Mutational mapping of RAS-responsive domains of the Saccharomyces cerevisiae adenylyl cyclase.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure

1989 • 745 citations

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1987 • 703 citations

Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.

1987 • 504 citations

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

1984 • 471 citations

DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase

1985 • 429 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae.

1987 • 230 citations

Mammalian and Yeast ras Gene Products: Biological Function in Their Heterologous Systems

1985 • 209 citations

SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits.

1988 • 198 citations

Adenylate cyclases in yeast: a comparison of the genes from Schizosaccharomyces pombe and Saccharomyces cerevisiae.

1989 • 118 citations

Mutations of the Adenylyl Cyclase Gene that Block RAS Function in Saccharomyces cerevisiae

1990 • 109 citations

Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae.

1987 • 101 citations

The adenylyl cyclase gene from Schizosaccharomyces pombe.

1989 • 96 citations

Suppression of defective RAS1 and RAS2 functions in yeast by an adenylate cyclase activated by a single amino acid change.

1986 • 93 citations

An Adenylate Cyclase from Saccharomyces cerevisiae That Is Stimulated by RAS Proteins with Effector Mutations

1988 • 50 citations

Identification of the domain of Saccharomyces cerevisiae adenylate cyclase associated with the regulatory function of RAS products

1987 • 35 citations

An adenylate cyclase from Saccharomyces cerevisiae that is stimulated by RAS proteins with effector mutations.

1988 • 27 citations