IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding.

1993 • 246 citations

Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils.

1995 • 237 citations

Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri.

1994 • 209 citations

Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri.

1994 • 207 citations

Perspectives series: host/pathogen interactions. Apoptosis in bacterial pathogenesis.

1997 • 206 citations

Apoptosis as a proinflammatory event: What can we learn from bacteria-induced cell death?

1997 • 187 citations

Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium

1996 • 179 citations

Interleukin 8: cells of origin in inflammatory bowel disease.

1996 • 177 citations

Persistence of local cytokine production in shigellosis in acute and convalescent stages

1995 • 174 citations

In vivo apoptosis in Shigella flexneri infections

1996 • 173 citations

OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis

1991 • 172 citations

Human intestinal epithelial cells produce proinflammatory cytokines in response to infection in a SCID mouse-human intestinal xenograft model of amebiasis

1997 • 165 citations

Microbiology and Microbial Infections

1998 • 145 citations

Neutralization of IL-8 inhibits neutrophil influx in a rabbit model of endotoxin-induced pleurisy.

1994 • 142 citations

Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells

1994 • 138 citations

Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha.

1995 • 137 citations

Role of interleukin-1 in the pathogenesis of experimental shigellosis.

1995 • 136 citations

Morphology of Rectal Mucosa of Patients with Shigellosis

1991 • 129 citations

Cytokine Secretion in Acute Shigellosis Is Correlated to Disease Activity and Directed More to Stool than to Plasma

1995 • 124 citations

Interleukin 8 as a novel target for intervention therapy in acute inflammatory diseases

1996 • 116 citations

A sensitive enzyme-linked immunosorbent assay for human interleukin-8

1992 • 110 citations

Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis.

1993 • 110 citations

Interleukin 8 secretion by colonic crypt cells in vitro: response to injury suppressed by butyrate and enhanced in inflammatory bowel disease.

1995 • 108 citations

An Essential Role for Gamma Interferon in Innate Resistance toShigella flexneriInfection

1998 • 96 citations

Prevention of endotoxemia-induced acute respiratory distress syndrome-like lung injury in rabbits by a monoclonal antibody to IL-8.

1997 • 90 citations

Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate.

1995 • 82 citations

Pathogenetic and clinical relevance of cytokines in inflammatory bowel disease

1991 • 73 citations

Trafficking of Shigella Lipopolysaccharide in Polarized Intestinal Epithelial Cells

1999 • 55 citations

Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes

1997 • 54 citations

Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation.

1994 • 32 citations

Effects of interleukin-8 on nonspecific resistance to infection in neutropenic and normal mice

1993 • 28 citations

Epithelial cytokines in intestinal inflammation and mucosal immunity

1997 • 21 citations

[Clinical implication of IL-10 in patients with immune and inflammatory diseases].

1994 • 12 citations

Cytokines and chemokines in inflammatory bowel disease

1995 • 7 citations

Inflammatory mediators in inflammatory bowel disease

1996 • 4 citations

Deleted Work

1955 • 0 citations