Wilms tumor gene peptide-based immunotherapy for patients with overt Leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia

1994 • 575 citations

Selective elimination of leukemic CD34+ progenitor cells by cytotoxic T lymphocytes specific for WT1

2000 • 420 citations

Aberrant Overexpression of the Wilms Tumor Gene (WT1) in Human Leukemia

1997 • 375 citations

Expression of the Wilms' tumor gene (WT1) in human leukemias.

1992 • 354 citations

HLA class I-restricted lysis of leukemia cells by a CD8+ cytotoxic T-lymphocyte clone specific for WT1 peptide

2000 • 351 citations

Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

1996 • 268 citations

Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias.

1995 • 263 citations

CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

2002 • 259 citations

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene ( WT1 ) product

2000 • 250 citations

Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level

2000 • 242 citations

Phase I trial of a MART-1 peptide vaccine with incomplete Freund's adjuvant for resected high-risk melanoma.

1999 • 223 citations

Expression of the Wilms' Tumor Gene WT1 in Solid Tumors and Its Involvement in Tumor Cell Growth

1999 • 216 citations

Cancer Immunotherapy Targeting Wilms’ Tumor Gene WT1 Product

2000 • 211 citations

Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers

2002 • 205 citations

High expression of Wilms' tumor suppressor gene predicts poor prognosis in breast cancer patients.

2002 • 202 citations

The Wilms’ tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes

1999 • 188 citations

Wilms' Tumor Gene (WT1) Competes With Differentiation-Inducing Signal in Hematopoietic Progenitor Cells

1998 • 178 citations

Expression of the candidate Wilm's tumor gene, WT1, in human leukemia cells.

1993 • 152 citations

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

2000 • 144 citations

Wilms’ Tumor GeneWT1: Its Oncogenic Function and Clinical Application

2001 • 130 citations

Humoral immune responses against Wilms tumor gene WT1product in patients with hematopoietic malignancies

2002 • 124 citations

The Wilms' Tumor 1 Gene: Oncogene or Tumor Suppressor Gene?

1998 • 121 citations

The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells.

1994 • 115 citations

Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues

2002 • 115 citations

Constitutive expression of the Wilms’ tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF)

1999 • 99 citations

WT1 as a Novel Target Antigen for Cancer Immunotherapy

2002 • 75 citations

Cytotoxic T-lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination.

2000 • 75 citations

Antilung cancer effect of WT1-specific cytotoxic T lymphocytes.

2002 • 57 citations

HLA class II haplotype and quantitation of WT1 RNA in Japanese patients with paroxysmal nocturnal hemoglobinuria

2002 • 53 citations

Myelodysplastic syndrome: review of the cytogenetic and molecular data

2001 • 51 citations

Cytogenetic clonality analysis in myelodysplastic syndrome: monosomy 7 can be demonstrated in the myeloid and in the lymphoid lineage.

1995 • 49 citations

Combined immunophenotyping and FISH identifies the involvement of B-cells in 5q- syndrome

2000 • 46 citations

Cancer Immunotherapy Targeting WT1 Protein

2002 • 40 citations

Involvement of natural killer cells in patients with myelodysplastic syndrome carrying monosomy 7 revealed by the application of fluorescence in situ hybridization to cells collected by means of fluorescence‐activated cell sorting

2000 • 38 citations

Development of HLA‐A2402/K^b transgenic mice

2002 • 28 citations