HLA class I-restricted lysis of leukemia cells by a CD8+ cytotoxic T-lymphocyte clone specific for WT1 peptide

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

The candidate Wilms' tumour gene is involved in genitourinary development

1990 • 884 citations

WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia

1994 • 575 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

Expression of the Wilms' tumor gene WT1 in the murine urogenital system.

1991 • 447 citations

Aberrant Overexpression of the Wilms Tumor Gene (WT1) in Human Leukemia

1997 • 375 citations

Expression of the Wilms' tumor gene (WT1) in human leukemias.

1992 • 354 citations

High Levels of Wilms' Tumor Gene (wt1) mRNA in Acute Myeloid Leukemias Are Associated With a Worse Long-Term Outcome

1997 • 348 citations

Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells

1996 • 341 citations

Use of Leukemic Dendritic Cells for the Generation of Antileukemic Cellular Cytotoxicity Against Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia

1997 • 309 citations

Specific human cellular immunity to bcr-abl oncogene-derived peptides

1996 • 300 citations

Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

1996 • 268 citations

Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias.

1995 • 263 citations

A new leukemia cell line with philadelphia chromosome characterized as basophil precursors

1985 • 261 citations

The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor

1993 • 254 citations

Cytotoxic T Lymphocytes Specific for a Nonpolymorphic Proteinase 3 Peptide Preferentially Inhibit Chronic Myeloid Leukemia Colony-Forming Units

1997 • 245 citations

Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia.

1998 • 244 citations

Dendritic Cells Derived In Vitro From Acute Myelogenous Leukemia Cells Stimulate Autologous, Antileukemic T-Cell Responses

1999 • 241 citations

The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesothelioma

1993 • 211 citations

Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide

1996 • 200 citations

Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma.

1995 • 197 citations

Long-term follow-up of minimal residual disease in leukemia patients by monitoring WT1 (Wilms tumor gene) expression levels

1996 • 187 citations

Sequence-based association analysis of HLA class I and II alleles in Japanese supports conservation of common haplotypes

1997 • 185 citations

Tissue, Developmental, and Tumor-Specific Expression of Divergent Transcripts in Wilms Tumor

1990 • 166 citations

Human CD4 lymphocytes specifically recognize a peptide representing the fusion region of the hybrid protein pml/RAR alpha present in acute promyelocytic leukemia cells

1993 • 141 citations

Dendritic Cells Stimulate the Expansion of bcr-abl Specific CD8+ T Cells With Cytotoxic Activity Against Leukemic Cells From Patients With Chronic Myeloid Leukemia

1998 • 133 citations

DNA typing of the HLA‐A gene: population study and identification of four new alleles in Japanese

1996 • 126 citations

Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia.

1998 • 115 citations

The Wilms' tumor gene is expressed in a subset of CD34+ progenitors and downregulated early in the course of differentiation in vitro.

1997 • 115 citations

Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia

1997 • 114 citations

Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24.

1997 • 107 citations

HLA-DR1–Restricted bcr-abl (b3a2)-Specific CD4+ T Lymphocytes Respond to Dendritic Cells Pulsed With b3a2 Peptide and Antigen-Presenting Cells Exposed to b3a2 Containing Cell Lysates

1997 • 105 citations

Dendritic cells generated from blood precursors of chronic myelogenous leukemia patients carry the philadelphia translocation and can induce a CML-specific primary cytotoxic T-cell response

1997 • 104 citations

Generation of bcr-abl specific cytotoxic T-lymphocytes by using dendritic cells pulsed with bcr-abl (b3a2) peptide: its applicability for donor leukocyte transfusions in marrow grafted CML patients

1999 • 95 citations

Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules.

1995 • 90 citations

Two brc-abl junction peptides bind HLA-A3 molecules and allow specific induction of human cytotoxic T lymphocytes.

1996 • 87 citations

CD4(+) cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner

1998 • 72 citations

Functional heterogeneity among herpes simplex virus-specific human CD4+ T cells.

1991 • 71 citations

Cytotoxic T‐lymphocyte (CTL) responses against acute or chronic myeloid leukemia

1997 • 71 citations

Constitutive expression of the Wilms tumor suppressor gene (WT1) in renal cell carcinoma

1998 • 71 citations

Wilms Tumor Gene (wt1) mRNA Is Equally Expressed in Blast Cells From Acute Myeloid Leukemia and Normal CD34+ Progenitors

1997 • 70 citations

Peptides derived from the whole sequence of BCR‐ABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes

1997 • 64 citations

HLA-B51 transgenic mice as recipients for production of polymorphic HLA-A, B-specific antibodies

1993 • 47 citations

Fas-Independent and Nonapoptotic Cytotoxicity Mediated by a Human CD4+ T-Cell Clone Directed Against an Acute Myelogenous Leukemia–Associated DEK-CAN Fusion Peptide

1999 • 44 citations

Molecular mechanisms possibly affecting WT1 function in human ovarian tumors

1994 • 43 citations

Role of strong anchor residues in the effective binding of 10-mer and 11-mer peptides to HLA-A*2402 molecules

1996 • 39 citations

Expression of perforin and membrane-bound lymphotoxin (tumor necrosis factor-beta) in virus-specific CD4+ human cytotoxic T-cell clones

1993 • 39 citations

Serologic and nucleotide sequencing analyses of a novel DR52-associated DRB1 allele with the DR ‘NJ25’ specificity, designated DRB1∗1307

1994 • 34 citations