Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes

Shigella flexneri induces apoptosis in infected macrophages

1992 • 1,130 citations

Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

1993 • 845 citations

Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides

1976 • 818 citations

Involvement of a plasmid in the invasive ability of Shigella flexneri

1982 • 733 citations

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

1989 • 724 citations

EPITHELIAL CELL PENETRATION AS AN ESSENTIAL STEP IN THE PATHOGENESIS OF BACILLARY DYSENTERY

1964 • 628 citations

Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis

1986 • 509 citations

Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils.

1990 • 478 citations

Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.

1993 • 460 citations

Occluding junction structure-function relationships in a cultured epithelial monolayer.

1985 • 412 citations

Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction.

1991 • 352 citations

Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein

1989 • 351 citations

Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation

1987 • 327 citations

Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole

1992 • 315 citations

A genetic determinant required for continuous reinfection of adjacent cells on large plasmid in S. flexneri 2a

1986 • 312 citations

Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on lipopolysaccharide binding protein and CD14.

1991 • 300 citations

Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis.

1994 • 289 citations

Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis

1989 • 272 citations

Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils.

1995 • 237 citations

Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide.

1994 • 236 citations

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms

1994 • 213 citations

Neutrophil CD14: biochemical properties and role in the secretion of tumor necrosis factor-alpha in response to lipopolysaccharide.

1993 • 211 citations

Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri.

1994 • 209 citations

Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri.

1994 • 207 citations

Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14.

1996 • 207 citations

Potentially Lethal Complications of Shigellosis

1991 • 180 citations

Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium

1996 • 179 citations

OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis

1991 • 172 citations

Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis.

1995 • 168 citations

Morphology of Rectal Mucosa of Patients with Shigellosis

1991 • 129 citations

Binding, internalization, and deacylation of bacterial lipopolysaccharide by human neutrophils.

1993 • 96 citations

Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanism

1995 • 91 citations

Enzymatic deacylation of the lipid A moiety of Salmonella typhimurium lipopolysaccharides by human neutrophils.

1983 • 89 citations

Shigella subversion of the cellular cytoskeleton: a strategy for epithelial colonization

1993 • 84 citations

Inflammatory bowel disease is associated with increased mucosal levels of bactericidal/permeability-increasing protein

1996 • 75 citations

Stress fiber-based movement of Shigella flexneri within cells

1991 • 68 citations

A structure-activity relationship for induction of meningeal inflammation by muramyl peptides.

1993 • 64 citations

Different signaling pathways for CD18-mediated adhesion and Fc-mediated phagocytosis. Response of neutrophils to LPS.

1994 • 44 citations

A comparison of the effects of intact and deacylated lipopolysaccharide on human polymorphonuclear leukocytes.

1990 • 34 citations

Induction of adherence and degranulation of polymorphonuclear leukocytes: a new expression of the invasive phenotype of Shigella flexneri

1996 • 19 citations

Effect of 24 Antimicrobial Drugs on Polymorphonuclear Leukocyte Adherence

1985 • 10 citations