Mutations of the Adenylyl Cyclase Gene that Block RAS Function in Saccharomyces cerevisiae

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Experiments With Gene Fusions

1984 • 2,487 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

1988 • 1,077 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Lutropin-Choriogonadotropin Receptor: An Unusual Member of the G Protein-Coupled Receptor Family

1989 • 955 citations

Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP

1988 • 757 citations

Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers

1989 • 676 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.

1982 • 558 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase

1985 • 429 citations

Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein.

1987 • 376 citations

Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum.

1985 • 313 citations

Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.

1986 • 295 citations

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects.

1986 • 285 citations

The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.

1988 • 254 citations

Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae.

1987 • 221 citations

Chaoptin, a cell surface glycoprotein required for Drosophila photoreceptor cell morphogenesis, contains a repeat motif found in yeast and human

1988 • 218 citations

Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase.

1989 • 192 citations

The ras oncogene--an important regulatory element in lower eucaryotic organisms

1989 • 189 citations

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae.

1989 • 162 citations

Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib.

1987 • 143 citations

Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats

1988 • 98 citations

Mutants of H-ras that interfere with RAS effector function in Saccharomyces cerevisiae.

1989 • 51 citations