T-Cell Responses Directed against Multiple HLA-A*0201-Restricted Epitopes Derived from Wilms' Tumor 1 Protein in Patients with Leukemia and Healthy Donors: Identification, Quantification, and Characterization

Real time quantitative PCR.

1996 • 6,155 citations

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

1993 • 962 citations

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

2000 • 679 citations

WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia

1994 • 575 citations

Tumor antigens recognized by T cells

1997 • 552 citations

Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

2004 • 528 citations

Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis.

1995 • 522 citations

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

1996 • 520 citations

NK susceptibility varies inversely with target cell class I HLA antigen expression.

1987 • 433 citations

Selective elimination of leukemic CD34+ progenitor cells by cytotoxic T lymphocytes specific for WT1

2000 • 420 citations

Graft-versus-Host Disease as Adoptive Immunotherapy in Patients with Advanced Hematologic Neoplasms

1989 • 361 citations

HLA class I-restricted lysis of leukemia cells by a CD8+ cytotoxic T-lymphocyte clone specific for WT1 peptide

2000 • 351 citations

ASSOCIATION OF CYTOKINE POLYMORPHIC INHERITANCE AND IN VITRO CYTOKINE PRODUCTION IN ANTI-CD3/CD28-STIMULATED PERIPHERAL BLOOD LYMPHOCYTES1

2001 • 345 citations

Tetrameric HLA class I–minor histocompatibility antigen peptide complexes demonstrate minor histocompatibility antigen-specific cytotoxic T lymphocytes in patients with graft-versus-host disease

1999 • 277 citations

Development of a Candidate HLA A*0201 Restricted Peptide-Based Vaccine Against Human Cytomegalovirus Infection

1997 • 268 citations

Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias.

1995 • 263 citations

CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

2002 • 259 citations

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene ( WT1 ) product

2000 • 250 citations

Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation

2003 • 219 citations

Cancer Immunotherapy Targeting Wilms’ Tumor Gene WT1 Product

2000 • 211 citations

Induction of anti-self-immunity to cure cancer

1995 • 207 citations

Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

1999 • 206 citations

A Novel Approach to the Analysis of Specificity, Clonality, and Frequency of HIV-Specific T Cell Responses Reveals a Potential Mechanism for Control of Viral Escape

2002 • 203 citations

Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host disease

2001 • 179 citations

Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen

1996 • 173 citations

Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood

1997 • 169 citations

The Human CD8 Coreceptor Effects Cytotoxic T Cell Activation and Antigen Sensitivity Primarily by Mediating Complete Phosphorylation of the T Cell Receptor ζ Chain

2001 • 155 citations

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

2000 • 144 citations

Wilms tumor gene peptide-based immunotherapy for patients with overt Leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis

2003 • 124 citations

Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.

1991 • 117 citations

The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells.

1994 • 115 citations

Two distinct HLA-A0201–presented epitopes of the Wilms tumor antigen 1 can function as targets for leukemia-reactive CTL

2002 • 110 citations

The CD8 T Cell Coreceptor Exhibits Disproportionate Biological Activity at Extremely Low Binding Affinities

2003 • 101 citations

High Avidity Antigen-Specific CTL Identified by CD8-Independent Tetramer Staining

2003 • 86 citations

Cytotoxic T-lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination.

2000 • 75 citations

α3 Domain Mutants of Peptide/MHC Class I Multimers Allow the Selective Isolation of High Avidity Tumor-Reactive CD8 T Cells

2003 • 58 citations

Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies

2004 • 53 citations

Immunodominant minor histocompatibility antigens expressed by mouse leukemic cells can serve as effective targets for T cell immunotherapy.

1995 • 39 citations

Selective elimination of leukemic CD34+ progenitor cells by cytotoxic T lymphocytes specific for WT1

2000 • 28 citations

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

2000 • 27 citations

Flow cytometric quantitation and characterization of the T-lymphocyte memory response to CMV in healthy donors

2002 • 23 citations

HLA class I-restricted lysis of leukemia cells by a CD8+ cytotoxic T-lymphocyte clone specific for WT1 peptide

2000 • 22 citations

Immune escape mechanisms of childhood ALL and a potential countering role for DC-like leukemia cells

2002 • 12 citations

Human Immune Interferon (IFN-γ) Gene Sequence and Structure

1983 • 11 citations